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{ "products": [ { "_id": "6961f2c52800555f6696ac8f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Sitagliptin Phosphate 100 mg", "description": "GLISITAPTIN 100 is a pharmaceutical formulation containing Sitagliptin Phosphate 100 mg as its active ingredient. This medication represents a significant advancement in the management of type 2 diabetes mellitus, offering patients an effective oral treatment option that works through an innovative mechanism of action. As part of the DPP-4 inhibitor class of antidiabetic medications, GLISITAPTIN 100 has emerged as a trusted choice for healthcare providers and patients seeking reliable glycemic control with a favorable safety profile.\nThe brand name GLISITAPTIN 100 signifies quality, efficacy, and a commitment to helping individuals with type 2 diabetes achieve better health outcomes. Each tablet is precisely formulated to deliver the optimal therapeutic dose of sitagliptin phosphate, ensuring consistent and predictable results in blood sugar management.\nUnderstanding Sitagliptin Phosphate\nSitagliptin phosphate is a highly selective dipeptidyl peptidase-4 (DPP-4) inhibitor that has revolutionized diabetes treatment since its introduction. Unlike older diabetes medications that work through insulin secretion or glucose absorption mechanisms alone, sitagliptin operates through the incretin system—a natural bodily process that regulates blood glucose levels in response to food intake.\nThe 100 mg strength available in GLISITAPTIN 100 represents the standard therapeutic dose for most adult patients, providing optimal efficacy while maintaining an excellent safety margin. This once-daily formulation simplifies treatment regimens and promotes better adherence, which is crucial for long-term diabetes management success.\nHow GLISITAPTIN 100 Works\nGLISITAPTIN 100 works through a sophisticated yet elegant mechanism that harnesses your body's natural glucose regulation system. When you eat, your intestines release hormones called incretins, specifically GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). These incretins have multiple beneficial effects: they stimulate insulin secretion from the pancreas, suppress glucagon release (which reduces glucose production by the liver), and slow gastric emptying.\nHowever, these beneficial incretins are rapidly broken down by an enzyme called DPP-4, limiting their glucose-lowering effects. GLISITAPTIN 100 inhibits this DPP-4 enzyme, allowing incretins to remain active in your bloodstream for longer periods. This results in better insulin secretion when blood glucose is elevated, reduced glucagon levels, and ultimately improved blood sugar control throughout the day.\nImportantly, because this mechanism is glucose-dependent, GLISITAPTIN 100 primarily works when blood sugar is elevated, which significantly reduces the risk of hypoglycemia (dangerously low blood sugar) compared to some other diabetes medications.\nPrimary Uses and Indications\nType 2 Diabetes Mellitus Management: GLISITAPTIN 100 is primarily indicated for improving glycemic control in adult patients with type 2 diabetes mellitus. It can be prescribed as:\n\nMonotherapy: As a first-line treatment for patients who cannot achieve adequate control through diet and exercise alone, particularly when metformin is contraindicated or not tolerated\nCombination Therapy: Alongside metformin, sulfonylureas, thiazolidinediones, or insulin when these medications alone do not provide sufficient glucose control\nTriple Therapy: In combination with two other antidiabetic agents when dual therapy fails to achieve target HbA1c levels\n\nThe medication is particularly suitable for patients who require effective glucose control but have concerns about weight gain or hypoglycemia, as GLISITAPTIN 100 is weight-neutral and has a low hypoglycemia risk when used as monotherapy.\nKey Benefits of GLISITAPTIN 100\n1. Effective Glycemic Control\nClinical studies have demonstrated that GLISITAPTIN 100 significantly reduces HbA1c levels (a measure of long-term blood sugar control) by approximately 0.5-1.0%, helping patients achieve and maintain target glucose levels. This improvement translates to reduced risk of diabetes-related complications over time.\n2. Low Hypoglycemia Risk\nUnlike sulfonylureas or insulin, GLISITAPTIN 100 has a glucose-dependent mechanism, meaning it primarily works when blood sugar is elevated. This dramatically reduces the risk of hypoglycemic episodes, providing patients with greater safety and peace of mind, especially important for elderly patients or those with unpredictable meal schedules.\n3. Weight Neutral\nGLISITAPTIN 100 does not cause weight gain, a significant advantage over some other diabetes medications like insulin, sulfonylureas, or thiazolidinediones. Maintaining a healthy body weight is crucial for overall diabetes management and cardiovascular health.\n4. Once-Daily Convenience\nThe single daily dose requirement of GLISITAPTIN 100 simplifies treatment regimens, making it easier for patients to maintain adherence. Better adherence directly correlates with improved glycemic control and better long-term outcomes.\n5. Pancreatic Preservation\nBy working through the incretin system, GLISITAPTIN 100 may help preserve pancreatic beta-cell function, potentially slowing the progression of type 2 diabetes. This represents a significant long-term benefit beyond simple glucose control.\n6. Cardiovascular Safety\nClinical trials have demonstrated cardiovascular safety with sitagliptin, an important consideration given that cardiovascular disease is the leading cause of morbidity and mortality in patients with type 2 diabetes.\n7. Renal Dosing Available\nWhile the 100 mg dose is standard, sitagliptin can be adjusted for patients with kidney impairment, making it accessible to a broader patient population, including those with diabetic nephropathy.\n8. Well-Tolerated\nGLISITAPTIN 100 generally has a favorable side effect profile, with most patients experiencing minimal adverse effects, contributing to better quality of life during treatment.\nDosage and Administration\nThe standard recommended dose of GLISITAPTIN 100 is one tablet taken orally once daily, with or without food. The medication can be taken at any time of day, though taking it at the same time daily helps establish a routine and ensures consistent blood levels.\nFor patients with moderate to severe kidney disease, dosage adjustments may be necessary. Your healthcare provider will determine the appropriate dose based on your kidney function tests. It's crucial to follow your doctor's instructions precisely and not adjust your dose without medical guidance.\nPotential Side Effects\nWhile GLISITAPTIN 100 is generally well-tolerated, like all medications, it may cause side effects in some individuals:\nCommon Side Effects (Affecting 1-10% of patients):\n\nUpper respiratory tract infections\nNasopharyngitis (common cold symptoms)\nHeadache\nNausea\nAbdominal pain\nDiarrhea\n\nThese side effects are typically mild and often resolve on their own as your body adjusts to the medication.\nLess Common but Serious Side Effects:\n\nPancreatitis: Severe abdominal pain that may radiate to the back, with or without vomiting, requires immediate medical attention\nSevere Joint Pain: Persistent, severe joint pain has been reported in some patients; inform your doctor if this occurs\nAllergic Reactions: Rare cases of serious allergic reactions including anaphylaxis, angioedema, and severe skin reactions have occurred\nHeart Failure: In patients with existing heart disease, worsening heart failure has been reported\nBullous Pemphigoid: A rare skin condition requiring discontinuation of the medication\n\nWhen Used with Other Diabetes Medications:\nWhen GLISITAPTIN 100 is combined with sulfonylureas or insulin, the risk of hypoglycemia increases. Your doctor may reduce the dose of these medications when adding GLISITAPTIN 100 to your regimen.\nPrecautions and Contraindications\nDo Not Use GLISITAPTIN 100 if:\n\nYou are allergic to sitagliptin or any ingredients in the formulation\nYou have type 1 diabetes or diabetic ketoacidosis\nYou are under 18 years of age (safety and efficacy not established)\n\nUse with Caution if:\n\nYou have a history of pancreatitis\nYou have kidney disease (dose adjustment required)\nYou have heart failure\nYou are pregnant or planning to become pregnant\nYou are breastfeeding\n\nImportant Patient Information\nMonitoring: Regular monitoring of blood glucose levels and HbA1c testing (typically every 3-6 months) is essential to assess treatment effectiveness and make necessary adjustments.\nLifestyle Factors: GLISITAPTIN 100 works best when combined with a healthy diet, regular physical activity, and weight management. Medication alone cannot substitute for comprehensive lifestyle management.\nMissed Dose: If you miss a dose, take it as soon as you remember on the same day. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Never double up doses.\nStorage: Store GLISITAPTIN 100 at room temperature, away from moisture and heat. Keep the medication in its original container and out of reach of children.\nDrug Interactions\nGLISITAPTIN 100 has few significant drug interactions, contributing to its safety profile. However, inform your healthcare provider about all medications, supplements, and herbal products you're taking. Particular attention should be paid to:\n\nOther diabetes medications (may require dose adjustments)\nDigoxin (levels may be slightly increased)\nMedications affecting kidney function\n\nConclusion\nGLISITAPTIN 100 (Sitagliptin Phosphate 100 mg) represents a modern, effective, and well-tolerated option for managing type 2 diabetes mellitus. Its innovative mechanism through the incretin system offers multiple advantages including effective glucose control, low hypoglycemia risk, weight neutrality, and once-daily convenience. These benefits make it an excellent choice for many patients, whether used alone or in combination with other antidiabetic medications.", "price": 464.0, "discountamount": 139.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2272, "imageuri": "https://productimages.withfloats.com/actual/6961f2c8ba33389b8e9f0122.png", "tileimageuri": "https://productimages.withfloats.com/tile/6961f2c8ba33389b8e9f0122.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-10T06:33:41.727Z", "updatedon": "2026-03-13T05:59:37.431Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/sitagliptin-phosphate-100-mg/2272", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "GLISITAPTIN 100", "category": "DIABETIC RANGE", "tags": [ "sitagliptin phosphate 100 mg tablet uses", "sitagliptin phosphate 100 mg dosage", "sitagliptin phosphate 100 mg side effects", "sitagliptin phosphate 100 mg benefits", "sitagliptin phosphate 100 mg price in india", "sitagliptin phosphate tablets 100 mg", "what is sitagliptin phosphate 100 mg used for", "how sitagliptin phosphate works in diabetes", "sitagliptin phosphate 100 mg for type 2 diabetes", "sitagliptin phosphate 100 mg mechanism of action", "sitagliptin phosphate tablet how to take", "medicine to control blood sugar sitagliptin", "tablet for post meal blood sugar control", "sitagliptin phosphate for high blood sugar", "can sitagliptin phosphate cause weight gain" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "695b65af2800555f6696a6cf", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cinacalcet 60 mg Tablet", "description": "CINASELECT 60: Comprehensive Guide to Cinacalcet 60 mg Tablets\nProduct Overview\nCINASELECT 60 is a pharmaceutical formulation containing Cinacalcet hydrochloride 60 mg as its active ingredient. This medication represents a significant advancement in the management of calcium metabolism disorders, particularly in patients with chronic kidney disease and parathyroid conditions. As a calcimimetic agent, CINASELECT 60 works by mimicking the action of calcium on tissues, helping to restore hormonal balance and mineral homeostasis in the body.\nThe 60 mg dosage strength offers an effective therapeutic option for patients requiring moderate to higher-level intervention in managing parathyroid hormone levels and associated calcium imbalances. CINASELECT 60 is manufactured under strict quality control standards, ensuring consistency, purity, and efficacy in every tablet.\nUnderstanding How CINASELECT 60 Works\nCINASELECT 60 operates through a sophisticated mechanism that targets the calcium-sensing receptors located on the surface of parathyroid gland cells. These receptors play a crucial role in regulating parathyroid hormone secretion, which in turn controls calcium and phosphorus levels in the bloodstream.\nWhen you take CINASELECT 60, the active ingredient cinacalcet binds to these calcium-sensing receptors, increasing their sensitivity to extracellular calcium. This enhanced sensitivity tricks the parathyroid glands into “thinking” there is more calcium present in the blood than there actually is. As a result, the glands reduce their production and release of parathyroid hormone (PTH).\nBy lowering PTH levels, CINASELECT 60 subsequently reduces calcium levels in the blood and decreases the amount of phosphorus absorbed from the intestines. This cascade effect helps restore the delicate mineral balance that is often disrupted in patients with kidney disease or parathyroid disorders.\nPrimary Therapeutic Uses\nSecondary Hyperparathyroidism in Chronic Kidney Disease\nThe primary indication for CINASELECT 60 is the treatment of secondary hyperparathyroidism in adult patients with chronic kidney disease (CKD) who are on dialysis. When kidneys fail to function properly, they cannot adequately regulate calcium and phosphorus levels, leading to excessive parathyroid hormone production. This condition can result in serious complications including bone disease, cardiovascular calcification, and increased mortality risk.\nCINASELECT 60 helps manage this condition by controlling PTH levels, thereby reducing the risk of bone complications such as osteitis fibrosa cystica and preventing the dangerous deposition of calcium in blood vessels and soft tissues.\nHypercalcemia in Parathyroid Carcinoma\nCINASELECT 60 is also indicated for treating hypercalcemia (elevated blood calcium levels) in patients with parathyroid carcinoma, a rare malignant tumor of the parathyroid glands. In these cases, the medication helps control the dangerously high calcium levels that can lead to kidney stones, bone pain, digestive issues, and neurological symptoms.\nPrimary Hyperparathyroidism\nFor patients with severe hypercalcemia due to primary hyperparathyroidism who cannot undergo parathyroidectomy or for whom surgery has failed, CINASELECT 60 offers a valuable medical management option. This provides relief for patients who are not surgical candidates due to advanced age, comorbidities, or other contraindications.\nKey Benefits of CINASELECT 60\nEffective PTH Control\nClinical studies have demonstrated that CINASELECT 60 significantly reduces parathyroid hormone levels in a dose-dependent manner. This reduction helps prevent the cascade of complications associated with elevated PTH, including bone mineral loss and cardiovascular calcification.\nImproved Calcium-Phosphorus Balance\nBy reducing PTH secretion, CINASELECT 60 helps normalize serum calcium and phosphorus levels. This is particularly important in dialysis patients, where mineral imbalances can lead to serious complications affecting bone health, cardiovascular function, and overall quality of life.\nReduced Cardiovascular Risk\nElevated calcium and phosphorus levels contribute to vascular calcification, a major risk factor for cardiovascular disease in patients with chronic kidney disease. By managing these mineral levels, CINASELECT 60 may help reduce the risk of cardiovascular complications, which are the leading cause of death in dialysis patients.\nBone Health Preservation\nUncontrolled secondary hyperparathyroidism leads to renal osteodystrophy, a condition characterized by abnormal bone metabolism. CINASELECT 60 helps protect bone integrity by normalizing PTH levels, potentially reducing fracture risk and preserving bone mineral density.\nAlternative to Surgery\nFor patients with primary hyperparathyroidism or parathyroid carcinoma who cannot undergo surgery, CINASELECT 60 provides an effective medical management option. This is particularly valuable for elderly patients or those with multiple comorbidities that make surgery risky.\nQuality of Life Improvement\nBy controlling symptoms associated with hypercalcemia and hyperparathyroidism, such as bone pain, muscle weakness, fatigue, and digestive issues, CINASELECT 60 can significantly improve patients' overall quality of life and functional capacity.\nConvenient Oral Administration\nCINASELECT 60 is administered orally, making it more convenient than injectable alternatives. This allows for outpatient management and reduces the burden on healthcare facilities and patients.\nPotential Side Effects and Adverse Reactions\nCommon Side Effects\nPatients taking CINASELECT 60 may experience several common side effects, which typically include nausea and vomiting, occurring in approximately 20-30% of patients. These gastrointestinal symptoms are usually mild to moderate and may improve over time as the body adjusts to the medication.\nDiarrhea is another frequent complaint, affecting roughly 20% of users. Some patients also report muscle pain or myalgia, dizziness, loss of appetite, and asthenia (general weakness or fatigue).\nSerious Side Effects Requiring Medical Attention\nHypocalcemia: The most significant risk associated with CINASELECT 60 is the development of low calcium levels in the blood. Severe hypocalcemia can lead to paresthesias (tingling sensations), muscle cramps or spasms, tetany, seizures, and QT interval prolongation on electrocardiogram, which can predispose to dangerous heart rhythm abnormalities.\nGastrointestinal Bleeding: There have been reports of gastrointestinal hemorrhage in patients taking cinacalcet, particularly in those with risk factors such as gastritis, ulcers, or concurrent use of other medications that increase bleeding risk.\nAdynamic Bone Disease: Oversuppression of PTH can lead to adynamic bone disease, a condition where bone turnover becomes abnormally low, potentially weakening bones despite normalized calcium levels.\nCardiovascular Effects: Some patients may experience worsening heart failure or arrhythmias, particularly if hypocalcemia develops. Close monitoring is essential in patients with underlying cardiovascular disease.\nAllergic Reactions: Though rare, hypersensitivity reactions including rash, urticaria, and angioedema have been reported.\nPrecautions and Contraindications\nCINASELECT 60 should not be used in patients with serum calcium levels below the normal range. It requires careful dose adjustment and monitoring in patients with hepatic impairment. The medication may interact with drugs metabolized by the CYP2D6 enzyme system and with medications that affect gastric pH.\nPregnant or breastfeeding women should use CINASELECT 60 only if clearly needed, as its safety in these populations has not been fully established. Regular monitoring of serum calcium, phosphorus, and PTH levels is essential throughout treatment.\nDosage and Administration Guidelines\nCINASELECT 60 should be taken orally with food or shortly after a meal, as this improves absorption and reduces gastrointestinal side effects. Tablets should be swallowed whole and not crushed, chewed, or divided.\nThe typical starting dose for secondary hyperparathyroidism is lower than 60 mg, with gradual titration based on PTH and calcium levels. The 60 mg strength is often used as part of the dose escalation process or as a maintenance dose once optimal PTH control is achieved.\nDose adjustments should be made no more frequently than every two to four weeks, as it takes this long to see the full effect of a dose change on PTH levels. Treatment should be individualized based on laboratory values and clinical response.\nMonitoring Requirements\nPatients on CINASELECT 60 require regular monitoring of serum calcium, phosphorus, and intact PTH levels. Calcium levels should be checked within one week of starting treatment or after any dose adjustment, and then monthly once stable. PTH levels should be measured one to four weeks after initiation or dose adjustment, then every one to three months during maintenance therapy.\nAdditionally, patients should be monitored for signs and symptoms of hypocalcemia, particularly during the initial treatment period. Electrocardiogram monitoring may be appropriate in patients at risk for QT prolongation.\nStorage and Handling\nCINASELECT 60 should be stored at room temperature, away from moisture and direct sunlight. The medication should be kept in its original container with the lid tightly closed to protect from humidity. Keep out of reach of children and pets. Do not use past the expiration date printed on the package.\nConclusion\nCINASELECT 60 (Cinacalcet 60 mg) represents a valuable therapeutic option in the management of secondary hyperparathyroidism associated with chronic kidney disease, hypercalcemia in parathyroid carcinoma, and primary hyperparathyroidism in patients who cannot undergo surgery. Its unique mechanism as a calcimimetic agent provides effective control of parathyroid hormone secretion, helping to restore mineral balance and prevent serious complications.\nThe benefits of CINASELECT 60 extend beyond simple laboratory value normalization. By controlling PTH, calcium, and phosphorus levels, this medication helps preserve bone health, reduce cardiovascular calcification risk, and improve overall quality of life for patients dealing with complex metabolic disorders. For patients who are not surgical candidates, CINASELECT 60 offers hope and effective symptom management.\nHowever, like all medications, CINASELECT 60 must be used judiciously under close medical supervision. The risk of hypocalcemia and other potential side effects necessitates regular laboratory monitoring and open communication between patients and healthcare providers. Patients should report any concerning symptoms promptly and attend all scheduled follow-up appointments.", "price": 740.0, "discountamount": 222.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2266, "imageuri": "https://productimages.withfloats.com/actual/695b65ebf30763183f64d4f7.png", "tileimageuri": "https://productimages.withfloats.com/tile/695b65ebf30763183f64d4f7.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-05T07:18:07.264Z", "updatedon": "2026-05-01T06:30:26.075Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//cinacalcet-60-mg-tablet/2266", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CINASELECT 60", "category": "NEPHROLOGYRANGE", "tags": [ "cinacalcet 60 mg", "cinacalcet mechanism of action.", "cinacalcet uses", "tab cinacalcet.", "cinacalcet dose.", "cinacalcet structure.", "cinacalcet tab.", "calcium and phosphorus levels in the bloodstream.", "parathyroid hormone secretion.", "calcium metabolism disorders.", "chronic kidney disease and parathyroid conditions.", "cinacalcet 60 mg", "cinacalcet 60", "Cinacalcet Tablets 60 mg price in India", "Buy Cinacalcet Tablets 60 mg online", "Cinacalcet 60 mg wholesale price", "Buy Cinacalcet Tablets 60 mg", "Get Cinacalcet Tablets 60 mg at best price" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "694cf85408591c1173b54c2f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Pregabalin Epalrestat and Methylcobalamin Tablets", "description": "EPSTATE ED represents an advanced pharmaceutical formulation that combines three powerful therapeutic agents: Pregabalin, Epalrestat, and Methylcobalamin. This innovative triple-combination medication is specifically designed to address the complex pathophysiology of diabetic neuropathy and neuropathic pain conditions. By integrating multiple mechanisms of action, EPSTATE ED offers a comprehensive approach to managing nerve-related complications that significantly impact the quality of life for millions of individuals worldwide.\nThe formulation addresses not only the symptomatic relief of neuropathic pain but also targets the underlying metabolic derangements that contribute to nerve damage progression. This multi-pronged therapeutic strategy makes EPSTATE ED particularly valuable for patients who require more than symptomatic management alone.\nUnderstanding the Active Components\nPregabalin: The Neuropathic Pain Modulator\nPregabalin serves as the cornerstone analgesic component in EPSTATE ED. This anticonvulsant medication works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. Through this mechanism, Pregabalin reduces the release of excitatory neurotransmitters including glutamate, norepinephrine, and substance P. This reduction in neurotransmitter release effectively dampens the abnormal neural signaling that characterizes neuropathic pain conditions.\nThe molecule demonstrates excellent bioavailability and rapid absorption, allowing patients to experience relief within a relatively short timeframe. Its efficacy in managing various neuropathic pain syndromes has been extensively documented in clinical trials, establishing it as a first-line agent for diabetic peripheral neuropathy, postherpetic neuralgia, and other chronic neuropathic pain conditions.\nEpalrestat: The Aldose Reductase Inhibitor\nEpalrestat represents a unique addition to the formulation, functioning as a selective aldose reductase inhibitor. In diabetic conditions, excess glucose is converted to sorbitol through the polyol pathway, with aldose reductase serving as the rate-limiting enzyme. The accumulation of sorbitol within nerve cells leads to osmotic stress, depletion of myoinositol, and subsequent nerve dysfunction.\nBy inhibiting aldose reductase, Epalrestat prevents this harmful sorbitol accumulation, thereby addressing one of the fundamental metabolic abnormalities responsible for diabetic neuropathy. This disease-modifying approach distinguishes EPSTATE ED from purely symptomatic treatments. Epalrestat has been particularly well-studied in Asian populations and has demonstrated the ability to improve nerve conduction velocities and reduce subjective neuropathic symptoms over time.\nMethylcobalamin: The Neurotropic Vitamin\nMethylcobalamin, the bioactive form of Vitamin B12, completes the therapeutic triad in EPSTATE ED. Unlike cyanocobalamin, which requires conversion in the body, methylcobalamin is immediately available for utilization in crucial biochemical processes. It plays an indispensable role in myelin synthesis, the protective sheath surrounding nerve fibers that enables proper signal transmission.\nThis coenzyme participates in methionine synthesis and is essential for maintaining the structural and functional integrity of neurons. Methylcobalamin also facilitates nerve regeneration and has demonstrated neuroprotective properties in various experimental models. For patients with diabetic neuropathy, who often exhibit Vitamin B12 deficiency (sometimes exacerbated by metformin therapy), supplementation with methylcobalamin addresses both nutritional deficits and supports nerve health at a fundamental level.\nClinical Applications and Uses\nEPSTATE ED is primarily indicated for the comprehensive management of diabetic peripheral neuropathy, a condition affecting approximately 50% of individuals with long-standing diabetes. The symptoms of this condition range from tingling sensations and burning pain to numbness and loss of protective sensation, which can lead to serious complications including foot ulcers and amputations.\nBeyond diabetic neuropathy, EPSTATE ED may be prescribed for various neuropathic pain syndromes where the combination of pain relief, metabolic correction, and nerve support proves beneficial. Patients experiencing chronic nerve pain resulting from metabolic disturbances, nutritional deficiencies, or structural nerve damage may find this combination particularly effective.\nThe medication is typically recommended for adults who have not achieved adequate symptom control with single-agent therapy or who would benefit from the synergistic effects of the three components. Healthcare providers may prescribe EPSTATE ED when a patient requires both immediate symptom relief and long-term disease modification.\nKey Benefits and Therapeutic Advantages\nComprehensive Multi-Mechanism Action\nThe primary advantage of EPSTATE ED lies in its multi-faceted approach to neuropathic conditions. Rather than addressing only pain symptoms, the formulation simultaneously tackles pain perception, underlying metabolic abnormalities, and nutritional support for nerve health. This comprehensive strategy may lead to superior outcomes compared to monotherapy approaches.\nEnhanced Pain Relief\nClinical evidence supporting Pregabalin's efficacy in neuropathic pain is substantial. Patients often report significant reductions in pain intensity, improved sleep quality due to decreased nocturnal pain, and enhanced ability to perform daily activities. The pain-relieving effects typically manifest within the first week of therapy and continue to improve with ongoing treatment.\nDisease Modification Potential\nUnlike purely symptomatic treatments, the inclusion of Epalrestat provides genuine disease-modifying potential. By targeting the polyol pathway, EPSTATE ED may slow the progression of nerve damage in diabetic patients. Long-term use may preserve nerve function and prevent the worsening of neuropathic symptoms, offering hope beyond mere symptom management.\nImproved Nerve Conduction and Function\nThe combination of metabolic correction through Epalrestat and neurotropic support via Methylcobalamin creates an environment conducive to nerve regeneration and functional improvement. Studies have demonstrated improvements in nerve conduction velocity parameters with similar combination therapies, suggesting potential restoration of nerve function rather than simple symptom masking.\nConvenience of Combination Therapy\nFor patients who would otherwise require multiple separate medications, EPSTATE ED offers the convenience of a single tablet containing all three therapeutic agents. This simplification of medication regimens improves compliance, reduces pill burden, and may enhance overall treatment outcomes.\nQuality of Life Enhancement\nThe cumulative effect of pain reduction, improved nerve function, and better metabolic control translates into meaningful quality of life improvements. Patients report better mobility, reduced interference of pain with daily activities, improved mood, and enhanced social functioning.\nPotential Side Effects and Safety Considerations\nCommon Side Effects\nAs with any pharmaceutical agent, EPSTATE ED may produce certain adverse effects. The most commonly reported side effects are primarily attributable to the Pregabalin component and include dizziness, somnolence, peripheral edema, dry mouth, blurred vision, weight gain, and difficulty with concentration or attention. These effects are generally mild to moderate and often diminish with continued therapy as the body adapts to the medication.\nGastrointestinal symptoms such as constipation or nausea may occur, though they are typically manageable with dietary modifications or symptomatic treatment. Some patients experience increased appetite leading to weight gain, which requires monitoring, particularly in diabetic individuals where weight management is crucial.\nSerious but Rare Adverse Events\nThough uncommon, certain serious adverse effects warrant immediate medical attention. These include allergic reactions manifesting as rash, itching, swelling, severe dizziness, or breathing difficulties. Pregabalin has been associated with rare cases of angioedema, which requires prompt discontinuation and medical intervention.\nMental health changes, including mood alterations, anxiety, depression, agitation, or suicidal thoughts, have been reported with Pregabalin use, particularly in individuals with pre-existing psychiatric conditions. Patients and caregivers should remain vigilant for behavioral changes and report them immediately to healthcare providers.\nDrug Interactions and Precautions\nEPSTATE ED may interact with other central nervous system depressants, including alcohol, opioids, benzodiazepines, and antihistamines, potentially intensifying sedation and cognitive impairment. Patients should inform their healthcare provider of all medications, supplements, and substances they consume.\nIndividuals with kidney impairment require dose adjustments since Pregabalin is primarily eliminated through renal excretion. Regular monitoring of renal function may be necessary during long-term therapy.\nSpecial Population Considerations\nPregnant or breastfeeding women should use EPSTATE ED only when clearly necessary and under strict medical supervision, as the safety profile in these populations has not been fully established. Elderly patients may be more susceptible to side effects, particularly dizziness and confusion, necessitating careful dose titration and monitoring.\nPatients should be advised against abrupt discontinuation of EPSTATE ED, as sudden cessation of Pregabalin may precipitate withdrawal symptoms including insomnia, nausea, headache, anxiety, and sweating. Gradual dose reduction under medical supervision is recommended when discontinuing therapy.\nDosage and Administration Guidelines\nThe appropriate dosage of EPSTATE ED is highly individualized and should be determined by a qualified healthcare professional based on the patient's specific condition, response to therapy, and tolerance. Typically, treatment begins with a lower dose that is gradually increased to achieve optimal therapeutic benefit while minimizing adverse effects.\nPatients should take EPSTATE ED exactly as prescribed, with or without food, at consistent times each day to maintain stable blood levels. Missing doses should be addressed by taking the forgotten dose as soon as remembered, unless it's nearly time for the next scheduled dose. Double dosing to compensate for missed doses is not recommended.\nRegular follow-up appointments allow healthcare providers to assess treatment efficacy, monitor for adverse effects, and make necessary dose adjustments. Patients should maintain open communication with their medical team regarding symptom improvement, side effects, and any concerns that arise during therapy.\nPatient Counseling and Lifestyle Recommendations\nMaximizing the benefits of EPSTATE ED extends beyond simply taking the medication. Patients should be counseled on complementary lifestyle measures that support neuropathy management. Maintaining optimal glycemic control remains paramount for diabetic patients, as blood sugar management directly impacts neuropathy progression regardless of medication.\nRegular physical activity, within individual capabilities, promotes circulation, supports nerve health, and may enhance the therapeutic effects of EPSTATE ED. Daily foot examinations become critical for diabetic patients to identify potential injuries early, preventing serious complications.\nNutritional optimization, including adequate intake of B vitamins, antioxidants, and essential nutrients, supports the neurotropic effects of Methylcobalamin. Avoiding alcohol and tobacco, both of which can exacerbate neuropathy, is strongly recommended.\nPatients should be cautioned about activities requiring alertness, such as driving or operating machinery, especially during the initial treatment phase when dizziness and somnolence may be more pronounced. These effects typically improve with continued therapy, but individual responses vary.\nConclusion\nEPSTATE ED represents a thoughtfully designed pharmaceutical formulation that addresses the multifaceted nature of diabetic neuropathy and neuropathic pain through its unique combination of Pregabalin, Epalrestat, and Methylcobalamin. This triple-action approach offers patients more than symptomatic relief—it provides genuine disease modification potential, nutritional support, and comprehensive nerve health optimization.\nThe synergistic effects of these three components create a therapeutic profile that is greater than the sum of its parts. While Pregabalin efficiently manages pain symptoms and improves quality of life in the short term, Epalrestat works to address underlying metabolic derangements that drive disease progression, and Methylcobalamin provides essential neurotropic support for nerve regeneration and function.\nFor patients struggling with the debilitating effects of neuropathic pain and diabetic neuropathy, EPSTATE ED offers renewed hope for better symptom control and potentially slowed disease progression. The convenience of combination therapy in a single tablet improves adherence and simplifies complex treatment regimens.\nHowever, EPSTATE ED is not without considerations. Potential side effects, though generally manageable, require awareness and monitoring. The medication is most effective when integrated into a comprehensive management plan that includes optimal glycemic control, lifestyle modifications, and regular medical supervision.\nUltimately, EPSTATE ED should be viewed as a valuable tool in the therapeutic arsenal against neuropathic conditions, best utilized under the guidance of knowledgeable healthcare professionals who can individualize treatment to each patient's unique needs and circumstances. With proper use, monitoring, and patient education, EPSTATE ED can significantly improve outcomes and quality of life for those affected by these challenging neurological conditions.", "price": 275.0, "discountamount": 82.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2253, "imageuri": "https://productimages.withfloats.com/actual/694cf859d25fa0b0657b1ac8.png", "tileimageuri": "https://productimages.withfloats.com/tile/694cf859d25fa0b0657b1ac8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-25T08:39:48.947Z", "updatedon": "2026-04-18T09:21:49.885Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//pregabalin-epalrestat-and-methylcobalamin-tablets/2253", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "EPSTATE ED", "category": "NEUROLOGYRANGE", "tags": [ "regabalin, Epalrestat, and Methylcobalamin.neuropathic pain conditions.", "Pregabalin, Epalrestat, and Methylcobalamin.", "neuropathic pain.", "diabetic neuropathy.", "sorbitol within nerve cells leads to osmotic stress.", "Epalrestat and neurotropic support via Methylcobalamin creates an environment .", "mood alterations, anxiety, depression, agitation.", "supports the neurotropic effects of Methylcobalamin.", "Pregabalin Epalrestat and Methylcobalamin Tablets", "epalrestat and methylcobalamin tablets uses", "epalrestat and methylcobalamin tablets in hindi", "pregabalin epalrestat and methylcobalamin tablets price jaipur", "pregabalin epalrestat and methylcobalamin tablets price india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "68b6d6c76f14ecfa6add5d56", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Sacubitril and Valsartan Tablets 97 mg + 103 mg", "description": "Description: \nSACUSMART 200 is a combination medicine containing Sacubitril (97 mg) and Valsartan (103 mg), specifically designed to manage chronic heart failure with reduced ejection fraction (HFrEF). This dual-acting therapy is classified as an angiotensin receptor neprilysin inhibitor (ARNI) and is widely prescribed to reduce the risk of cardiovascular death and hospitalization in patients with heart failure.\n\nHeart failure is a progressive condition where the heart cannot pump blood efficiently to meet the body’s needs. SACUSMART 200 improves the efficiency of the heart by relaxing blood vessels, reducing fluid retention, and lowering strain on the heart, helping patients live a better and longer life.\n\nWhat is SACUSMART 200?\nSACUSMART 200 is a highly effective heart failure medication that combines two active components:\nSacubitril (97 mg) – a neprilysin inhibitor that increases levels of natriuretic peptides, leading to vasodilation, sodium excretion, and reduced stress on the heart.\n\nValsartan (103 mg) – an angiotensin II receptor blocker (ARB) that relaxes blood vessels, lowers blood pressure, and prevents harmful effects of angiotensin II.\nTogether, these mechanisms make SACUSMART 200 a superior alternative to traditional ACE inhibitors or ARBs alone in treating chronic heart failure.\nUses of SACUSMART 200\nSACUSMART 200 is prescribed for:\nChronic heart failure with reduced ejection fraction (HFrEF)\nReducing risk of hospitalization due to worsening heart failure\nImproving survival rates in patients with heart failure\nEnhancing exercise tolerance and quality of life in long-term heart failure management\nBenefits of SACUSMART 200\nDual action with neprilysin inhibition + ARB effect for comprehensive heart protection\nProven to reduce mortality and hospitalization risk in heart failure patients\n\nImproves symptoms such as breathlessness, fatigue, and swelling\nHelps patients regain better physical stamina and daily activity levels\nLong-term use significantly contributes to improved quality of life\nPossible Side Effects of SACUSMART 200.\nWhile SACUSMART 200 is effective and generally well tolerated, some patients may experience:\nLow blood pressure (hypotension)\nIncreased blood potassium levels (hyperkalemia)\nDizziness or light-headedness\nKidney function changes\nCough\nRarely, serious allergic reactions or angioedema (swelling of face, lips, or throat)\nImmediate medical attention is required if severe swelling, difficulty breathing, or fainting occurs.\nPrecautions Before Using SACUSMART 200.\nDo not use if you are allergic to sacubitril, valsartan, or other ARBs\nAvoid if you have taken an ACE inhibitor within the last 36 hours due to the risk of angioedema\nNot recommended for patients with a history of hereditary angioedema\nCaution in patients with severe kidney or liver disease\nPregnant and breastfeeding women should avoid this medicine due to harmful effects on the baby\nAlways monitor blood pressure, kidney function, and potassium levels while on this treatment\nDrug Interactions.\nSACUSMART 200 may interact with:\n\nACE inhibitors – should not be combined, risk of angioedema\n\nPotassium supplements or potassium-sparing diuretics – risk of high potassium\n\nNSAIDs (e.g., ibuprofen, naproxen) – may reduce kidney function\n\nLithium – risk of lithium toxicity\n\nDiuretics – may increase the risk of low blood pressure\n\nAlways inform your doctor about all medicines, supplements, or herbal products you are taking before starting SACUSMART 200.\n\n \nConclusion\n \n\nSACUSMART 200 (Sacubitril 97 mg & Valsartan 103 mg) is a breakthrough treatment in managing chronic heart failure with reduced ejection fraction (HFrEF). By combining neprilysin inhibition and angiotensin receptor blockade, it not only reduces symptoms but also significantly lowers the risk of hospitalization and death, improving both longevity and quality of life.\n\nFor patients living with heart failure, SACUSMART 200 offers a scientifically proven and clinically superior solution to regain control over their health and live a more fulfilling life.", "price": 750.0, "discountamount": 225.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2170, "imageuri": "https://productimages.withfloats.com/actual/68b6d6c9c4087f14f55d7d23.png", "tileimageuri": "https://productimages.withfloats.com/tile/68b6d6c9c4087f14f55d7d23.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-09-02T11:36:39.17Z", "updatedon": "2026-05-25T06:41:35.287Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//sacubitril-and-valsartan-tablets-97-mg-103-mg/2170", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "SACUSMART 200", "category": "CARDIOLOGYRANGE", "tags": [ "Sacubitril 97 mg and Valsartan 103 mg", "sacubitril and valsartan tablets uses", "sacubitril and valsartan tablets benefits", "sacubitril valsartan tablet dosage", "sacubitril and valsartan tablet mechanism of action", "sacubitril valsartan tablets side effects", "sacubitril valsartan tablet how it works", "sacubitril and valsartan tablets price in India", "sacubitril valsartan tablets manufacturer in India", "sacubitril and valsartan tablets brand name", "best sacubitril and valsartan tablets in India", "sacubitril valsartan tablets wholesale supplier", "what is sacubitril and valsartan tablet used for", "who should take sacubitril valsartan tablets", "sacubitril and valsartan tablets", "sacubitril and valsartan tablets 50 mg", "sacubitril and valsartan tablets uses in hindi", "uses of sacubitril and valsartan tablets", "sacubitril and valsartan tablets in hindi", "rx sacubitril and valsartan tablets", "sacubitril and valsartan tablets 100mg", "sacubitril and valsartan tablets in india", "sacubitril and valsartan tablets 100mg", "sacubitril and valsartan tablets in india", "use of sacubitril and valsartan tablets" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "66694f6bca84cd189c25ac3e", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Pirfenidone 400mg", "description": "PIRFENOID 400 is a pharmaceutical formulation containing Pirfenidone 400mg as its active ingredient. This medication represents a significant advancement in the treatment of idiopathic pulmonary fibrosis (IPF), a progressive lung disease characterized by scarring of lung tissue. PIRFENOID 400 belongs to a class of medications known as antifibrotic agents, designed to slow the progression of lung fibrosis and help patients maintain their quality of life.\nIdiopathic pulmonary fibrosis is a chronic, progressive condition where the lung tissue becomes thick and stiff over time, making it increasingly difficult for patients to breathe. PIRFENOID 400 works at the cellular level to address this scarring process, offering hope to those diagnosed with this challenging condition.\nUnderstanding How PIRFENOID 400 Works\nThe active ingredient in PIRFENOID 400, Pirfenidone, operates through multiple mechanisms to combat pulmonary fibrosis. While the exact mechanism is not completely understood, research suggests that Pirfenidone exhibits both antifibrotic and anti-inflammatory properties. It works by reducing the production of growth factors and procollagens, which are substances involved in the formation of scar tissue in the lungs.\nBy interfering with the fibrotic process, PIRFENOID 400 helps slow down the rate at which lung tissue becomes scarred and damaged. This intervention is crucial because once lung tissue becomes severely scarred, the damage is generally irreversible. The medication doesn't cure IPF, but it can significantly slow its progression, allowing patients to maintain better lung function for longer periods.\nPrimary Uses and Indications\nPIRFENOID 400 is primarily prescribed for the treatment of mild to moderate idiopathic pulmonary fibrosis. Healthcare providers recommend this medication for patients who have been diagnosed with IPF through comprehensive testing, including high-resolution CT scans, pulmonary function tests, and sometimes lung biopsies.\nThe medication is most effective when started early in the disease process, before extensive lung damage has occurred. It is intended for long-term use as part of a comprehensive treatment plan that may also include pulmonary rehabilitation, oxygen therapy, and other supportive measures.\nKey Benefits of PIRFENOID 400\nSlowing Disease Progression\nThe most significant benefit of PIRFENOID 400 is its ability to slow the progression of idiopathic pulmonary fibrosis. Clinical studies have demonstrated that patients taking Pirfenidone experience a reduced decline in lung function compared to those not receiving treatment. This means patients can maintain their breathing capacity and overall lung health for extended periods.\nImproved Quality of Life\nBy slowing disease progression, PIRFENOID 400 helps patients maintain their ability to perform daily activities. Patients often report being able to continue working, engaging in social activities, and maintaining independence longer than they might without treatment. This preservation of quality of life is invaluable for both patients and their families.\nReduced Risk of Acute Exacerbations\nResearch indicates that PIRFENOID 400 may help reduce the risk of acute exacerbations of IPF, which are sudden worsening episodes that can be life-threatening. By stabilizing the disease, the medication provides patients with more predictable disease management and fewer emergency situations.\nExtended Survival Rates\nStudies have shown that treatment with Pirfenidone may be associated with improved survival rates in IPF patients. While IPF remains a serious condition, PIRFENOID 400 offers patients additional time and better overall outcomes.\nWell-Established Safety Profile\nPIRFENOID 400 has been extensively studied in clinical trials involving thousands of patients worldwide. This extensive research has established a well-understood safety profile, allowing healthcare providers to effectively manage and monitor patients on this therapy.\nDosage and Administration\nPIRFENOID 400 is typically administered orally with food to reduce the likelihood of gastrointestinal side effects. The usual recommended dosage involves a gradual titration period where the dose is slowly increased over the initial weeks of treatment to help the body adjust to the medication. Patients should always follow their healthcare provider's specific dosing instructions and never adjust their dose without medical guidance.\nPotential Side Effects\nLike all medications, PIRFENOID 400 can cause side effects, though not everyone experiences them. Understanding these potential effects helps patients and healthcare providers monitor treatment effectively.\nCommon Side Effects\nThe most frequently reported side effects include nausea, loss of appetite, stomach upset, diarrhea, and indigestion. These gastrointestinal effects are often most noticeable when starting treatment but may improve over time. Taking the medication with food can help minimize these symptoms.\nSkin-related side effects are also common, including photosensitivity (increased sensitivity to sunlight), rash, and dry skin. Patients taking PIRFENOID 400 should use broad-spectrum sunscreen and protective clothing when exposed to sunlight.\nFatigue and dizziness are reported by some patients, particularly during the initial treatment period. These effects may impact daily activities and should be discussed with a healthcare provider if they persist or worsen.\nLess Common but Serious Side Effects\nElevated liver enzymes have been observed in some patients taking Pirfenidone, which is why regular liver function monitoring is essential during treatment. Most cases are mild and reversible with dose adjustment or temporary discontinuation.\nSome patients may experience significant weight loss, which requires nutritional monitoring and support. Rare cases of angioedema (severe swelling) and severe allergic reactions have been reported and require immediate medical attention.\nManaging Side Effects\nMost side effects can be effectively managed through dose adjustments, symptomatic treatment, or temporary interruption of therapy. Open communication with healthcare providers is essential for optimizing treatment while minimizing adverse effects.\nImportant Precautions and Monitoring\nPatients taking PIRFENOID 400 require regular monitoring, including liver function tests, typically performed monthly for the first six months and then periodically thereafter. Sun protection measures are crucial, including use of SPF 50+ sunscreen, protective clothing, and avoiding peak sun hours.\nWomen of childbearing potential should use effective contraception, as the safety of Pirfenidone during pregnancy has not been established. Patients should inform their healthcare provider of all other medications they are taking, as drug interactions may occur.\nSmoking can reduce the effectiveness of PIRFENOID 400, and patients are strongly encouraged to quit smoking as part of their comprehensive IPF management strategy.\nConclusion\nPIRFENOID 400 represents a valuable therapeutic option for patients diagnosed with idiopathic pulmonary fibrosis. By slowing disease progression, reducing the decline in lung function, and potentially improving survival outcomes, this medication offers meaningful benefits to those facing this challenging condition. While side effects can occur, they are generally manageable with appropriate monitoring and medical support.\n\n\n\n\n\n\n\n", "price": 439.0, "discountamount": 132.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "IPF", "rash", "drug", "400mg", "ORDER", "Email", "801mg", "nausea", "doctor", "fatigue", "product", "guidance", "WhatsApp", "PIRFENOID", "medication", "Pirfenidone", "information", "sterispharma", "inflammation", "Side effects", "usual dosage", "sterisonline", "lung scarring", "optimal results", "disease progression", "idiopathic pulmonary fibrosis" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1774, "imageuri": "https://productimages.withfloats.com/actual/66694f6d5e294343790b2279.png", "tileimageuri": "https://productimages.withfloats.com/tile/66694f6d5e294343790b2279.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-12T07:34:03.278Z", "updatedon": "2026-05-20T07:10:29.655Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//pirfenidone-400mg/1774", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "PIRFENOID 400", "category": "RESPIRTORYRANGE", "tags": [ "Pirfenidone (400mg) price", "pirfenidone 400 mg uses in hindi", "pirfenidone 400 mg side effects in hindi", "pirfenidone (400mg) benefits", "pirfenidone 400 mg tablet", "pirfenidone 400 mg tablets", "pirfenidone 400 mg price", "pirfenidone 400 mg dosage", "pirfenidone 400 mg composition", "buy pirfenidone 400 mg tablet", "pirfenidone 400 mg tablet manufacturer", "pirfenidone 400 mg tablet supplier", "pirfenidone 400 mg tablet wholesale", "pirfenidone 400 mg for pulmonary fibrosis", "pirfenidone 400 mg treatment benefits", "pirfenidone 400 mg tablets in India", "pirfenidone 400 mg supplier India", "Buy Pirfenidone 400mg online", "Order Pirfenidone 400mg online India", "Pirfenidone 400mg wholesale price" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "66680f6300e7d2232cab32fa", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "DANOZOLIS 50", "description": "DANOZOLIS 50\nDanazol (50mg)\nDanozolis 50 contains 50mg of Danazol, a synthetic steroid derivative with anti-estrogenic properties. It is primarily used in the treatment of endometriosis, fibrocystic breast disease, and hereditary angioedema. Danazol works by inhibiting the secretion of pituitary gonadotropins, thereby suppressing ovarian function and reducing estrogen levels.\n\nKey Features:\n\nMedication Class: Synthetic steroid derivative\nIndications: Endometriosis, fibrocystic breast disease, hereditary angioedema\nMechanism of Action: Inhibits pituitary gonadotropins, suppresses ovarian function, reduces estrogen levels\nDosage: Typically administered as 50mg capsules\nAdministration: Usually taken orally with or without food\nSide Effects: Possible side effects include weight gain, acne, oily skin, voice changes, and menstrual irregularities.\nPrecautions: Not recommended during pregnancy, lactation, or in patients with liver disease or certain hormone-related disorders. For further information:\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nOrder Now: \nhttps://www.sterisonline.com/product/danozolis-50-133830", "price": 129.0, "discountamount": 39.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "Call", "acne", "food", "Email", "Action", "Danazol", "WhatsApp", "patients", "treatment", "secretion", "oily skin", "DANOZOLIS", "lactation", "pregnancy", "weight gain", "information", "Precautions", "sterispharma", "sterisonline", "Key Features", "endometriosis", "voice changes", "liver disease", "Medication Class", "ovarian function", "Possible side effects", "estrogen levels Dosage", "pituitary gonadotropins", "menstrual irregularities", "hormone-related disorders", "anti-estrogenic properties", "fibrocystic breast disease", "50mg capsules Administration", "hereditary angioedema Mechanism", "Synthetic steroid derivative Indications" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1727, "imageuri": "https://productimages.withfloats.com/actual/667d2fc9c134db5b38ba7565.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/667d2fc9c134db5b38ba7565.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-11T08:48:35.916Z", "updatedon": "2026-03-26T06:22:18.396Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//danozolis-50/1727", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "DANOZOLIS 50", "category": "GYANECOLOGYRANGE", "tags": [ "DANOZOLIS 50", "Danazol 50mg tablet", "Danazol 50mg", "danazol 50 mg uses in hindi", "danazol कैप्सूल 100mg आईपी" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "66680e1254b2801048925e31", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "DANOZOLIS 200 ", "description": "DANOZOLIS 200 \nDanazol (200mg)\nDANOZOLIS 200 contains Danazol at a strength of 200mg. Danazol is a synthetic steroid that regulates hormone levels in the body. It is primarily used to treat conditions such as endometriosis, fibrocystic breast disease, and hereditary angioedema. Danazol works by suppressing the production of certain hormones, including estrogen and progesterone, which are involved in the development of these conditions. It is available in capsule form and should be taken as directed by a healthcare provider. Common side effects may include weight gain, acne, oily skin, and changes in menstrual flow.For further information:\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nOrder Now: \nhttps://www.sterisonline.com/product/danozolis-200-133829", "price": 426.0, "discountamount": 128.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "acne", "Call", "body", "Order", "Email", "200mg", "changes", "Danazol", "strength", "estrogen", "WhatsApp", "hormones", "DANOZOLIS", "oily skin", "production", "conditions", "weight gain", "information", "development", "sterispharma", "sterisonline", "capsule form", "progesterone", "endometriosis", "menstrual flow", "hormone levels", "synthetic steroid", "healthcare provider", "Common side effects", "hereditary angioedema", "fibrocystic breast disease" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1726, "imageuri": "https://productimages.withfloats.com/actual/667d2ff95e58b0758f7055eb.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/667d2ff95e58b0758f7055eb.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-11T08:42:58.074Z", "updatedon": "2026-03-26T06:23:36.264Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//danozolis-200-/1726", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "DANOZOLIS 200 ", "category": "GYANECOLOGYRANGE", "tags": [ "DANOZOLIS 200 mg", "Danazol 200mg price", "danozolis 200 uses", "danazol uses in gynecology", "danazol mechanism of action" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "66680b6733ebd40c046caee9", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Danazol 100 mg", "description": "DANOZOLIS 100 \nDanazol (100mg)\nDanozolis 100 contains Danazol, an androgen derivative used to treat conditions like endometriosis, fibrocystic breast disease, and hereditary angioedema. It works by affecting the ovaries and inhibiting ovulation. This medication is typically prescribed in a dose of 100mg, taken orally, with or without food, usually two to three times a day. Common side effects may include weight gain, acne, oily skin, menstrual changes, and headache. It's important to follow your doctor's instructions and report any unusual symptoms promptly. For further information:\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nOrder Now: \n\n\n\n\n\n\n\n", "price": 177.0, "discountamount": 53.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "Call", "acne", "food", "dose", "Email", "100mg", "Order", "doctor", "Danazol", "ovaries", "WhatsApp", "headache", "oily skin", "DANOZOLIS", "ovulation", "conditions", "medication", "information", "weight gain", "sterispharma", "instructions", "sterisonline", "endometriosis", "unusual symptoms", "menstrual changes", "androgen derivative", "Common side effects", "hereditary angioedema", "fibrocystic breast disease" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1725, "imageuri": "https://productimages.withfloats.com/actual/667d3023ce74849f89cdfe39.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/667d3023ce74849f89cdfe39.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-11T08:31:35.081Z", "updatedon": "2026-03-26T06:25:58.912Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//danazol-100-mg/1725", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "DANOZOLIS 100 ", "category": "GYANECOLOGYRANGE", "tags": [ "DANOZOLIS 100 mg", "Danazol 100mg price", "danazol mechanism of action", "danazol uses in gynecology", "danazol side effects female" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "665ee8be7b387b17ecbcbde3", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": " SACUBRIGHT 200 ", "description": "SACUBRIGHT 200 \nSacubitril (97mg), Valsartan (103mg)\nSACUBRIGHT 200 is a combination medication containing two active ingredients: Sacubitril (97mg) and Valsartan (103mg). This combination is designed to provide dual inhibition of the renin-angiotensin-aldosterone system (RAAS) for the treatment of heart failure with reduced ejection fraction (HFrEF).\n\nSacubitril is a neprilysin inhibitor, while Valsartan is an angiotensin II receptor blocker (ARB). Together, they work synergistically to improve cardiovascular outcomes in patients with HFrEF by targeting different pathways involved in the pathophysiology of heart failure.\n\nNeprilysin is an enzyme responsible for the degradation of natriuretic peptides, which play a crucial role in regulating blood pressure and fluid balance. By inhibiting neprilysin, Sacubitril increases the levels of natriuretic peptides, leading to vasodilation, natriuresis, and diuresis, which helps reduce blood pressure, preload, and afterload on the heart.\n\nValsartan, as an ARB, blocks the effects of angiotensin II, a vasoconstrictor and stimulator of aldosterone secretion. By antagonizing the angiotensin II type 1 (AT1) receptors, Valsartan dilates blood vessels, reduces blood pressure, and attenuates the deleterious effects of angiotensin II on cardiac remodeling and fibrosis.\n\nSACUBRIGHT 200 is indicated for the treatment of symptomatic HFrEF in patients with New York Heart Association (NYHA) class II-IV heart failure. Clinical studies have demonstrated that this combination therapy reduces the risk of cardiovascular death and hospitalization for heart failure compared to traditional therapy with angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) alone.\n\nAs with any medication, SACUBRIGHT 200 may cause side effects, including hypotension, hyperkalemia, renal impairment, and angioedema. Patients should be monitored regularly for these adverse effects, especially during initiation and dose titration.\n\nOverall, SACUBRIGHT 200 represents an innovative approach to the management of HFrEF, offering superior efficacy and cardiovascular benefits compared to standard therapy. However, it should only be used under the supervision of a healthcare professional experienced in the management of heart failure and in accordance with established treatment guidelines.\n\nFor further information: \nEMAIL: info@sterispharma.com / contact@sterispharma.com \n CALL/WHATSAPP: 7877551268, 7849827488 \n Order Now\nhttps://www.sterisonline.com/product/sacubright-200-134307\n\n\n\n", "price": 740.0, "discountamount": 222.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "ARB", "risk", "RAAS", "EMAIL", "Order", "levels", "diuresis", "fibrosis", "patients", "Valsartan", "stimulator", "initiation", "angioedema", "SACUBRIGHT", "accordance", "management", "Sacubitril", "natriuresis", "degradation", "information", "supervision", "hypotension", "sterisonline", "sterispharma", "hyperkalemia", "vasodilation", "side effects", "crucial role", "CALL/WHATSAPP", "fluid balance", "blood vessels", "dose titration", "AT1) receptors", "blood pressure", "dual inhibition", "adverse effects", "pathophysiology", "hospitalization", "vasoconstrictor", "standard therapy", "renal impairment", "Clinical studies", "symptomatic HFrEF", "superior efficacy", "different pathways", "cardiac remodeling", "combination therapy", "deleterious effects", "innovative approach", "traditional therapy", "treatment guidelines", "neprilysin inhibitor", "cardiovascular death", "natriuretic peptides", "angiotensin II type 1", "aldosterone secretion", "two active ingredients", "combination medication", "cardiovascular outcomes", "cardiovascular benefits", "healthcare professional", "reduced ejection fraction", "New York Heart Association", "angiotensin receptor blockers", "angiotensin II receptor blocker", "NYHA) class II-IV heart failure", "renin-angiotensin-aldosterone system", "angiotensin-converting enzyme (ACE) inhibitors" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1279, "imageuri": "https://productimages.withfloats.com/actual/665ee8c06030c166b1a41ef3.png", "tileimageuri": "https://productimages.withfloats.com/tile/665ee8c06030c166b1a41ef3.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-04T10:13:18.717Z", "updatedon": "2026-03-16T10:01:51.784Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//-sacubright-200-/1279", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Sacubitril (97mg), Valsartan (103mg)", "category": "CARDIOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }