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{ "products": [ { "_id": "6a6def248b0777b5cb29791c", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Propranolol Hydrochloride Sustained Release Capsules IP", "description": "PROPASULES LA 40 is a premium pharmaceutical formulation containing Propranolol Hydrochloride Sustained Release Capsules IP 40 mg. Developed with advanced sustained-release technology, this formulation delivers the active ingredient gradually over an extended period, helping maintain consistent therapeutic levels while supporting the convenience of once-daily administration when prescribed by a healthcare professional.\n\nManufactured in GMP-certified facilities using pharmaceutical-grade raw materials, PROPASULES LA 40 is produced under strict quality control measures to ensure purity, safety, and batch-to-batch consistency. It is intended for the treatment of medical conditions in which propranolol therapy is considered appropriate by a qualified physician.\n\nComposition\n\nEach Sustained Release Capsule Contains:\n\nPropranolol Hydrochloride IP – 40 mg\nSustained Release Pellets\nPharmaceutical Excipients – q.s.\nCapsule Shell – Approved pharmaceutical-grade ingredients\n\nDosage Form: Sustained Release Capsules\n\nWhat is PROPASULES LA 40?\n\nPROPASULES LA 40 contains Propranolol Hydrochloride, a non-selective beta-adrenergic receptor blocker (beta-blocker) that helps manage a variety of cardiovascular and neurological conditions. The sustained-release formulation is specifically designed to release the medicine gradually throughout the day, providing prolonged therapeutic action and helping maintain stable plasma drug concentrations compared with conventional immediate-release formulations.\n\nIts controlled-release technology enhances dosing convenience and supports consistent treatment outcomes when used according to medical advice.\n\nKey Features\nContains Propranolol Hydrochloride Sustained Release IP 40 mg\nAdvanced sustained-release technology for prolonged drug delivery\nSupports once-daily dosing as prescribed\nManufactured using premium pharmaceutical-grade ingredients\nProduced in GMP-compliant manufacturing facilities\nStringent quality assurance for consistent product performance\nReliable formulation for long-term therapeutic use under medical supervision\nTherapeutic Uses\n\nHealthcare professionals may prescribe PROPASULES LA 40 for the management of several cardiovascular and neurological disorders, including:\n\nHypertension (high blood pressure)\nChronic stable angina\nCardiac arrhythmias\nPrevention of migraine attacks\nEssential tremor\nPhysical symptoms associated with anxiety\nCardiovascular manifestations of hyperthyroidism\nSecondary prevention following myocardial infarction, when clinically indicated\n\nThe choice of treatment, dosage, and duration should always be individualized based on the patient's medical condition and physician's assessment.\n\nHow PROPASULES LA 40 Works\n\nPropranolol Hydrochloride works by blocking beta-adrenergic receptors located in the heart and other tissues. This action reduces the effects of adrenaline and other stress hormones on the cardiovascular system.\n\nAs a result, the medicine may help:\n\nSlow the heart rate\nReduce the workload on the heart\nLower elevated blood pressure\nImprove control of certain abnormal heart rhythms\nReduce the frequency of migraine episodes\nMinimize symptoms associated with essential tremor\nRelieve physical manifestations of anxiety, such as rapid heartbeat and trembling\n\nThe sustained-release pellets gradually release the medication throughout the day, providing prolonged therapeutic coverage and reducing fluctuations in drug levels.\n\nBenefits of the Sustained Release Formulation\n\nThe advanced sustained-release technology offers several advantages:\n\nControlled and gradual release of the active ingredient\nExtended therapeutic effect throughout the dosing interval\nMore consistent blood concentrations of the medication\nReduced peak-to-trough fluctuations compared with immediate-release formulations\nConvenient dosing schedule that may improve treatment adherence\nSuitable for long-term therapy under medical supervision\n\nTreatment outcomes depend on individual patient response and adherence to the prescribed regimen.\n\nDosage and Administration\n\nTake PROPASULES LA 40 exactly as instructed by your healthcare provider.\n\nGeneral recommendations include:\n\nSwallow the capsule whole with sufficient water.\nDo not crush, chew, or open the capsule unless specifically advised.\nTake the medicine at the same time every day.\nFollow the prescribed dosage schedule carefully.\nDo not discontinue treatment abruptly without consulting your physician, as sudden withdrawal may increase the risk of cardiovascular complications.\nPossible Side Effects\n\nLike all medications, PROPASULES LA 40 may cause side effects in some individuals, although many patients tolerate it well.\n\nCommon side effects may include:\n\nFatigue\nDizziness\nSlow heartbeat\nCold hands and feet\nNausea\nSleep disturbances\nMild stomach discomfort\n\nSeek immediate medical attention if you experience breathing difficulty, severe dizziness, fainting, swelling of the face or throat, or signs of a serious allergic reaction.\n\nConsult your healthcare provider if any side effects persist or become troublesome.\n\nPrecautions and Warnings\n\nBefore starting PROPASULES LA 40, inform your doctor if you have:\n\nAsthma or chronic obstructive pulmonary disease (COPD)\nDiabetes mellitus\nLiver impairment\nKidney disease\nHeart failure\nLow blood pressure\nBradycardia (slow heart rate)\nPeripheral vascular disease\nThyroid disorders\nHistory of hypersensitivity reactions\n\nYour physician should also be informed about all prescription medicines, over-the-counter drugs, herbal supplements, and dietary products you are taking to minimize the risk of drug interactions.\n\nPregnancy and Breastfeeding\n\nThe use of PROPASULES LA 40 during pregnancy or breastfeeding should only be considered when recommended by a qualified healthcare professional after carefully evaluating the potential benefits and possible risks.\n\nAlways consult your physician before taking this medicine during pregnancy or while nursing.\n\nStorage Instructions\n\nTo maintain product quality:\n\nStore in a cool and dry place.\nProtect from moisture and direct sunlight.\nKeep below the storage temperature specified on the product label.\nStore in the original packaging until use.\nKeep out of the reach of children.\nDo not use the medicine after the expiry date printed on the pack.\nWhy Choose PROPASULES LA 40?\n\nPROPASULES LA 40 is formulated to deliver dependable therapeutic performance through advanced sustained-release technology. Manufactured under stringent pharmaceutical quality standards, it combines consistent drug delivery, convenient dosing, and reliable product quality to support long-term cardiovascular and neurological care.\n\nKey Advantages\n\nPremium sustained-release Propranolol formulation\nControlled drug release for prolonged therapeutic action\nConvenient once-daily administration as prescribed\nManufactured in GMP-certified facilities\nHigh standards of quality, purity, and consistency\nReliable formulation for chronic disease management\nFrequently Asked Questions (FAQs)\nWhat is PROPASULES LA 40 prescribed for?\n\nPROPASULES LA 40 may be prescribed for conditions such as hypertension, chronic angina, cardiac arrhythmias, migraine prevention, essential tremor, anxiety-related physical symptoms, and certain cardiovascular conditions, depending on the physician's evaluation.\n\nCan PROPASULES LA 40 be taken once a day?\n\nYes. The sustained-release formulation is designed to support convenient once-daily dosing when prescribed by a healthcare professional.\n\nCan I stop taking PROPASULES LA 40 suddenly?\n\nNo. Abrupt discontinuation of propranolol may increase the risk of serious cardiovascular events. Always consult your doctor before stopping treatment.\n\nCan people with diabetes take PROPASULES LA 40?\n\nPatients with diabetes should use this medicine only under medical supervision, as beta-blockers may mask some warning signs of low blood sugar.\n\nIs PROPASULES LA 40 suitable for every patient?\n\nNo. This medicine may not be appropriate for individuals with certain conditions such as severe asthma, significant bradycardia, or specific cardiac disorders. Your healthcare provider will determine whether it is suitable for your individual medical needs.", "price": 45.0, "discountamount": 14.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2490, "imageuri": "https://productimages.withfloats.com/actual/6a6def271f223d84dee2d962.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a6def271f223d84dee2d962.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-08-01T13:05:40.676Z", "updatedon": "2026-08-01T13:05:40.676Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/propranolol-hydrochloride-sustained-release-capsules-ip/2490", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "PROPASULES LA 40", "category": "CARDIOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69e9ed91fa23eada60366b93", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "nebivolol 2.5mg and cilnidipine 10 mg", "description": "If you are searching for an effective and well-balanced treatment for high blood pressure (hypertension), the combination of nebivolol 2.5mg and cilnidipine 10 mg is a modern and highly recommended therapy. This dual-action medication is designed to not only control blood pressure but also protect your heart and blood vessels over the long term.\n\nIn this buyer-focused guide, you will learn everything about nebivolol 2.5 mg and cilnidipine 10 mg, including how it works, benefits, dosage, safety, side effects, and what to consider before purchasing.\n\nWhat is Nebivolol 2.5mg and Cilnidipine 10 mg?\n\nNebivolol 2.5mg and cilnidipine 10 mg is a combination medicine used to treat hypertension. It combines two powerful agents:\n\nNebivolol (2.5mg): A beta-blocker that reduces heart rate and relaxes blood vessels\nCilnidipine (10mg): A calcium channel blocker that widens blood vessels and improves circulation\n\nTogether, these components work synergistically to provide effective and sustained blood pressure control.\n\nHow Does Nebivolol 2.5mg and Cilnidipine 10 mg Work?\n\nThis combination targets blood pressure through two complementary mechanisms, making it more effective than single-drug therapy.\n\nMechanism of Action\n1. Nebivolol Action\nBlocks beta-1 adrenergic receptors in the heart\nReduces heart rate and cardiac output\nPromotes release of nitric oxide, improving blood vessel dilation\n2. Cilnidipine Action\nBlocks L-type and N-type calcium channels\nRelaxes blood vessels and reduces resistance\nDecreases stress on blood vessel walls\nCombined Effect\nLowers blood pressure effectively\nImproves blood flow\nReduces strain on the heart\nHelps prevent complications like stroke and heart attack\nKey Benefits of Nebivolol 2.5mg and Cilnidipine 10 mg\n1. Dual Mechanism for Better Control\n\nTargets both heart rate and blood vessel resistance for optimal results.\n\n2. Effective Blood Pressure Reduction\n\nHelps maintain stable blood pressure levels throughout the day.\n\n3. Heart Protection\n\nReduces risk of cardiovascular complications.\n\n4. Improved Tolerability\n\nCombination therapy often leads to fewer side effects compared to higher doses of single drugs.\n\n5. Kidney Protection\n\nCilnidipine helps reduce protein loss in urine, supporting kidney health.\n\nWho Should Consider Buying This Medication?\n\nYou may consider nebivolol 2.5 mg and cilnidipine 10 mg if you:\n\nHave high blood pressure not controlled by a single medicine\nNeed a combination therapy for better results\nAre at risk of heart disease or stroke\nRequire long-term hypertension management\n\nImportant: This medication should only be used under a doctor’s prescription.\n\nDosage and Administration\nRecommended Dosage\nUsually one tablet once daily, or as prescribed\nCan be taken with or without food\nTake at the same time each day for consistency\nUsage Tips\nSwallow the tablet whole with water\nDo not skip doses\nDo not stop suddenly without consulting your doctor\nPossible Side Effects\n\nWhile this combination is generally well tolerated, some side effects may occur.\n\nCommon Side Effects\nHeadache\nDizziness\nFatigue\nSwelling in ankles (edema)\nSlow heart rate\n\nThese are usually mild and temporary.\n\nSerious Side Effects (Rare)\nSevere low blood pressure\nBreathing difficulty\nIrregular heartbeat\nSevere swelling\nAllergic reactions\n\nSeek immediate medical help if you experience serious symptoms.\n\nSafety Precautions Before Buying\nMedical Conditions\n\nInform your doctor if you have:\n\nHeart conditions (e.g., heart block, severe bradycardia)\nLiver or kidney disease\nAsthma or respiratory issues\nDiabetes\nPregnancy & Breastfeeding\nUse only if prescribed\nConsult your doctor before use\nDrug Interactions\n\nThis medication may interact with:\n\nOther blood pressure medicines\nHeart medications\nAntidiabetic drugs\nAlcohol (may increase dizziness)\nWhy Choose Combination Therapy?\n\nCombination medicines like nebivolol 2.5mg and cilnidipine 10 mg are increasingly preferred because they:\n\nProvide better blood pressure control\nReduce the need for multiple medications\nImprove patient compliance\nLower risk of side effects compared to high-dose monotherapy\nPrice in India\n\nThe price of nebivolol 2.5mg and cilnidipine 10 mg tablets in India depends on:\n\nBrand and manufacturer\nPackaging size\nPharmacy location\n\nAlways purchase from a trusted pharmacy or authorized distributor to ensure authenticity.\n\nStorage Instructions\nStore in a cool, dry place\nKeep away from direct sunlight\nKeep out of reach of children\nDo not use expired medicine\nFrequently Asked Questions (FAQs)\n1. What is nebivolol 2.5mg and cilnidipine 10 mg used for?\n\nIt is used to treat high blood pressure and reduce the risk of heart-related complications.\n\n2. Can I take this medicine daily?\n\nYes, but only as prescribed by your doctor.\n\n3. How long does it take to work?\n\nBlood pressure reduction may begin within a few days, with full effects in a few weeks.\n\n4. Is this combination safe?\n\nYes, when used under medical supervision.\n\n5. Can I stop taking it if I feel better?\n\nNo, stopping suddenly may cause blood pressure to rise again.\n\n6. Does it cause swelling?\n\nCilnidipine may cause mild ankle swelling in some patients.\n\nFinal Buying Advice\n\nIf you are looking for a reliable and advanced solution for hypertension, nebivolol 2.5mg and cilnidipine 10 mg is an excellent choice. Before purchasing:\n\nConsult your doctor\nCheck for genuine packaging\nFollow the prescribed dosage\nMonitor your blood pressure regularly\nConclusion\n\nNebivolol 2.5mg and cilnidipine 10 mg is a highly effective combination therapy designed to provide comprehensive blood pressure control while protecting your heart and blood vessels. With its dual mechanism, improved tolerability, and long-term benefits, it is a preferred option for many patients managing hypertension.", "price": 255.0, "discountamount": 76.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2388, "imageuri": "https://productimages.withfloats.com/actual/69e9ed93b34b94774f69ec0b.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/69e9ed93b34b94774f69ec0b.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-04-23T09:59:45.387Z", "updatedon": "2026-04-23T12:38:30.323Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//nebivolol-2-5mg-and-cilnidipine-10-mg/2388", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "NEBIVALVE CILNI 2.5/10", "category": "CARDIOLOGYRANGE", "tags": [ "tab nebivolol 2.5mg", "nebivolol 2.5mg", "nebivolol 2.5mg price", "nebivolol 2.5mg tablet", "tablet nebivolol 2.5mg", "nebivolol 2.5mg and cilnidipine 10 mg", "nebivolol 2.5mg uses", "nebivolol 2.5 mg cilnidipine 10 mg combination benefits", "what is nebivolol 2.5 mg and cilnidipine 10 mg used for", "nebivolol cilnidipine tablets price", "nebivolol 2.5 mg cilnidipine 10 mg supplier india", "nebivolol cilnidipine 2.5/10 tablet brand name", "nebivolol cilnidipine bulk manufacturer", "best price nebivolol cilnidipine tablets", "top quality nebivolol cilnidipine tablets" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69e8b6d9c44d63abc6fde1be", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "paroxetine prolonged release tablets ip", "description": "Paroxetine Prolonged Release Tablets IP\n\nWhen dealing with mental health conditions such as depression, anxiety, or panic disorders, choosing the right medication is crucial for long-term stability and improved quality of life. Paroxetine Prolonged Release Tablets IP is a widely prescribed medication that offers controlled, sustained relief for individuals struggling with various mood and anxiety-related disorders.\n\nThis detailed buyer-intent guide is designed to help patients, caregivers, and healthcare buyers understand the uses, benefits, working mechanism, dosage, and important precautions associated with Paroxetine Prolonged Release Tablets IP.\n\nWhat is Paroxetine Prolonged Release Tablets IP?\n\nParoxetine Prolonged Release Tablets IP contains paroxetine, a selective serotonin reuptake inhibitor (SSRI). It is specifically formulated in a prolonged-release (controlled-release) form, which allows the medication to be released gradually in the body over time.\n\nThis ensures:\n\nStable blood levels of the drug\nReduced dosing frequency\nImproved patient compliance\nFewer fluctuations in therapeutic effect\n\nIt is commonly prescribed for managing a range of psychiatric conditions, including depression and anxiety disorders.\n\nHow Does Paroxetine Prolonged Release Tablets IP Work?\n\nParoxetine works by increasing the levels of serotonin, a neurotransmitter in the brain that plays a key role in mood regulation, emotional balance, and mental well-being.\n\nMechanism of Action:\nBlocks the reabsorption (reuptake) of serotonin in the brain\nEnhances serotonin availability between nerve cells\nImproves communication between neurons\nStabilizes mood and reduces anxiety symptoms\nWhy Prolonged Release Matters:\n\nThe prolonged-release formulation ensures a steady release of medication throughout the day, minimizing side effects and maintaining consistent symptom control.\n\nKey Benefits of Paroxetine Prolonged Release Tablets IP\n1. Effective Treatment for Depression\n\nHelps reduce persistent sadness, low energy, and loss of interest in daily activities.\n\n2. Controls Anxiety Disorders\n\nHighly effective in treating generalized anxiety disorder (GAD), social anxiety, and panic disorder.\n\n3. Improves Emotional Stability\n\nSupports better mood regulation and reduces emotional fluctuations.\n\n4. Once-Daily Convenience\n\nThe prolonged-release formula allows for easy once-daily dosing.\n\n5. Better Tolerability\n\nGradual drug release reduces the risk of sudden side effects compared to immediate-release formulations.\n\nCommon Uses of Paroxetine Prolonged Release Tablets IP\n\nThis medication is prescribed for:\n\nMajor depressive disorder (MDD)\nGeneralized anxiety disorder (GAD)\nPanic disorder\nSocial anxiety disorder\nObsessive-compulsive disorder (OCD)\nPost-traumatic stress disorder (PTSD)\n\nIt is also sometimes used for other conditions based on a doctor’s recommendation.\n\nWho Should Consider Buying Paroxetine Prolonged Release Tablets IP?\n\nThis medication may be suitable for:\n\nIndividuals diagnosed with depression or anxiety disorders\nPatients needing long-term psychiatric management\nThose who prefer once-daily medication for better compliance\nIndividuals who experience side effects with immediate-release SSRIs\n\nImportant: This medication should only be used under a doctor’s prescription and supervision.\n\nDosage and Administration\n\nThe dosage of Paroxetine Prolonged Release Tablets IP depends on the condition being treated and the patient’s response.\n\nGeneral Guidelines:\nTypically taken once daily, usually in the morning\nSwallow the tablet whole with water\nDo not crush, chew, or break the tablet\nDosage Tips:\nStart with a lower dose and increase gradually as advised\nTake the medicine at the same time every day\nDo not skip doses or stop suddenly\nPossible Side Effects\n\nLike all medications, Paroxetine Prolonged Release Tablets IP may cause side effects.\n\nCommon Side Effects:\nNausea\nDrowsiness or fatigue\nDry mouth\nDizziness\nSweating\nLess Common but Serious Side Effects:\nSuicidal thoughts (especially in young adults)\nSevere mood changes\nSerotonin syndrome (rare but serious)\nSexual dysfunction\nWeight changes\n\nIf you experience severe or unusual symptoms, seek medical help immediately.\n\nPrecautions and Warnings\n\nBefore starting this medication, consider the following:\n\nMedical Conditions:\nInform your doctor if you have liver or kidney disease\nPatients with a history of seizures should use caution\nAvoid use in individuals with bipolar disorder without supervision\nPregnancy and Breastfeeding:\nUse only if prescribed\nDiscuss potential risks and benefits with your doctor\nDrug Interactions:\n\nParoxetine may interact with:\n\nMonoamine oxidase inhibitors (MAOIs)\nBlood thinners\nOther antidepressants\nAnti-anxiety medications\n\nAlways inform your healthcare provider about all medications and supplements you are taking.\n\nStorage Instructions\n\nTo maintain effectiveness:\n\nStore in a cool, dry place\nKeep away from direct sunlight\nMaintain temperature below 25°C\nKeep out of reach of children\nBuying Guide: What to Check Before Purchase\n\nWhen purchasing Paroxetine Prolonged Release Tablets IP, ensure the following:\n\nIt is prescribed by a qualified doctor\nThe product is from a trusted pharmaceutical brand\nPackaging is sealed and undamaged\nExpiry date is valid\nPurchased from a licensed pharmacy\n\nFor distributors or bulk buyers, sourcing from reliable manufacturers ensures quality and consistency.\n\nWhy Choose Paroxetine Prolonged Release Tablets IP?\n\nThis medication stands out because of the following:\n\nProven effectiveness in mental health treatment\nControlled-release technology for consistent results\nImproved patient compliance with once-daily dosing\nReduced side effects compared to immediate-release forms\nWidely trusted by healthcare professionals\n\nFor individuals seeking reliable and long-term management of depression and anxiety, this medication is a strong and dependable choice.\n\nFrequently Asked Questions (FAQs)\n1. How long does it take to work?\n\nIt may take 2–4 weeks to notice improvement, with full benefits appearing after several weeks.\n\n2. Can I stop taking it once I feel better?\n\nNo, stopping suddenly can cause withdrawal symptoms. Always consult your doctor.\n\n3. Is it addictive?\n\nNo, but it should be taken as prescribed to avoid dependency-like withdrawal symptoms.\n\n4. Can I take it at night?\n\nIt is usually taken in the morning, but your doctor may adjust timing based on your condition.\n\n5. Does it affect sleep?\n\nIt may cause drowsiness or insomnia in some individuals.\n\nLifestyle Tips for Better Results\n\nTo enhance the effectiveness of Paroxetine:\n\nMaintain a regular sleep schedule\nPractice stress management techniques (yoga, meditation)\nEat a balanced diet\nAvoid alcohol and recreational drugs\nStay physically active\nConclusion\n\nParoxetine Prolonged Release Tablets IP is a highly effective and well-established medication for managing depression, anxiety, and other mental health conditions. Its prolonged-release formulation ensures steady symptom control, improved tolerability, and better patient compliance.\n\nFor best results, always use this medication under medical supervision, follow the prescribed dosage, and combine it with a healthy lifestyle. With the right approach, it can significantly improve emotional well-being and overall quality of life.", "price": 340.0, "discountamount": 102.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2386, "imageuri": "https://productimages.withfloats.com/actual/69e8b716cd1d55c59bd1b04b.png", "tileimageuri": "https://productimages.withfloats.com/tile/69e8b716cd1d55c59bd1b04b.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-04-22T11:54:01.282Z", "updatedon": "2026-05-20T12:03:10.275Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//paroxetine-prolonged-release-tablets-ip/2386", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "PAROXTIME CR 37.5", "category": "NEUROLOGY RANGE", "tags": [ "paroxetine prolonged release tablets", "paroxetine prolonged release tablets uses", "paroxetine prolonged release tablets ip", "paroxetine prolonged release tablets in hindi", "rx paroxetine prolonged release tablets", "paroxetine prolonged release tablets side effects", "use of paroxetine prolonged release tablets", "Paroxetine Prolonged Release Tablets 37.5 mg", "paroxetine prolonged release tablets 37.5 mg price in india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69ba6804c567eee0a8f28929", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "metformin hydrochloride prolonged release and glimepiride tablets", "description": "Managing blood sugar levels effectively is essential for leading a healthy and active life, especially for individuals living with Type 2 Diabetes. With changing lifestyles, unhealthy eating habits, and rising stress levels, diabetes has become increasingly common. To address this, combination therapies like SEIZMET G3 850 offer a powerful and balanced approach to blood sugar control.\n\nThis article provides a detailed, human-friendly, and SEO-optimized guide to Metformin Hydrochloride Prolonged Release and Glimepiride Tablets, marketed under the brand name SEIZMET G3 850.\n\nWhat is SEIZMET G3 850?\n\nSEIZMET G3 850 is a combination anti-diabetic medication that contains:\n\nMetformin Hydrochloride (Prolonged Release) – 850 mg\n\nGlimepiride – 3 mg\n\nThis dual-action formula is designed to control high blood sugar levels in patients with Type 2 Diabetes by targeting different mechanisms in the body.\n\nHow Does SEIZMET G3 850 Work?\n\nThis medicine works through a combination of two powerful components:\n\n1. Metformin (Prolonged Release)\n\nMetformin helps:\n\nReduce glucose production in the liver\n\nImprove insulin sensitivity\n\nEnhance glucose absorption by cells\n\nThe prolonged-release formulation ensures gradual and sustained action, reducing side effects and improving patient compliance.\n\n2. Glimepiride\n\nGlimepiride works by:\n\nStimulating the pancreas to release insulin\n\nImproving the body’s ability to utilize insulin\n\nTogether, these ingredients provide comprehensive blood sugar control throughout the day.\n\nUses of SEIZMET G3 850\n\nSEIZMET G3 850 is primarily used for:\n\n✔ Management of Type 2 Diabetes\n\nIt helps control high blood sugar levels when diet and exercise alone are not sufficient.\n\n✔ Improving Glycemic Control\n\nIt stabilizes blood glucose fluctuations and prevents sudden spikes.\n\n✔ Reducing Risk of Complications\n\nProper diabetes management reduces the risk of:\n\nHeart disease\n\nKidney damage\n\nNerve problems\n\nVision issues\n\nKey Benefits of SEIZMET G3 850\n1. Dual Action Formula\n\nCombines two effective drugs to target diabetes from multiple angles.\n\n2. Sustained Blood Sugar Control\n\nThe prolonged-release metformin ensures steady glucose control throughout the day.\n\n3. Improved Insulin Function\n\nEnhances insulin sensitivity and promotes better glucose utilization.\n\n4. Convenient Dosage\n\nSingle tablet combination reduces pill burden and improves adherence.\n\n5. Weight Neutral Effect\n\nMetformin may help prevent weight gain often associated with diabetes medications.\n\n6. Cardiovascular Protection\n\nHelps reduce the risk of heart-related complications in diabetic patients.\n\nDosage and Administration\n\nAlways take SEIZMET G3 850 as prescribed by your doctor\n\nUsually taken once daily with meals\n\nSwallow the tablet whole—do not crush or chew\n\nMaintain a balanced diet and regular exercise routine\n\nPossible Side Effects\n\nLike all medications, SEIZMET G3 850 may cause side effects, although not everyone experiences them.\n\nCommon Side Effects:\n\nNausea\n\nDiarrhea\n\nStomach discomfort\n\nHeadache\n\nDizziness\n\nThese are usually mild and improve as your body adjusts to the medication.\n\nSerious Side Effects (Rare but Important):\n\nLow blood sugar (hypoglycemia)\n\nLactic acidosis (a rare but serious condition linked to metformin)\n\nAllergic reactions (rash, swelling, itching)\n\nSeek immediate medical attention if you experience severe symptoms.\n\nPrecautions and Warnings\n\nBefore taking SEIZMET G3 850, inform your doctor if you have:\n\nKidney or liver disease\n\nHeart conditions\n\nHistory of alcohol abuse\n\nVitamin B12 deficiency\n\nImportant Tips:\n\nAvoid excessive alcohol consumption\n\nMonitor blood sugar regularly\n\nFollow a diabetic-friendly diet\n\nInform your doctor about other medications\n\nWho Should Avoid This Medicine?\n\nSEIZMET G3 850 may not be suitable for:\n\nPatients with severe kidney disease\n\nIndividuals with Type 1 Diabetes\n\nPregnant or breastfeeding women (unless prescribed)\n\nPeople with known allergies to its components\n\nLifestyle Tips for Better Results\n\nMedication works best when combined with a healthy lifestyle:\n\n✔ Balanced Diet\nInclude:\nWhole grains\nVegetables\n\nLean protein\n\nAvoid sugary and processed foods.\n\n✔ Regular Exercise\n\nAt least 30 minutes of daily activity helps improve insulin sensitivity.\n\n✔ Stress Management\n\nStress can increase blood sugar levels—practice meditation or yoga.\n\n✔ Routine Checkups\n\nRegular monitoring ensures better control and prevents complications.\n\nWhy Choose the SEIZMET G3 850?\n\nChoosing the right medication is crucial in diabetes management. SEIZMET G3 850 stands out because:\n\nIt combines trusted and proven ingredients\n\nOffers long-lasting glucose control\n\nImproves overall metabolic health\n\nSupports a better quality of life\n\nConclusion\nLiving with type 2 diabetes can be challenging, but with the right treatment and lifestyle choices, it can be effectively managed.", "price": 112.0, "discountamount": 34.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2338, "imageuri": "https://productimages.withfloats.com/actual/69ba680714005fb7b0e65883.png", "tileimageuri": "https://productimages.withfloats.com/tile/69ba680714005fb7b0e65883.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-03-18T08:53:24.979Z", "updatedon": "2026-03-18T09:03:56.284Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//metformin-hydrochloride-prolonged-release-and-glimepiride-tablets/2338", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "SEIZMET G3 850", "category": "DIABETIC RANGE", "tags": [ "metformin prolonged release and glimepiride tablets uses", "glimepiride with metformin sr tablets benefits", "metformin hydrochloride pr and glimepiride combination", "metformin sr and glimepiride tablets dosage guide", "glimepiride metformin tablets for type 2 diabetes", "metformin glimepiride combination therapy benefits", "metformin glimepiride tablets for sugar control", "tablets for type 2 diabetes control india", "best medicine for high blood sugar type 2", "combination tablets for diabetes management", "what is metformin hydrochloride prolonged release", "how to control blood sugar with oral tablets", "order metformin glimepiride tablets online india", "glimepiride and metformin tablets manufacturer india", "where to buy diabetes tablets metformin glimepiride", "prescription tablets for type 2 diabetes buy online", "metformin 850 glimepiride 3mg" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6989a63c42154005d2069493", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Citicoline and Piracetam Tablets", "description": "CITICOTIME PM 400 represents a scientifically formulated pharmaceutical combination that brings together two powerful nootropic compounds: Citicoline and Piracetam. This synergistic blend is specifically designed to support cognitive function, enhance mental clarity, and promote overall brain health. Each tablet delivers a precisely calibrated dose of these neurologically active ingredients, making it a preferred choice for individuals seeking to optimize their mental performance, support recovery from neurological conditions, or maintain cognitive vitality as they age.\nThe formulation combines the neuroprotective properties of Citicoline with the cognitive-enhancing effects of Piracetam, creating a comprehensive approach to brain health that addresses multiple pathways of neurological function. This dual-action mechanism makes CITICOTIME PM 400 particularly effective for managing various cognitive challenges and supporting brain function across different age groups and health conditions.\nUnderstanding the Active Ingredients\nCiticoline, also known as CDP-Choline (Cytidine 5'-diphosphocholine), is a naturally occurring compound that plays a crucial role in the synthesis of phosphatidylcholine, a major component of brain cell membranes. This remarkable substance serves as both a choline donor and a source of cytidine, providing the building blocks necessary for maintaining healthy neuronal structures and facilitating efficient neurotransmission.\nPiracetam belongs to the racetam family of nootropics and was one of the first cognitive enhancers ever developed. It works primarily by modulating neurotransmitter systems and enhancing neuroplasticity, the brain's ability to form new connections and adapt to changing demands. Together with Citicoline, it creates a powerful combination that addresses cognitive function from multiple angles.\nPrimary Uses and Indications\nCITICOTIME PM 400 is prescribed for a wide range of neurological and cognitive conditions. It serves as an effective therapeutic intervention for individuals experiencing age-related cognitive decline, helping to slow the progression of memory loss and maintain mental sharpness in older adults. The formulation is particularly valuable for patients recovering from stroke, as it supports neurological rehabilitation and may help restore lost cognitive functions.\nThe medication is also utilized in managing various forms of dementia, including vascular dementia and early-stage Alzheimer's disease, where it helps preserve cognitive abilities and may slow disease progression. Students, professionals, and individuals facing high cognitive demands often use this supplement to enhance focus, concentration, and mental stamina during periods of intensive intellectual work.\nAdditionally, CITICOTIME PM 400 finds application in treating traumatic brain injuries, supporting the recovery process by promoting neuronal repair and protecting against further damage. It's also prescribed for individuals with attention disorders, learning difficulties, and other cognitive impairments that affect daily functioning and quality of life.\nKey Benefits and Therapeutic Advantages\nThe benefits of CITICOTIME PM 400 extend across multiple dimensions of cognitive and neurological health. One of the most significant advantages is enhanced memory formation and recall. The combination of Citicoline and Piracetam supports the mechanisms underlying both short-term and long-term memory, making it easier to learn new information and retrieve stored memories when needed.\nImproved focus and concentration represent another cornerstone benefit. Users often report experiencing sustained attention spans, reduced mental fatigue, and an enhanced ability to engage in complex tasks requiring prolonged cognitive effort. This makes the supplement particularly valuable for individuals whose work or studies demand high levels of mental performance.\nThe formulation provides robust neuroprotective effects, shielding brain cells from oxidative stress, inflammation, and age-related deterioration. This protective action helps maintain the structural integrity of neurons and supports long-term brain health, potentially reducing the risk of neurodegenerative conditions.\nEnhanced cerebral blood flow is another critical benefit. Both active ingredients work to improve circulation within the brain, ensuring that neurons receive adequate oxygen and nutrients while facilitating the removal of metabolic waste products. This improved circulation contributes to better overall brain function and mental clarity.\nUsers frequently experience increased mental energy and reduced brain fog. The supplement helps combat the mental sluggishness that can accompany aging, stress, or illness, promoting a state of alert wakefulness and mental clarity throughout the day.\nThe formulation also supports neuroplasticity and cognitive flexibility, enabling the brain to adapt more readily to new challenges, learn new skills more efficiently, and recover more effectively from neurological insults.\nPotential Side Effects and Considerations\nWhile CITICOTIME PM 400 is generally well-tolerated by most users, it's important to be aware of potential side effects. Common mild effects may include headaches, particularly during the initial days of treatment as the body adjusts to the medication. Some individuals may experience digestive disturbances such as nausea, stomach upset, or mild gastrointestinal discomfort.\nSleep disturbances, including insomnia or vivid dreams, can occur in some users, particularly if the medication is taken too late in the day. To minimize this risk, it's typically recommended to take CITICOTIME PM 400 in the morning or early afternoon.\nOther potential side effects include nervousness, restlessness, or mild anxiety in sensitive individuals. Some users may experience dizziness, particularly when standing up quickly. Rarely, individuals may report skin rashes or allergic reactions, which should prompt immediate medical consultation.\nIt's crucial to inform your healthcare provider about all medications, supplements, and health conditions before starting CITICOTIME PM 400, as interactions may occur with certain drugs, particularly blood thinners and other neurological medications.\nDosage and Administration Guidelines\nThe typical dosage and administration schedule should always be determined by a qualified healthcare professional based on individual needs, health status, and treatment objectives. Generally, the medication is taken orally with water, preferably with meals to enhance absorption and minimize gastrointestinal side effects.\nConsistency in timing is important for maintaining stable blood levels of the active ingredients. Most prescribers recommend taking the supplement in the morning or early afternoon to avoid potential sleep interference. It's advisable to avoid taking CITICOTIME PM 400 on an empty stomach, as this may increase the likelihood of digestive discomfort.\nConclusion\nCITICOTIME PM 400 stands as a scientifically-backed, comprehensive cognitive enhancement solution that addresses brain health through multiple complementary mechanisms. The intelligent combination of Citicoline and Piracetam offers users a powerful tool for maintaining cognitive vitality, supporting recovery from neurological challenges, and optimizing mental performance across various life stages.", "price": 780.0, "discountamount": 234.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2296, "imageuri": "https://productimages.withfloats.com/actual/6989a63f3821a38d68f07a39.png", "tileimageuri": "https://productimages.withfloats.com/tile/6989a63f3821a38d68f07a39.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-02-09T09:17:48.921Z", "updatedon": "2026-05-23T07:23:00.607Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//citicoline-and-piracetam-tablets/2296", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CITICOTIME PM 400", "category": "NEUROLOGY RANGE", "tags": [ "citicoline and piracetam tablets uses", "citicoline and piracetam combination tablets", "citicoline piracetam tablets for brain health", "how citicoline and piracetam tablets work", "citicoline piracetam tablets benefits", "citicoline piracetam tablets side effects", "citicoline piracetam oral tablets", "citicoline piracetam tablet composition", "citicoline piracetam tablets for memory improvement", "citicoline piracetam tablets for cognitive impairment", "what are citicoline and piracetam tablets", "who should take citicoline piracetam tablets", "how long does citicoline piracetam take to work", "citicoline with piracetam tablets", "piracetam citicoline brain supplement tablets", "citicoline piracetam nootropic combination", "citicoline and piracetam tablets price", "citicoline and piracetam tablets uses in hindi", "citicoline and piracetam tablets uses in tamil", "citicoline and piracetam tablets brands", "citicoline and piracetam tablets side effects", "use of citicoline and piracetam tablets", "citicoline and piracetam tablets dosage", "citicoline and piracetam tablets uses in telugu", "citicoline and piracetam tablets uses in english", "citicoline and piracetam tablets use" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69623e6c95697555dd1afd67", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Esomeprazole and Itopride", "description": "ESMOSTRUM IT: Comprehensive Product Guide\nProduct Overview\nESMOSTRUM IT is an advanced pharmaceutical formulation that combines two potent active ingredients—Esomeprazole and Itopride—to provide comprehensive relief from gastrointestinal disorders. This dual-action medication represents a significant advancement in the management of acid-related digestive conditions and motility disorders. By combining a proton pump inhibitor with a prokinetic agent, ESMOSTRUM IT addresses both the underlying causes and symptomatic manifestations of various digestive ailments, offering patients a complete therapeutic solution in a single, convenient dosage form.\nThe synergistic combination of Esomeprazole and Itopride makes ESMOSTRUM IT particularly effective for individuals suffering from gastroesophageal reflux disease (GERD), functional dyspepsia, and other conditions where both excessive acid production and impaired gastric motility contribute to discomfort and disease progression.\nActive Pharmaceutical Ingredients\nEsomeprazole\nEsomeprazole is the S-isomer of omeprazole and belongs to the class of medications known as proton pump inhibitors (PPIs). It works by specifically and irreversibly blocking the hydrogen-potassium adenosine triphosphatase enzyme system (the proton pump) located in the gastric parietal cells. This mechanism effectively reduces gastric acid secretion, providing sustained relief from acid-related symptoms and allowing damaged esophageal and gastric tissue to heal.\nItopride\nItopride is a prokinetic agent that enhances gastrointestinal motility through a dual mechanism of action. It acts as both a dopamine D2 receptor antagonist and an acetylcholinesterase inhibitor. By blocking dopamine receptors, it removes the inhibitory effect of dopamine on gastrointestinal motility, while its acetylcholinesterase inhibition increases acetylcholine levels, further promoting coordinated gastric contractions and improved gastric emptying.\nTherapeutic Uses and Indications\nESMOSTRUM IT is prescribed for a wide range of gastrointestinal conditions where both acid suppression and enhanced motility are therapeutically beneficial:\nGastroesophageal Reflux Disease (GERD)\nESMOSTRUM IT provides exceptional relief for patients suffering from GERD, a chronic condition where stomach acid frequently flows back into the esophagus. The esomeprazole component reduces acid production, while itopride improves the tone of the lower esophageal sphincter and accelerates gastric emptying, thereby reducing the frequency and severity of reflux episodes.\nFunctional Dyspepsia\nFor patients experiencing persistent or recurrent upper abdominal discomfort without an identifiable organic cause, ESMOSTRUM IT addresses multiple pathophysiological mechanisms. It relieves symptoms such as early satiety, postprandial fullness, epigastric pain, and bloating by normalizing gastric acid levels and improving gastric accommodation and emptying.\nPeptic Ulcer Disease\nESMOSTRUM IT aids in the healing of gastric and duodenal ulcers by creating an optimal healing environment through sustained acid suppression. The prokinetic action of itopride helps prevent stasis of gastric contents, which can exacerbate ulcer symptoms.\nNon-Ulcer Dyspepsia\nMany patients experience dyspeptic symptoms without evidence of ulceration. ESMOSTRUM IT effectively manages these symptoms by addressing both acid hypersecretion and delayed gastric emptying, two key factors in non-ulcer dyspepsia.\nGastroparesis-Related Symptoms\nIn conditions where gastric emptying is significantly delayed, the itopride component of ESMOSTRUM IT helps restore more normal gastric motility patterns, reducing associated symptoms like nausea, vomiting, and abdominal distension.\nKey Benefits and Advantages\nDual Mechanism of Action\nThe primary advantage of ESMOSTRUM IT lies in its comprehensive approach to gastrointestinal health. Rather than addressing only acid production or motility in isolation, this combination therapy tackles both aspects simultaneously, providing more complete symptom relief and better therapeutic outcomes.\nSuperior Acid Suppression\nEsomeprazole offers more consistent and prolonged acid suppression compared to many other acid-reducing medications. It provides sustained relief throughout the day and night, allowing patients to experience fewer breakthrough symptoms and better quality of life.\nEnhanced Gastric Motility\nThe itopride component specifically targets motility issues without crossing the blood-brain barrier significantly, meaning it provides prokinetic benefits with minimal central nervous system side effects. This results in improved gastric emptying, reduced bloating, and decreased feelings of fullness after meals.\nRapid Symptom Relief\nMany patients experience noticeable improvement in their symptoms within the first few days of treatment with ESMOSTRUM IT. The combination therapy addresses multiple symptom pathways simultaneously, leading to faster and more comprehensive relief.\nImproved Quality of Life\nBy effectively managing symptoms such as heartburn, regurgitation, nausea, bloating, and early satiety, ESMOSTRUM IT significantly enhances patients' daily functioning and overall well-being. Patients report better sleep quality, improved dietary tolerance, and reduced anxiety related to their digestive symptoms.\nConvenient Dosing\nThe combination of two active ingredients in a single formulation improves medication adherence by reducing pill burden. Patients appreciate the simplicity of taking one medication instead of multiple separate preparations.\nMucosal Healing Properties\nBeyond symptom relief, ESMOSTRUM IT promotes actual healing of damaged esophageal and gastric mucosa. The reduced acid environment created by esomeprazole allows inflamed and eroded tissue to regenerate properly.\nReduced Risk of Complications\nBy effectively controlling acid reflux and improving gastric emptying, ESMOSTRUM IT helps prevent potential complications of chronic GERD, such as esophageal strictures, Barrett's esophagus, and respiratory complications from aspiration.\nDosage and Administration\nESMOSTRUM IT should be taken exactly as prescribed by a healthcare professional. Typically, the medication is administered orally, preferably before meals to optimize its therapeutic effects. The standard dosing regimen usually involves once or twice daily administration, though individual requirements may vary based on the severity of the condition and patient response.\nThe medication should be swallowed whole with water and should not be crushed, chewed, or split, as this may affect the drug's release mechanism and therapeutic efficacy. Patients should maintain regular dosing schedules to ensure optimal acid suppression and motility enhancement throughout the day.\nSide Effects and Safety Considerations\nLike all medications, ESMOSTRUM IT may cause side effects in some individuals, though not everyone experiences them. Understanding potential adverse effects helps patients identify and report concerning symptoms promptly.\nCommon Side Effects\nGastrointestinal Effects: Some patients may experience diarrhea, constipation, abdominal pain, nausea, or flatulence, particularly during initial treatment. These effects are usually mild and often resolve as the body adjusts to the medication.\nHeadache: Mild to moderate headaches occur in a small percentage of patients and typically diminish with continued use.\nDizziness: Some individuals may experience lightheadedness or dizziness, particularly when standing up quickly.\nDry Mouth: Reduced saliva production may occur, leading to oral dryness and discomfort.\nLess Common Side Effects\nSkin Reactions: Rash, itching, or other dermatological manifestations may develop in sensitive individuals.\nSleep Disturbances: Some patients report insomnia or unusual dreams while taking the medication.\nIncreased Prolactin Levels: Itopride may cause mild elevation in prolactin levels, though clinical manifestations are rare.\nTaste Alterations: Changes in taste perception or metallic taste may occur temporarily.\nSerious Side Effects (Rare)\nWhile uncommon, certain serious adverse effects require immediate medical attention:\n\nSevere allergic reactions including difficulty breathing, facial swelling, or severe skin reactions\nSevere diarrhea that persists or contains blood\nIrregular heartbeat or palpitations\nMuscle weakness or pain\nSeizures or tremors\nSigns of liver problems including jaundice, dark urine, or persistent nausea\n\nLong-Term Considerations\nExtended use of proton pump inhibitors like esomeprazole has been associated with certain risks that patients should discuss with their healthcare providers:\n\nPotential reduction in calcium, magnesium, and vitamin B12 absorption\nSlightly increased risk of bone fractures with prolonged use\nPossible increased susceptibility to certain gastrointestinal infections\nRare cases of kidney problems\n\nRegular monitoring and periodic assessment by healthcare professionals help minimize these risks while maintaining therapeutic benefits.\nPrecautions and Contraindications\nPatients should inform their healthcare provider about all existing medical conditions, particularly liver disease, kidney problems, osteoporosis, low magnesium levels, or any gastrointestinal bleeding. ESMOSTRUM IT may interact with certain medications, including blood thinners, antifungals, HIV medications, and certain antibiotics. A complete medication review ensures safe and effective therapy.\nPregnant or breastfeeding women should only use ESMOSTRUM IT under strict medical supervision, as the safety profile in these populations requires careful consideration of potential risks and benefits.\nLifestyle Recommendations\nFor optimal therapeutic outcomes, patients taking ESMOSTRUM IT should complement their medication regimen with appropriate lifestyle modifications:\n\nAvoid trigger foods that exacerbate acid reflux, such as spicy foods, citrus, chocolate, caffeine, and alcohol\nMaintain a healthy body weight to reduce abdominal pressure\nEat smaller, more frequent meals rather than large portions\nAvoid lying down immediately after eating; wait at least two to three hours\nElevate the head of the bed if nighttime symptoms occur\nQuit smoking, as tobacco use significantly worsens reflux symptoms\nManage stress through relaxation techniques, as stress can exacerbate digestive symptoms\n\nConclusion\nESMOSTRUM IT represents a sophisticated and effective pharmaceutical solution for individuals struggling with complex gastrointestinal disorders involving both acid hypersecretion and impaired motility. By combining the powerful acid-suppressing capabilities of esomeprazole with the prokinetic benefits of itopride, this medication offers comprehensive symptom management that addresses the multifaceted nature of digestive disorders.", "price": 182.0, "discountamount": 54.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2273, "imageuri": "https://productimages.withfloats.com/actual/69623e6fd8491171373812e3.png", "tileimageuri": "https://productimages.withfloats.com/tile/69623e6fd8491171373812e3.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-10T11:56:28.061Z", "updatedon": "2026-04-21T09:38:56.999Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//esomeprazole-and-itopride/2273", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ESMOSTRUM IT", "category": "GASTROLOGYRANGE", "tags": [ "esomeprazole and itopride", "esomeprazole and itopride capsules uses in hindi", "esomeprazole and itopride capsules uses", "esomeprazole and itopride brand name", "esomeprazole and itopride hydrochloride", "esomeprazole and itopride capsules", "esomeprazole and itopride uses", "esomeprazole and itopride hydrochloride capsules", "esomeprazole and itopride hydrochloride uses", "esomeprazole and itopride hydrochloride price", "esomeprazole and itopride hydrochloride price in india", "buy online Esomeprazole and Itopride" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "694cf85408591c1173b54c2f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Pregabalin Epalrestat and Methylcobalamin Tablets", "description": "EPSTATE ED represents an advanced pharmaceutical formulation that combines three powerful therapeutic agents: Pregabalin, Epalrestat, and Methylcobalamin. This innovative triple-combination medication is specifically designed to address the complex pathophysiology of diabetic neuropathy and neuropathic pain conditions. By integrating multiple mechanisms of action, EPSTATE ED offers a comprehensive approach to managing nerve-related complications that significantly impact the quality of life for millions of individuals worldwide.\nThe formulation addresses not only the symptomatic relief of neuropathic pain but also targets the underlying metabolic derangements that contribute to nerve damage progression. This multi-pronged therapeutic strategy makes EPSTATE ED particularly valuable for patients who require more than symptomatic management alone.\nUnderstanding the Active Components\nPregabalin: The Neuropathic Pain Modulator\nPregabalin serves as the cornerstone analgesic component in EPSTATE ED. This anticonvulsant medication works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. Through this mechanism, Pregabalin reduces the release of excitatory neurotransmitters including glutamate, norepinephrine, and substance P. This reduction in neurotransmitter release effectively dampens the abnormal neural signaling that characterizes neuropathic pain conditions.\nThe molecule demonstrates excellent bioavailability and rapid absorption, allowing patients to experience relief within a relatively short timeframe. Its efficacy in managing various neuropathic pain syndromes has been extensively documented in clinical trials, establishing it as a first-line agent for diabetic peripheral neuropathy, postherpetic neuralgia, and other chronic neuropathic pain conditions.\nEpalrestat: The Aldose Reductase Inhibitor\nEpalrestat represents a unique addition to the formulation, functioning as a selective aldose reductase inhibitor. In diabetic conditions, excess glucose is converted to sorbitol through the polyol pathway, with aldose reductase serving as the rate-limiting enzyme. The accumulation of sorbitol within nerve cells leads to osmotic stress, depletion of myoinositol, and subsequent nerve dysfunction.\nBy inhibiting aldose reductase, Epalrestat prevents this harmful sorbitol accumulation, thereby addressing one of the fundamental metabolic abnormalities responsible for diabetic neuropathy. This disease-modifying approach distinguishes EPSTATE ED from purely symptomatic treatments. Epalrestat has been particularly well-studied in Asian populations and has demonstrated the ability to improve nerve conduction velocities and reduce subjective neuropathic symptoms over time.\nMethylcobalamin: The Neurotropic Vitamin\nMethylcobalamin, the bioactive form of Vitamin B12, completes the therapeutic triad in EPSTATE ED. Unlike cyanocobalamin, which requires conversion in the body, methylcobalamin is immediately available for utilization in crucial biochemical processes. It plays an indispensable role in myelin synthesis, the protective sheath surrounding nerve fibers that enables proper signal transmission.\nThis coenzyme participates in methionine synthesis and is essential for maintaining the structural and functional integrity of neurons. Methylcobalamin also facilitates nerve regeneration and has demonstrated neuroprotective properties in various experimental models. For patients with diabetic neuropathy, who often exhibit Vitamin B12 deficiency (sometimes exacerbated by metformin therapy), supplementation with methylcobalamin addresses both nutritional deficits and supports nerve health at a fundamental level.\nClinical Applications and Uses\nEPSTATE ED is primarily indicated for the comprehensive management of diabetic peripheral neuropathy, a condition affecting approximately 50% of individuals with long-standing diabetes. The symptoms of this condition range from tingling sensations and burning pain to numbness and loss of protective sensation, which can lead to serious complications including foot ulcers and amputations.\nBeyond diabetic neuropathy, EPSTATE ED may be prescribed for various neuropathic pain syndromes where the combination of pain relief, metabolic correction, and nerve support proves beneficial. Patients experiencing chronic nerve pain resulting from metabolic disturbances, nutritional deficiencies, or structural nerve damage may find this combination particularly effective.\nThe medication is typically recommended for adults who have not achieved adequate symptom control with single-agent therapy or who would benefit from the synergistic effects of the three components. Healthcare providers may prescribe EPSTATE ED when a patient requires both immediate symptom relief and long-term disease modification.\nKey Benefits and Therapeutic Advantages\nComprehensive Multi-Mechanism Action\nThe primary advantage of EPSTATE ED lies in its multi-faceted approach to neuropathic conditions. Rather than addressing only pain symptoms, the formulation simultaneously tackles pain perception, underlying metabolic abnormalities, and nutritional support for nerve health. This comprehensive strategy may lead to superior outcomes compared to monotherapy approaches.\nEnhanced Pain Relief\nClinical evidence supporting Pregabalin's efficacy in neuropathic pain is substantial. Patients often report significant reductions in pain intensity, improved sleep quality due to decreased nocturnal pain, and enhanced ability to perform daily activities. The pain-relieving effects typically manifest within the first week of therapy and continue to improve with ongoing treatment.\nDisease Modification Potential\nUnlike purely symptomatic treatments, the inclusion of Epalrestat provides genuine disease-modifying potential. By targeting the polyol pathway, EPSTATE ED may slow the progression of nerve damage in diabetic patients. Long-term use may preserve nerve function and prevent the worsening of neuropathic symptoms, offering hope beyond mere symptom management.\nImproved Nerve Conduction and Function\nThe combination of metabolic correction through Epalrestat and neurotropic support via Methylcobalamin creates an environment conducive to nerve regeneration and functional improvement. Studies have demonstrated improvements in nerve conduction velocity parameters with similar combination therapies, suggesting potential restoration of nerve function rather than simple symptom masking.\nConvenience of Combination Therapy\nFor patients who would otherwise require multiple separate medications, EPSTATE ED offers the convenience of a single tablet containing all three therapeutic agents. This simplification of medication regimens improves compliance, reduces pill burden, and may enhance overall treatment outcomes.\nQuality of Life Enhancement\nThe cumulative effect of pain reduction, improved nerve function, and better metabolic control translates into meaningful quality of life improvements. Patients report better mobility, reduced interference of pain with daily activities, improved mood, and enhanced social functioning.\nPotential Side Effects and Safety Considerations\nCommon Side Effects\nAs with any pharmaceutical agent, EPSTATE ED may produce certain adverse effects. The most commonly reported side effects are primarily attributable to the Pregabalin component and include dizziness, somnolence, peripheral edema, dry mouth, blurred vision, weight gain, and difficulty with concentration or attention. These effects are generally mild to moderate and often diminish with continued therapy as the body adapts to the medication.\nGastrointestinal symptoms such as constipation or nausea may occur, though they are typically manageable with dietary modifications or symptomatic treatment. Some patients experience increased appetite leading to weight gain, which requires monitoring, particularly in diabetic individuals where weight management is crucial.\nSerious but Rare Adverse Events\nThough uncommon, certain serious adverse effects warrant immediate medical attention. These include allergic reactions manifesting as rash, itching, swelling, severe dizziness, or breathing difficulties. Pregabalin has been associated with rare cases of angioedema, which requires prompt discontinuation and medical intervention.\nMental health changes, including mood alterations, anxiety, depression, agitation, or suicidal thoughts, have been reported with Pregabalin use, particularly in individuals with pre-existing psychiatric conditions. Patients and caregivers should remain vigilant for behavioral changes and report them immediately to healthcare providers.\nDrug Interactions and Precautions\nEPSTATE ED may interact with other central nervous system depressants, including alcohol, opioids, benzodiazepines, and antihistamines, potentially intensifying sedation and cognitive impairment. Patients should inform their healthcare provider of all medications, supplements, and substances they consume.\nIndividuals with kidney impairment require dose adjustments since Pregabalin is primarily eliminated through renal excretion. Regular monitoring of renal function may be necessary during long-term therapy.\nSpecial Population Considerations\nPregnant or breastfeeding women should use EPSTATE ED only when clearly necessary and under strict medical supervision, as the safety profile in these populations has not been fully established. Elderly patients may be more susceptible to side effects, particularly dizziness and confusion, necessitating careful dose titration and monitoring.\nPatients should be advised against abrupt discontinuation of EPSTATE ED, as sudden cessation of Pregabalin may precipitate withdrawal symptoms including insomnia, nausea, headache, anxiety, and sweating. Gradual dose reduction under medical supervision is recommended when discontinuing therapy.\nDosage and Administration Guidelines\nThe appropriate dosage of EPSTATE ED is highly individualized and should be determined by a qualified healthcare professional based on the patient's specific condition, response to therapy, and tolerance. Typically, treatment begins with a lower dose that is gradually increased to achieve optimal therapeutic benefit while minimizing adverse effects.\nPatients should take EPSTATE ED exactly as prescribed, with or without food, at consistent times each day to maintain stable blood levels. Missing doses should be addressed by taking the forgotten dose as soon as remembered, unless it's nearly time for the next scheduled dose. Double dosing to compensate for missed doses is not recommended.\nRegular follow-up appointments allow healthcare providers to assess treatment efficacy, monitor for adverse effects, and make necessary dose adjustments. Patients should maintain open communication with their medical team regarding symptom improvement, side effects, and any concerns that arise during therapy.\nPatient Counseling and Lifestyle Recommendations\nMaximizing the benefits of EPSTATE ED extends beyond simply taking the medication. Patients should be counseled on complementary lifestyle measures that support neuropathy management. Maintaining optimal glycemic control remains paramount for diabetic patients, as blood sugar management directly impacts neuropathy progression regardless of medication.\nRegular physical activity, within individual capabilities, promotes circulation, supports nerve health, and may enhance the therapeutic effects of EPSTATE ED. Daily foot examinations become critical for diabetic patients to identify potential injuries early, preventing serious complications.\nNutritional optimization, including adequate intake of B vitamins, antioxidants, and essential nutrients, supports the neurotropic effects of Methylcobalamin. Avoiding alcohol and tobacco, both of which can exacerbate neuropathy, is strongly recommended.\nPatients should be cautioned about activities requiring alertness, such as driving or operating machinery, especially during the initial treatment phase when dizziness and somnolence may be more pronounced. These effects typically improve with continued therapy, but individual responses vary.\nConclusion\nEPSTATE ED represents a thoughtfully designed pharmaceutical formulation that addresses the multifaceted nature of diabetic neuropathy and neuropathic pain through its unique combination of Pregabalin, Epalrestat, and Methylcobalamin. This triple-action approach offers patients more than symptomatic relief—it provides genuine disease modification potential, nutritional support, and comprehensive nerve health optimization.\nThe synergistic effects of these three components create a therapeutic profile that is greater than the sum of its parts. While Pregabalin efficiently manages pain symptoms and improves quality of life in the short term, Epalrestat works to address underlying metabolic derangements that drive disease progression, and Methylcobalamin provides essential neurotropic support for nerve regeneration and function.\nFor patients struggling with the debilitating effects of neuropathic pain and diabetic neuropathy, EPSTATE ED offers renewed hope for better symptom control and potentially slowed disease progression. The convenience of combination therapy in a single tablet improves adherence and simplifies complex treatment regimens.\nHowever, EPSTATE ED is not without considerations. Potential side effects, though generally manageable, require awareness and monitoring. The medication is most effective when integrated into a comprehensive management plan that includes optimal glycemic control, lifestyle modifications, and regular medical supervision.\nUltimately, EPSTATE ED should be viewed as a valuable tool in the therapeutic arsenal against neuropathic conditions, best utilized under the guidance of knowledgeable healthcare professionals who can individualize treatment to each patient's unique needs and circumstances. With proper use, monitoring, and patient education, EPSTATE ED can significantly improve outcomes and quality of life for those affected by these challenging neurological conditions.", "price": 275.0, "discountamount": 82.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2253, "imageuri": "https://productimages.withfloats.com/actual/694cf859d25fa0b0657b1ac8.png", "tileimageuri": "https://productimages.withfloats.com/tile/694cf859d25fa0b0657b1ac8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-25T08:39:48.947Z", "updatedon": "2026-04-18T09:21:49.885Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//pregabalin-epalrestat-and-methylcobalamin-tablets/2253", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "EPSTATE ED", "category": "NEUROLOGYRANGE", "tags": [ "regabalin, Epalrestat, and Methylcobalamin.neuropathic pain conditions.", "Pregabalin, Epalrestat, and Methylcobalamin.", "neuropathic pain.", "diabetic neuropathy.", "sorbitol within nerve cells leads to osmotic stress.", "Epalrestat and neurotropic support via Methylcobalamin creates an environment .", "mood alterations, anxiety, depression, agitation.", "supports the neurotropic effects of Methylcobalamin.", "Pregabalin Epalrestat and Methylcobalamin Tablets", "epalrestat and methylcobalamin tablets uses", "epalrestat and methylcobalamin tablets in hindi", "pregabalin epalrestat and methylcobalamin tablets price jaipur", "pregabalin epalrestat and methylcobalamin tablets price india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "691b17834c6b1fd261aeaae2", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Dothiepin 75mg and Methylcobalamin 1500mcg | DROTHEPINE M 75", "description": "DROTHEPINE M 75 is a clinically formulated combination that unites the therapeutic strength of Dothiepin 75mg, a tricyclic antidepressant, with Methylcobalamin 1500 mcg, an essential neurovitamin known for its nerve-repairing properties. This high-strength formulation is designed to support individuals facing depression, anxiety, neuropathic pain, and nerve degeneration associated with vitamin B12 deficiency. Dothiepin works by restoring chemical balance in the brain to improve mood, sleep, and emotional well-being. Meanwhile, Methylcobalamin helps repair damaged nerves and enhances nerve conduction. Together, these components make DROTHEPINE M 75 a comprehensive solution for boosting both mental health and neurological function.\n\nUses\nDROTHEPINE M 75 is recommended for the treatment and management of several psychological and nerve-related conditions. Its primary uses include:\nTreatment of Major Depression and Anxiety Disorders: Helps reduce persistent sadness, irritability, and emotional instability.\n\nManagement of Neuropathic Pain: Effective for nerve pain caused by diabetes, injuries, and chronic nerve damage.\n\nCorrection of Vitamin B12 Deficiency: Supports proper nerve functioning in individuals with low B12 levels.\n\nRelief from Nerve Tingling, Burning, and Numbness: Ideal for managing peripheral neuropathy symptoms.\n\nSupport for Sleep Disturbances Linked to Stress or Depression: Promotes relaxation and improves sleep quality.\n\nThese multifaceted uses make DROTHEPINE M 75 a trusted choice for patients needing both emotional and neurological support.\n\nBenefits\n\nThe powerful combination of Dothiepin 75mg and Methylcobalamin 1500mcg delivers a wide range of therapeutic benefits:\n\n1. Enhanced Mood Regulation\n\nDothiepin helps restore the balance of neurotransmitters like serotonin and norepinephrine, providing relief from depression and anxiety while enhancing overall emotional stability.\n\n2. Supports Nerve Regeneration\n\nMethylcobalamin promotes nerve cell repair, improves nerve signaling, and helps reduce neuropathic pain more effectively than standard B12 forms.\n\n3. Dual Action for Mental and Nerve Health\n\nBy targeting both emotional and physical discomfort, DROTHEPINE M 75 offers holistic relief, making daily life more manageable.\n\n4. Improved Sleep and Cognitive Clarity\n\nThe antidepressant component reduces stress-related sleep disturbances and supports improved focus, concentration, and memory.\n\n5. Best-in-Class Strength for Long-Lasting Relief\n\nWith a higher 75mg dose of Dothiepin, this formulation provides sustained action throughout the day, delivering dependable symptom control.\n\nDosage\n\nThe typical recommended dosage of DROTHEPINE M 75 is one tablet once daily, or as directed by a healthcare professional.\n\nTake the tablet with water, preferably after meals to reduce gastrointestinal discomfort.\n\nDosage may differ based on individual needs, severity of symptoms, and medical history.\n\nConsistency is key—take the medication at the same time each day for optimal results.\n\nDo not increase, reduce, or stop the dosage abruptly without consulting a doctor.\n\nSide Effects\n\nAlthough DROTHEPINE M 75 is generally well-tolerated, some individuals may experience mild side effects, especially at the beginning of treatment. These may include:\n\nDrowsiness or dizziness\n\nDry mouth\n\nConstipation\n\nBlurred vision\n\nFatigue or tiredness\n\nIncreased appetite or weight changes\n\nMild nausea or headache\n\nSevere side effects are uncommon, but seek immediate medical attention if you experience irregular heartbeat, severe dizziness, allergic reactions, or sudden mood changes.\n\nPrecautions and Warning\n\nAvoid alcohol while taking this medication, as it may intensify drowsiness and impair alertness.\n\nNot recommended during pregnancy or breastfeeding unless prescribed by a healthcare provider.\n\nPeople with heart problems, glaucoma, epilepsy, liver disease, or urinary retention must inform their doctor before use.\n\nThis medicine may cause drowsiness—avoid driving or operating machinery until you know how it affects you.\n\nDo not discontinue the medicine abruptly; dosage reduction should be supervised by a doctor.\n\nKeep the medication stored in a cool, dry place away from children.\n\nConclusion\n\nDROTHEPINE M 75, formulated with Dothiepin 75mg and Methylcobalamin 1500 mcg, is an advanced dual-action therapy designed to support emotional well-being and nerve health simultaneously. It effectively treats depression, anxiety, neuropathic pain, and vitamin B12 deficiency while promoting nerve repair and cognitive clarity. When taken under medical supervision, this powerful combination helps restore balance, reduce discomfort, and improve your overall quality of life.", "price": 360.0, "discountamount": 108.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2209, "imageuri": "https://productimages.withfloats.com/actual/691b1786743983a7e3b55dc4.png", "tileimageuri": "https://productimages.withfloats.com/tile/691b1786743983a7e3b55dc4.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-17T12:39:31.538Z", "updatedon": "2026-05-20T11:51:33.395Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//dothiepin-75mg-and-methylcobalamin-1500mcg-drothepine-m-75/2209", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "DROTHEPINE M 75", "category": "NEUROLOGYRANGE", "tags": [ "DROTHEPINE M 75", "Depression and Anxiety Disorders", "Dothiepin 75mg", "Methylcobalamin 1500 mcg", "neuropathic pain", "dothiepin 75mg methylcobalamin 1500mcg benefits for nerve pain", "how dothiepin 75mg with methylcobalamin 1500mcg works for depression", "dothiepin methylcobalamin combination uses and side effects in India", "methylcobalamin 1500mcg with dothiepin for neuropathic pain relief", "methylcobalamin 1500mcg dothiepin combo cost in India", "is dothiepin 75mg with methylcobalamin 1500mcg safe?", "how to take dothiepin and methylcobalamin combination", "side effects of dothiepin 75mg with methylcobalamin 1500mcg", "methylcobalamin 1500mcg dosage for nerve pain" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69142bf71d499513a92e5772", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nicorandil Tablets 5mg", "description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.", "price": 381.0, "discountamount": 115.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2202, "imageuri": "https://productimages.withfloats.com/actual/69142c03b53db80943abd33d.png", "tileimageuri": "https://productimages.withfloats.com/tile/69142c03b53db80943abd33d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T06:40:55.795Z", "updatedon": "2026-03-16T08:18:00.245Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//nicorandil-tablets-5mg/2202", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MAYORANDIL 5 ", "category": "CARDIOLOGYRANGE", "tags": [ "nicorandil tablets 5mg", "nicorandil 5 mg tablets uses", "nicorandil tablet 5mg benefits", "nicorandil 5mg medicine", "nicorandil tablets ip 5 mg", "what is nicorandil 5mg used for", "how does nicorandil tablet work", "nicorandil 5mg mechanism of action", "nicorandil tablets for angina treatment", "nicorandil tablet uses in heart disease", "nicorandil 5mg tablet price in india", "buy nicorandil 5mg tablets online", "nicorandil 5mg tablet brands", "nicorandil tablets manufacturer", "nicorandil tablets wholesale supplier" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }