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{ "products": [ { "_id": "693c0c9c0c30ac5c9f8203b4", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide Mononitrate IP 30mg Tablets", "description": "CARDULES ISMN SR 30 tablets provide sustained-release Isosorbide Mononitrate IP 30mg, a nitrate medication designed for long-term management of angina in patients with coronary artery disease. This formulation from Steris Healthcare Pvt Ltd ensures steady vasodilation to improve heart blood flow and reduce chest pain episodes. It supports daily activities by minimizing oxygen demand on the heart muscle.​\nProduct Overview\nCARDULES ISMN SR 30 contains Isosorbide Mononitrate IP 30mg in a sustained-release matrix, allowing once-daily dosing for consistent therapeutic levels over 12-24 hours. The tablet's extended-release technology prevents peak-trough fluctuations common in immediate-release forms, promoting better patient compliance. Each film-coated tablet delivers precise bioavailability, with the active metabolite nitric oxide activating guanylate cyclase to boost cyclic GMP, relaxing vascular smooth muscle primarily in veins.​\n\nThis mechanism reduces preload (venous return to the heart) and afterload (arterial resistance), easing cardiac workload without significantly affecting heart rate. Unlike short-acting nitrates for acute relief, CARDULES ISMN SR 30 targets prophylaxis in chronic stable angina, often prescribed alongside beta-blockers or calcium channel blockers. Available in strips of 10 tablets, it undergoes rigorous quality testing at Steris facilities to meet IP standards, ensuring purity and stability.​\n\nKey Uses\nCARDULES ISMN SR 30 primarily prevents angina pectoris in coronary artery disease, where narrowed vessels limit oxygen supply during exertion. Patients experience fewer chest pain attacks during walking, climbing stairs, or stress.​\n\nIt manages chronic stable angina by enhancing myocardial perfusion, suitable for long-term therapy in adults over 18. Healthcare providers may use it adjunctively for coronary spasm or post-myocardial infarction prophylaxis to stabilize symptoms.​\n\nIn select cases, it aids heart failure management by offloading the heart, though not as monotherapy. Always initiate under cardiology supervision with dose titration to tolerance.​\n\nMajor Benefits\nThe sustained-release profile offers 24-hour protection with single morning dosing, improving adherence and lifestyle quality for active patients. It boosts exercise tolerance by 20-30% in trials, allowing longer physical efforts without angina onset.​\n\nBy dilating vessels, it decreases ischemia risk, potentially lowering hospitalization rates for acute episodes. Compared to placebo, users report halved attack frequency within weeks, enhancing daily productivity and emotional well-being.​\n\nBenefit\tMechanism\tPatient Outcome\nAngina Prevention\tVasodilation reduces preload/afterload ​\tFewer attacks, better exertion capacity\nSteady Relief\tSR formulation maintains levels ​\tOnce-daily convenience, no fluctuations\nHeart Protection\tImproves O2 delivery ​\tReduced ischemia, enhanced QoL\nCompliance Boost\tSimple regimen ​\tHigher adherence vs multiple doses\nAdditional perks include minimal impact on blood pressure in normotensives and compatibility with anti-anginals, making it versatile in combo therapy.\n\nPotential Side Effects\nCommon effects include headache (dose-related, often transient in first week), dizziness, or flushing due to vasodilation—hydrate and rise slowly to manage. Gastrointestinal upset like nausea occurs in 5-10% initially.​\n\nOrthostatic hypotension risks fainting, especially early; avoid alcohol or other vasodilators. Rare serious issues encompass severe hypotension, tachycardia, or methemoglobinemia with overdose—monitor blood pressure regularly.​\n\nAllergic reactions (rash, itching) or vision changes warrant discontinuation. Contraindicated in hypotension, glaucoma, or recent PDE5 inhibitor use; caution in anemia or hypothyroidism.​\n\nDosage Guidelines\nStart with 30mg once daily upon waking, swallowed whole without crushing. Titrate to 60mg if tolerated after 3-7 days, max 120mg/day. Take on empty stomach for optimal absorption; avoid late dosing to prevent nocturnal headaches.​\n\nAdjust for elderly or renal/hepatic impairment. Tolerance may develop—nitrate-free interval (evening) helps sustain efficacy. Store below 30°C.​\nConclusion\nCARDULES ISMN SR 30 empowers angina patients with reliable, once-daily prevention, restoring confidence in routine activities under Steris Healthcare's quality assurance. Its targeted vasodilation balances efficacy and tolerability for sustained heart health", "price": 65.0, "discountamount": 19.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2243, "imageuri": "https://productimages.withfloats.com/actual/693c0ca6391a3fa44b0608d8.png", "tileimageuri": "https://productimages.withfloats.com/tile/693c0ca6391a3fa44b0608d8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-12T12:37:48.92Z", "updatedon": "2026-03-14T08:21:58.091Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/isosorbide-mononitrate-ip-30mg-tablets/2243", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CARDULES ISMN SR 30", "category": "", "tags": [ "Isosorbide Mononitrate IP 30mg Tablets", "coronary artery disease", "heart blood flow and reduce chest pain episodes", "oxygen demand on the heart muscle", "relaxing vascular smooth muscle primarily in veins" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69142bf71d499513a92e5772", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nicorandil Tablets 5mg", "description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.", "price": 381.0, "discountamount": 115.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2202, "imageuri": "https://productimages.withfloats.com/actual/69142c03b53db80943abd33d.png", "tileimageuri": "https://productimages.withfloats.com/tile/69142c03b53db80943abd33d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T06:40:55.795Z", "updatedon": "2026-03-16T08:18:00.245Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//nicorandil-tablets-5mg/2202", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MAYORANDIL 5 ", "category": "CARDIOLOGYRANGE", "tags": [ "nicorandil tablets 5mg", "nicorandil 5 mg tablets uses", "nicorandil tablet 5mg benefits", "nicorandil 5mg medicine", "nicorandil tablets ip 5 mg", "what is nicorandil 5mg used for", "how does nicorandil tablet work", "nicorandil 5mg mechanism of action", "nicorandil tablets for angina treatment", "nicorandil tablet uses in heart disease", "nicorandil 5mg tablet price in india", "buy nicorandil 5mg tablets online", "nicorandil 5mg tablet brands", "nicorandil tablets manufacturer", "nicorandil tablets wholesale supplier" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "681b331b233d4ecb404fe2d7", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide Mononitrate 10 mg", "description": "CARDULES ISMN 10 is a prescription medication formulated to effectively manage and prevent angina pectoris (chest pain) associated with coronary artery disease. This medicine contains Isosorbide Mononitrate (10 mg), a long-acting nitrate that helps reduce the frequency and severity of anginal episodes. It is commonly prescribed as part of a long-term treatment plan for individuals with stable angina and other cardiovascular conditions to improve heart efficiency and blood flow.\n\nKey Ingredients\nIsosorbide Mononitrate 10 mg\nIsosorbide Mononitrate is the active nitrate component in this medicine, known for its vasodilatory effects that relax blood vessels and ease the heart’s workload. It is a metabolite of isosorbide dinitrate and offers longer-lasting therapeutic benefits with fewer doses.\n\nKey Benefits\nPrevents Chest Pain (Angina): CARDULES ISMN 10 is effective in reducing the number and severity of angina attacks by improving blood flow to the heart muscle.\n\nImproves Blood Circulation: The vasodilatory action of Isosorbide Mononitrate widens the arteries and veins, facilitating better circulation and oxygen delivery.\n\nReduces Heart Workload: By dilating blood vessels, the medication decreases the heart's oxygen demand, allowing it to function more efficiently.\n\nEnhances Exercise Tolerance: Patients using this medication often experience an increase in exercise capacity, as the risk of angina during physical activity is significantly reduced.\n\nLong-Acting Relief: As a sustained nitrate, CARDULES ISMN 10 provides long-lasting protection against anginal attacks when taken regularly.\n\nHow Does It Work?\nIsosorbide Mononitrate works by releasing nitric oxide in the smooth muscle cells of blood vessels. This nitric oxide activates an enzyme called guanylate cyclase, which increases cyclic guanosine monophosphate (cGMP). The rise in cGMP levels leads to the relaxation of vascular smooth muscles, causing vasodilation. This process reduces the amount of work the heart must do and lowers myocardial oxygen consumption. As a result, blood flows more easily, and the frequency of chest pain episodes is reduced. This mechanism makes CARDULES ISMN 10 a highly effective drug in the prevention of angina.\n\nDirections for Use\nTake CARDULES ISMN 10 strictly as prescribed by your doctor.\nIt is typically taken once or twice daily, depending on the severity of the condition and the prescribing physician's guidance.\nSwallow the tablet whole with a glass of water, preferably on an empty stomach or as directed.\nDo not crush, chew, or break the tablet, as it may interfere with the drug’s effectiveness.\nFor best results, take it at the same time each day to maintain consistent blood levels.\nAvoid abrupt discontinuation of the medication unless advised by your healthcare provider.\n\nSide Effects\nWhile CARDULES ISMN 10 is generally well-tolerated, some individuals may experience side effects, especially when starting treatment or adjusting dosage. Common and less serious side effects include:\n\nHeadache\n\nDizziness or light-headedness\n\nFlushing (warmth, redness, or tingly feeling under the skin)\n\nNausea\n\nFatigue\n\nIn rare cases, more serious side effects may occur, such as:\n\nSevere hypotension (low blood pressure)\n\nFainting\n\nIrregular heartbeat\n\nAllergic reactions like rash, itching, or swelling\n\nIf any severe or unusual side effects occur, seek immediate medical attention. Regular monitoring and dose adjustments may help manage and minimize side effects.", "price": 25.0, "discountamount": 8.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "commonly prescribed", "effectively manage", "angina directions", "medication decreases", "angina attacks", "stable angina", "dose adjustments", "rash itching", "rare cases", "tingly feeling", "headache dizziness", "generally welltolerated", "cardules ismn 10", "drugs effectiveness", "crush chew", "empty stomach", "water preferably", "daily depending", "process reduces", "anginal attacks", "longlasting protection", "physical activity", "exercise capacity", "veins facilitating", "vasodilatory action", "hearts workload", "cardiovascular conditions", "helps reduce", "vasodilatory effects", "starting treatment", "isosorbide dinitrate", "anginal episodes", "longacting nitrate", "side effects", "blood vessels", "experience side effects", "prescription medication formulated", "minimize side effects", "highly effective drug", "improve heart efficiency", "dilating blood vessels", "relax blood vessels", "chest pain episodes", "isosorbide mononitrate widens", "active nitrate component", "longterm treatment plan", "result blood flows", "improving blood flow", "skin nausea fatigue", "adjusting dosage common", "cgmp levels leads", "nitric oxide activates", "smooth muscle cells", "releasing nitric oxide", "coronary artery disease" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2105, "imageuri": "https://productimages.withfloats.com/actual/681b331ec4193dc2e4e9a77a.png", "tileimageuri": "https://productimages.withfloats.com/tile/681b331ec4193dc2e4e9a77a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-05-07T10:16:59.84Z", "updatedon": "2026-03-13T08:53:37.604Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//isosorbide-mononitrate-10-mg/2105", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CARDULES ISMN 10", "category": "CARDIOLOGYRANGE", "tags": [ "Isosorbide Mononitrate 10 mg Uses in Hindi", "Isosorbide 10 mg uses", "Isosorbide mononitrate 120 mg" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "681b2e1131166af9fb0be5c3", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide Dinitrate 5mg", "description": "CARDULES ISDN 5 is a prescription medication formulated with Isosorbide Dinitrate (5 mg), a well-known nitrate used to prevent and treat chest pain (angina) caused by coronary artery disease. This medicine is commonly prescribed to improve blood flow to the heart and reduce the frequency and severity of anginal attacks. It works by relaxing the blood vessels, making it easier for the heart to pump blood, and reducing its oxygen demand. CARDULES ISDN 5 is especially useful for long-term management of chronic angina and can be an essential part of a comprehensive cardiac care plan.\n\nKey Ingredients\nIsosorbide Dinitrate (5 mg) – This is the active pharmaceutical ingredient in CARDULES ISDN 5. Belonging to the nitrate class of drugs, Isosorbide Dinitrate helps widen and relax blood vessels, thereby improving blood flow and oxygen delivery to the heart muscle.\n\nKey Benefits\nProvides effective relief from angina (chest pain)\n\nHelps prevent angina episodes when taken regularly\n\nImproves blood circulation to the heart\n\nReduces the heart's workload and oxygen demand\n\nSupports overall cardiac function in patients with coronary artery disease\n\nCan improve exercise tolerance and reduce anginal frequency\n\nHow Does It Work?\nCARDULES ISDN 5 works by releasing nitric oxide within the vascular smooth muscle, leading to the relaxation of blood vessels. This vasodilation effect reduces the amount of work the heart must do to pump blood and lowers its oxygen demand. By widening the arteries and veins, Isosorbide Dinitrate facilitates better oxygen delivery to the heart tissue, which helps prevent angina attacks. It is especially effective in preventing episodes when used on a regular schedule, rather than providing immediate relief during an ongoing attack.\n\nDirections for Use\nAlways take CARDULES ISDN 5 exactly as prescribed by your physician.\n\nTypically taken orally, with or without food.\n\nIt is important to take the medication at the same times each day to maintain consistent nitrate levels in the bloodstream.\n\nSwallow the tablet whole with water; do not crush or chew unless advised.\n\nDo not stop the medication abruptly without consulting your doctor, as it may worsen angina symptoms.\n\nSide Effects\nWhile CARDULES ISDN 5 is generally well-tolerated, some individuals may experience side effects. These can include:\n\nHeadache (commonly occurs initially and often subsides with continued use)\n\nDizziness or light-headedness, especially when rising from a sitting or lying position\n\nNausea or vomiting\n\nFlushing or warmth of the skin\n\nLow blood pressure (hypotension)\n\nRapid heartbeat (tachycardia)\n\nIn rare cases, allergic reactions or more serious cardiovascular effects may occur. Always report any persistent or severe side effects to your healthcare provider immediately.\n\n", "price": 8.0, "discountamount": 2.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "effective relief", "heart tissue", "commonly prescribed", "heart reduces", "vomiting flushing", "generally welltolerated", "medication abruptly", "bloodstream swallow", "physician typically", "cardules ismn 5", "regular schedule", "preventing episodes", "cardiac function", "hearts workload", "nitrate class", "essential part", "chronic angina", "longterm management", "wellknown nitrate", "oxygen delivery", "anginal attacks", "pump blood", "cardiovascular effects", "oxygen demand", "blood vessels", "reduce anginal frequency", "oxygen demand supports", "prescription medication formulated", "relax blood vessels", "blood vessels making", "vasodilation effect reduces", "improving blood flow", "improve blood flow", "severe side effects", "experience side effects", "healthcare provider immediately", "lying position nausea", "ongoing attack directions", "releasing nitric oxide", "improve exercise tolerance", "active pharmaceutical ingredient", "coronary artery disease" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2104, "imageuri": "https://productimages.withfloats.com/actual/681b2e1454203247c379193a.png", "tileimageuri": "https://productimages.withfloats.com/tile/681b2e1454203247c379193a.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-05-07T09:55:29.776Z", "updatedon": "2026-05-08T10:24:58.799Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//isosorbide-dinitrate-5mg/2104", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CARDULES ISDN 5", "category": "CARDIOLOGYRANGE", "tags": [ "Isosorbide dinitrate 5 mg uses", "Isosorbide dinitrate uses", "Isosorbide Dinitrate 5 mg price", "Isosorbide dinitrate dosage", "isosorbide dinitrate 5mg", "isosorbide dinitrate 5mg tab", "isosorbide dinitrate 5mg price", "isosorbide dinitrate 5mg uses" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "67f65a7ceb61400ce2dc1154", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide Mononitrate 50 mg", "description": "CARDULES ISMN SR 50 is a sustained-release tablet formulated with Isosorbide Mononitrate (50 mg), a nitrate-class medication widely used for the prevention and long-term management of angina pectoris (chest pain caused by heart disease). This medicine works by relaxing and widening the blood vessels, ensuring an adequate oxygen supply to the heart muscles and reducing the workload on the heart. It is primarily prescribed to individuals suffering from coronary artery disease or chronic stable angina.\n\n\nKey Benefits:\n\n\nPrevents angina attacks by increasing oxygen delivery to the heart muscles.\n\nImproves blood circulation by dilating the blood vessels, especially in the heart.\n\nReduces the workload on the heart, making it easier for patients with heart conditions to engage in daily activities.\n\nSustained-release formulation provides longer-lasting relief and maintains consistent therapeutic levels in the bloodstream.\n\nHelps manage chronic chest pain and enhances the overall quality of life in patients with heart-related conditions.\n\n\nHow Does It Work?\n\n\nIsosorbide Mononitrate, the active component in CARDULES ISMN SR 50, is a nitrate that undergoes biotransformation to release nitric oxide (NO), a natural vasodilator. Nitric oxide activates guanylate cyclase, leading to the production of cyclic GMP, which relaxes the smooth muscles of the blood vessels. This action reduces preload and afterload, lowering the heart's oxygen demand and preventing anginal episodes. The sustained-release mechanism ensures a steady release of the drug over time, providing prolonged therapeutic effects and reducing the frequency of dosing.\n\n\nDirections for Use:\n\n\nCARDULES ISMN SR 50 should be taken once daily, preferably in the morning after a light meal.\n\nSwallow the tablet whole with a glass of water. Do not crush or chew.\n\nFollow your healthcare provider's instructions regarding dosage and duration.\n\nAvoid abrupt discontinuation without consulting your doctor.\n\nMaintain a nitrate-free interval of 10-- 12 hours daily (as advised) to prevent tolerance buildup.\n\n\nSide Effects:\n\n\nWhile CARDULES ISMN SR 50 is generally well-tolerated, some individuals may experience:\n\nHeadache-- Common and usually resolves with continued use.\n\nDizziness or lightheadedness-- Especially when getting up from a sitting or lying position.\n\nFlushing or warmth in the face\n\nLow blood pressure (hypotension).\n\nNausea or vomiting.\n\nFatigue or weakness.\n\nSeek immediate medical attention if you experience severe allergic reactions, chest pain that worsens, or signs of low blood pressure such as fainting or vision changes.", "price": 136.0, "discountamount": 41.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "individuals suffering", "heart conditions", "heart making", "heart muscles", "medical attention", "weakness seek", "vomiting fatigue", "generally welltolerated", "nitratefree interval", "doctor maintain", "chew follow", "daily preferably", "dosing directions", "afterload lowering", "smooth muscles", "cyclic gmp", "undergoes biotransformation", "active component", "heartrelated conditions", "longerlasting relief", "primarily prescribed", "medicine works", "longterm management", "heart reduces", "heart disease", "steady release", "blood vessels", "blood vessels ensuring", "sustainedrelease tablet formulated", "low blood pressure", "action reduces preload", "release nitric oxide", "coronary artery disease", "lying position flushing", "experience headache common", "healthcare providers instructions", "light meal swallow", "sustainedrelease mechanism ensures", "preventing anginal episodes", "hearts oxygen demand", "work isosorbide mononitrate", "increasing oxygen delivery", "adequate oxygen supply", "nitrateclass medication widely" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2079, "imageuri": "https://productimages.withfloats.com/actual/692a8c6d366a1fddbaa87d71.png", "tileimageuri": "https://productimages.withfloats.com/tile/692a8c6d366a1fddbaa87d71.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-04-09T11:31:08.191Z", "updatedon": "2026-03-13T09:01:21.799Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//isosorbide-mononitrate-50-mg/2079", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CARDULES ISMN SR 50", "category": "CARDIOLOGYRANGE", "tags": [ "Isosorbide mononitrate 60 mg", "Isosorbide mononitrate uses", "Isosorbide mononitrate side effects" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "67f65773416f03578685810d", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide Mononitrate 40 mg", "description": "CARDULES ISMN SR 40 is a sustained-release tablet formulated with Isosorbide Mononitrate (40 mg), a powerful nitrate-based compound used primarily in the prevention and long-term management of angina pectoris (chest pain caused by heart disease). This medication works by relaxing and widening blood vessels, allowing for improved blood flow to the heart, reducing its workload, and preventing episodes of chest pain. It is typically prescribed for patients with chronic stable angina and forms part of a long-term treatment plan for certain heart conditions.\n\n\nKey Benefits:\n\n\nHelps prevent and manage angina (chest pain) in patients with coronary artery disease.\n\nImproves blood flow to the heart muscles, reducing the risk of cardiac ischemia.\n\nDecreases the oxygen demand on the heart by reducing preload and afterload.\n\nOffers long-lasting relief with a sustained-release action for convenience and steady plasma levels.\n\nReduces the frequency of anginal attacks, enhancing quality of life and exercise tolerance.\n\n\nHow Does It Work?\n\n\nIsosorbide Mononitrate, the active ingredient in CARDULES ISMN SR 40, is converted into nitric oxide in the body. Nitric oxide activates guanylate cyclase, leading to increased levels of cyclic GMP (cGMP). This compound causes relaxation of vascular smooth muscles, primarily in the veins and arteries, resulting in vasodilation. As a result, blood flows more freely to the heart with reduced pressure, decreasing the heart's workload and helping to prevent episodes of angina. The sustained-release formulation ensures a prolonged therapeutic effect, minimizing fluctuations in drug levels throughout the day.\n\nDirections for Use\nTake CARDULES ISMN SR 40 exactly as prescribed by your doctor.\n\nSwallow the tablet whole with a glass of water, preferably at the same time each day.\n\nDo not crush, chew, or break the tablet as it is designed for slow release over time.\n\nIt is typically taken once daily, but the dosage may vary depending on individual medical conditions.\n\nAvoid taking the tablet on an empty stomach unless advised by your healthcare provider.\n\nDo not suddenly stop taking the medication without consulting your doctor.\n\n\nSide Effects:\n\n\nLike all medications, CARDULES ISMN SR 40 may cause some side effects, although not everyone experiences them. Common side effects include:\n\nHeadache (especially at the beginning of treatment).\n\nDizziness or lightheadedness.\n\nFlushing of the skin.\n\nNausea or vomiting.\n\nFatigue.\n\nLow blood pressure (hypotension).\n\nIn rare cases, severe allergic reactions or fainting may occur. Contact your healthcare provider immediately if you experience chest pain that doesn't improve, irregular heartbeat, or signs of an allergic reaction like rash, itching, or swelling.", "price": 73.0, "discountamount": 22.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "typically prescribed", "day directions", "hearts workload", "medication works", "heart disease", "rash itching", "allergic reaction", "occur contact", "skin nausea", "lightheadedness flushing", "empty stomach", "vary depending", "slow release", "crush chew", "water preferably", "drug levels", "prevent episodes", "arteries resulting", "increased levels", "nitric oxide", "active ingredient", "exercise tolerance", "oxygen demand", "forms part", "preventing episodes", "heart reducing", "reducing preload", "treatment dizziness", "doctor swallow", "longterm management", "sustainedrelease action", "healthcare provider", "chest pain", "side effects", "heart muscles reducing", "sustainedrelease tablet formulated", "doctor side effects", "experience chest pain", "healthcare provider immediately", "longterm treatment plan", "chronic stable angina", "powerful nitratebased compound", "common side effects", "sustainedrelease formulation ensures", "suddenly stop taking", "reduced pressure decreasing", "result blood flows", "cyclic gmp cgmp", "work isosorbide mononitrate", "cardiac ischemia decreases", "improved blood flow" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2078, "imageuri": "https://productimages.withfloats.com/actual/67f657744062f07a5185c6ad.png", "tileimageuri": "https://productimages.withfloats.com/tile/67f657744062f07a5185c6ad.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-04-09T11:18:11.501Z", "updatedon": "2026-03-13T09:00:04.488Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//isosorbide-mononitrate-40-mg/2078", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CARDULES ISMN SR 40", "category": "CARDIOLOGYRANGE", "tags": [ "What is isosorbide mononitrate 30 mg used for", "Isosorbide mononitrate 10mg", "Isosorbide mononitrate 30 mg side effects", "Isosorbide mononitrate 5 mg" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "665db060a743fd235821c9e8", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nicorandil Tablets 5mg", "description": "Heart health is a critical aspect of overall well-being, and managing cardiovascular conditions effectively can significantly improve quality of life. Nicorandil Tablets 5mg are widely prescribed for the prevention and treatment of chronic stable angina, a condition characterized by chest pain caused by reduced blood flow to the heart muscles. Nicorandil is a unique anti-anginal medication that works through dual mechanisms to improve oxygen supply to the heart while reducing its workload.\n\nFor patients experiencing recurring chest discomfort, tightness, or angina symptoms, Nicorandil Tablets 5mg offer a proven therapeutic option that helps improve exercise tolerance, reduce angina attacks, and enhance daily activities. This comprehensive guide explains everything you need to know about Nicorandil 5mg, including its uses, mechanism of action, benefits, dosage, side effects, and precautions.\n\nWhat Are Nicorandil Tablets 5mg?\n\nNicorandil Tablets 5mg contain Nicorandil, a vasodilator medication used primarily for the management of chronic stable angina pectoris. It is particularly beneficial for patients who do not achieve adequate symptom control with conventional anti-anginal therapies or who require additional treatment support.\n\nNicorandil improves blood flow to the heart by widening blood vessels and reducing cardiac workload. This dual-action mechanism helps prevent chest pain episodes and improves overall cardiovascular function.\n\nHow Nicorandil Tablets 5mg Work\n\nNicorandil has a unique dual mechanism of action that distinguishes it from many other anti-anginal medications.\n\nNitrate-Like Action\n\nNicorandil acts similarly to nitrates by relaxing smooth muscles in blood vessel walls.\n\nThis action:\n\nDilates coronary arteries\nImproves blood flow to the heart\nIncreases oxygen delivery to cardiac tissues\nReduces chest pain episodes\nPotassium Channel Activation\n\nNicorandil also activates ATP-sensitive potassium channels.\n\nThis leads to:\n\nRelaxation of arterial blood vessels\nReduced vascular resistance\nLower cardiac workload\nImproved myocardial oxygen balance\n\nTogether, these mechanisms help reduce the frequency and severity of angina attacks while improving exercise capacity.\n\nKey Benefits of Nicorandil Tablets 5mg\n\nNicorandil 5mg provides several important cardiovascular benefits.\n\nEffective Angina Control\n\nHelps reduce the frequency and intensity of angina attacks.\n\nImproved Blood Flow\n\nEnhances coronary circulation and oxygen supply to the heart muscle.\n\nBetter Exercise Tolerance\n\nAllows patients to perform physical activities with reduced chest discomfort.\n\nReduced Cardiac Workload\n\nDecreases the heart's oxygen demand, reducing stress on the cardiovascular system.\n\nLong-Term Symptom Management\n\nSupports ongoing control of chronic stable angina symptoms.\n\nImproved Quality of Life\n\nPatients often experience better mobility, comfort, and daily functioning.\n\nWhy Nicorandil Tablets 5mg Are Important\n\nChronic stable angina occurs when the heart muscle does not receive sufficient oxygen-rich blood during periods of increased demand. Without proper treatment, angina can interfere with daily activities and may indicate underlying coronary artery disease.\n\nNicorandil helps:\n\nImprove oxygen supply to the heart\nReduce chest pain episodes\nEnhance physical performance\nSupport long-term cardiovascular management\nMinimize angina-related limitations\n\nFor many patients, Nicorandil serves as an important component of comprehensive heart disease management.\n\nIndications of Nicorandil Tablets 5mg\n\nNicorandil 5mg is commonly prescribed for:\n\nChronic Stable Angina\n\nThe primary indication for Nicorandil is prevention and management of chronic stable angina.\n\nInadequate Response to Conventional Therapy\n\nPatients who continue to experience symptoms despite standard anti-anginal medications may benefit from Nicorandil.\n\nCombination Therapy\n\nOften used alongside other cardiovascular medications for enhanced symptom control.\n\nCoronary Artery Disease Management\n\nSupports overall treatment strategies aimed at improving heart function and reducing ischemic symptoms.\n\nEfficacy and Clinical Evidence\n\nNumerous clinical studies have demonstrated the effectiveness of Nicorandil in managing chronic stable angina.\n\nReduced Angina Frequency\n\nResearch shows significant reductions in the number of weekly angina episodes among treated patients.\n\nImproved Exercise Performance\n\nPatients often experience increased exercise duration and improved physical activity tolerance.\n\nEnhanced Coronary Blood Flow\n\nClinical evidence supports Nicorandil’s ability to improve myocardial perfusion.\n\nSymptom Relief\n\nMany patients report fewer chest pain episodes and reduced dependence on rescue nitrate medications.\n\nThese findings support Nicorandil’s role as a valuable anti-anginal treatment option.\n\nWho Should Consider Nicorandil Tablets 5mg?\n\nNicorandil may be recommended for:\n\nAdults diagnosed with chronic stable angina\nPatients experiencing recurrent chest pain\nIndividuals requiring additional anti-anginal therapy\nPatients intolerant to certain conventional medications\nThose seeking improved exercise capacity and symptom control\n\nA cardiologist or healthcare provider can determine whether Nicorandil is appropriate based on individual cardiovascular health.\n\nDosage Guidelines for Nicorandil Tablets 5mg\n\nAlways follow your physician’s instructions regarding dosage.\n\nTypical Starting Dose\n\nMany patients begin treatment with:\n\nNicorandil 5mg twice daily\n\nThe dose may be adjusted based on symptom control and patient response.\n\nAdministration Instructions\nTake the tablet with water\nCan be taken with or without food\nTake at the same time each day\nDo not skip doses without medical advice\nMissed Dose\n\nIf a dose is missed:\n\nTake it as soon as remembered\nSkip it if the next dose is due soon\nDo not double the dose\nOverdose\n\nSeek immediate medical attention if overdose is suspected.\n\nSide Effects of Nicorandil Tablets 5mg\n\nLike all medications, Nicorandil may cause side effects in some patients.\n\nCommon Side Effects\nHeadache\nDizziness\nFlushing\nNausea\nWeakness\nLow blood pressure\n\nThese effects are often mild and may decrease as the body adjusts to treatment.\n\nSerious Side Effects of Nicorandil Tablets 5mg\n\nAlthough uncommon, serious adverse reactions may include:\n\nSevere hypotension\nPersistent dizziness\nUlcer formation (oral, gastrointestinal, or skin ulcers)\nRapid heartbeat\nAllergic reactions\nSevere chest pain worsening\n\nPatients experiencing serious symptoms should seek immediate medical care.\n\nPrecautions and Warnings\n\nBefore using Nicorandil Tablets 5mg, discuss your medical history with your healthcare provider.\n\nLow Blood Pressure\n\nNicorandil may further lower blood pressure in susceptible individuals.\n\nHeart Conditions\n\nPatients with severe cardiovascular disorders require careful monitoring.\n\nKidney and Liver Disease\n\nDose adjustments may be necessary in certain patients.\n\nPregnancy and Breastfeeding\n\nUse only if prescribed by a healthcare professional after evaluating benefits and risks.\n\nAlcohol Consumption\n\nAlcohol may increase dizziness and blood pressure-lowering effects.\n\nDrug Interactions\n\nInform your doctor if you take:\n\nBlood pressure medications\nNitrate preparations\nErectile dysfunction medications\nDiuretics\nCardiovascular drugs\n\nCertain combinations may increase the risk of hypotension.\n\nStorage Instructions\n\nTo maintain product quality:\n\nStore below recommended temperatures\nKeep away from moisture and direct sunlight\nKeep out of reach of children\nStore in original packaging\n\nProper storage helps preserve medication effectiveness.\n\nWhy Choose Nicorandil Tablets 5mg?\n\nNicorandil offers several advantages for patients managing chronic stable angina:\n\nDual mechanism of action\nEffective symptom relief\nImproved exercise tolerance\nEnhanced coronary blood flow\nReduced frequency of angina attacks\nConvenient oral dosing\nProven clinical efficacy\n\nThese benefits make Nicorandil an important therapeutic option in modern cardiovascular care.\n\nConclusion\n\nNicorandil Tablets 5mg provide an effective and clinically proven solution for the prevention and management of chronic stable angina. Through its unique dual mechanism of action, Nicorandil improves blood flow to the heart, reduces cardiac workload, and helps patients experience fewer angina episodes while maintaining a more active lifestyle.\n\nFor individuals seeking reliable symptom control and improved cardiovascular performance, Nicorandil 5mg remains a trusted treatment option prescribed by healthcare professionals worldwide. Consistent use under medical supervision can significantly contribute to better heart health, enhanced exercise capacity, and improved quality of life.\n\nFrequently Asked Questions (FAQs)\n1. What are Nicorandil Tablets 5mg used for?\n\nNicorandil Tablets 5mg are primarily used to prevent and manage chronic stable angina (chest pain caused by reduced blood flow to the heart).\n\n2. How does Nicorandil work?\n\nNicorandil widens blood vessels through nitrate-like effects and potassium channel activation, improving oxygen delivery to the heart and reducing cardiac workload.\n\n3. How long does it take for Nicorandil to work?\n\nMany patients begin experiencing benefits within a short period after starting treatment, although full symptom control may take longer depending on individual response.\n\n4. Can Nicorandil be taken with other heart medications?\n\nYes, Nicorandil is often prescribed alongside other cardiovascular medications, but only under medical supervision.\n\n5. What are the most common side effects of Nicorandil?\n\nCommon side effects include headache, dizziness, flushing, nausea, and low blood pressure.\n\n6. Is Nicorandil Tablets 5mg safe for long-term use?\n\nWhen prescribed and monitored by a healthcare professional, Nicorandil is generally considered safe and effective for long-term angina management.", "price": 274.0, "discountamount": 83.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "Call", "Uses", "Email", "ORDER", "flushing", "WhatsApp", "workload", "Treatment", "dizziness", "headaches", "Nicorandil", "medication", "management", "individual", "heart rate", "blood flow", "Conclusion", "chest pain", "MAYORANDIL", "Precautions", "supplements", "information", "sterispharma", "sterisonline", "complete list", "blood vessels", "angina pectoris", "recommended dose", "heart conditions", "regular monitoring", "low blood pressure", "medical conditions", "allergic reactions", "5mg dosage strength", "Common side effects", "dosage instructions", "healthcare provider", "medical supervision", "Serious side effects", "therapeutic response", "sudden discontinuation", "healthcare professional", "gastrointestinal symptoms", "other cardiovascular conditions" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1244, "imageuri": "https://productimages.withfloats.com/actual/665db060ca75628a5851f8b0.png", "tileimageuri": "https://productimages.withfloats.com/tile/665db060ca75628a5851f8b0.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-03T12:00:32.116Z", "updatedon": "2026-06-02T12:11:49.871Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//nicorandil-tablets-5mg/1244", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MAYORANDIL 5", "category": "CARDIOLOGYRANGE", "tags": [ "nicorandil tablets 5mg", "nicorandil tablets 5mg uses in hindi", "nicorandil tablets 5mg uses", "nicorandil tablets 5mg price", "nicorandil tablets 5mg uses in english", "nicorandil 5mg tablet", "t nicorandil 5mg", "nicorandil 5mg tablets" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6a6def248b0777b5cb29791c", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Propranolol Hydrochloride Sustained Release Capsules IP", "description": "PROPASULES LA 40 is a premium pharmaceutical formulation containing Propranolol Hydrochloride Sustained Release Capsules IP 40 mg. Developed with advanced sustained-release technology, this formulation delivers the active ingredient gradually over an extended period, helping maintain consistent therapeutic levels while supporting the convenience of once-daily administration when prescribed by a healthcare professional.\n\nManufactured in GMP-certified facilities using pharmaceutical-grade raw materials, PROPASULES LA 40 is produced under strict quality control measures to ensure purity, safety, and batch-to-batch consistency. It is intended for the treatment of medical conditions in which propranolol therapy is considered appropriate by a qualified physician.\n\nComposition\n\nEach Sustained Release Capsule Contains:\n\nPropranolol Hydrochloride IP – 40 mg\nSustained Release Pellets\nPharmaceutical Excipients – q.s.\nCapsule Shell – Approved pharmaceutical-grade ingredients\n\nDosage Form: Sustained Release Capsules\n\nWhat is PROPASULES LA 40?\n\nPROPASULES LA 40 contains Propranolol Hydrochloride, a non-selective beta-adrenergic receptor blocker (beta-blocker) that helps manage a variety of cardiovascular and neurological conditions. The sustained-release formulation is specifically designed to release the medicine gradually throughout the day, providing prolonged therapeutic action and helping maintain stable plasma drug concentrations compared with conventional immediate-release formulations.\n\nIts controlled-release technology enhances dosing convenience and supports consistent treatment outcomes when used according to medical advice.\n\nKey Features\nContains Propranolol Hydrochloride Sustained Release IP 40 mg\nAdvanced sustained-release technology for prolonged drug delivery\nSupports once-daily dosing as prescribed\nManufactured using premium pharmaceutical-grade ingredients\nProduced in GMP-compliant manufacturing facilities\nStringent quality assurance for consistent product performance\nReliable formulation for long-term therapeutic use under medical supervision\nTherapeutic Uses\n\nHealthcare professionals may prescribe PROPASULES LA 40 for the management of several cardiovascular and neurological disorders, including:\n\nHypertension (high blood pressure)\nChronic stable angina\nCardiac arrhythmias\nPrevention of migraine attacks\nEssential tremor\nPhysical symptoms associated with anxiety\nCardiovascular manifestations of hyperthyroidism\nSecondary prevention following myocardial infarction, when clinically indicated\n\nThe choice of treatment, dosage, and duration should always be individualized based on the patient's medical condition and physician's assessment.\n\nHow PROPASULES LA 40 Works\n\nPropranolol Hydrochloride works by blocking beta-adrenergic receptors located in the heart and other tissues. This action reduces the effects of adrenaline and other stress hormones on the cardiovascular system.\n\nAs a result, the medicine may help:\n\nSlow the heart rate\nReduce the workload on the heart\nLower elevated blood pressure\nImprove control of certain abnormal heart rhythms\nReduce the frequency of migraine episodes\nMinimize symptoms associated with essential tremor\nRelieve physical manifestations of anxiety, such as rapid heartbeat and trembling\n\nThe sustained-release pellets gradually release the medication throughout the day, providing prolonged therapeutic coverage and reducing fluctuations in drug levels.\n\nBenefits of the Sustained Release Formulation\n\nThe advanced sustained-release technology offers several advantages:\n\nControlled and gradual release of the active ingredient\nExtended therapeutic effect throughout the dosing interval\nMore consistent blood concentrations of the medication\nReduced peak-to-trough fluctuations compared with immediate-release formulations\nConvenient dosing schedule that may improve treatment adherence\nSuitable for long-term therapy under medical supervision\n\nTreatment outcomes depend on individual patient response and adherence to the prescribed regimen.\n\nDosage and Administration\n\nTake PROPASULES LA 40 exactly as instructed by your healthcare provider.\n\nGeneral recommendations include:\n\nSwallow the capsule whole with sufficient water.\nDo not crush, chew, or open the capsule unless specifically advised.\nTake the medicine at the same time every day.\nFollow the prescribed dosage schedule carefully.\nDo not discontinue treatment abruptly without consulting your physician, as sudden withdrawal may increase the risk of cardiovascular complications.\nPossible Side Effects\n\nLike all medications, PROPASULES LA 40 may cause side effects in some individuals, although many patients tolerate it well.\n\nCommon side effects may include:\n\nFatigue\nDizziness\nSlow heartbeat\nCold hands and feet\nNausea\nSleep disturbances\nMild stomach discomfort\n\nSeek immediate medical attention if you experience breathing difficulty, severe dizziness, fainting, swelling of the face or throat, or signs of a serious allergic reaction.\n\nConsult your healthcare provider if any side effects persist or become troublesome.\n\nPrecautions and Warnings\n\nBefore starting PROPASULES LA 40, inform your doctor if you have:\n\nAsthma or chronic obstructive pulmonary disease (COPD)\nDiabetes mellitus\nLiver impairment\nKidney disease\nHeart failure\nLow blood pressure\nBradycardia (slow heart rate)\nPeripheral vascular disease\nThyroid disorders\nHistory of hypersensitivity reactions\n\nYour physician should also be informed about all prescription medicines, over-the-counter drugs, herbal supplements, and dietary products you are taking to minimize the risk of drug interactions.\n\nPregnancy and Breastfeeding\n\nThe use of PROPASULES LA 40 during pregnancy or breastfeeding should only be considered when recommended by a qualified healthcare professional after carefully evaluating the potential benefits and possible risks.\n\nAlways consult your physician before taking this medicine during pregnancy or while nursing.\n\nStorage Instructions\n\nTo maintain product quality:\n\nStore in a cool and dry place.\nProtect from moisture and direct sunlight.\nKeep below the storage temperature specified on the product label.\nStore in the original packaging until use.\nKeep out of the reach of children.\nDo not use the medicine after the expiry date printed on the pack.\nWhy Choose PROPASULES LA 40?\n\nPROPASULES LA 40 is formulated to deliver dependable therapeutic performance through advanced sustained-release technology. Manufactured under stringent pharmaceutical quality standards, it combines consistent drug delivery, convenient dosing, and reliable product quality to support long-term cardiovascular and neurological care.\n\nKey Advantages\n\nPremium sustained-release Propranolol formulation\nControlled drug release for prolonged therapeutic action\nConvenient once-daily administration as prescribed\nManufactured in GMP-certified facilities\nHigh standards of quality, purity, and consistency\nReliable formulation for chronic disease management\nFrequently Asked Questions (FAQs)\nWhat is PROPASULES LA 40 prescribed for?\n\nPROPASULES LA 40 may be prescribed for conditions such as hypertension, chronic angina, cardiac arrhythmias, migraine prevention, essential tremor, anxiety-related physical symptoms, and certain cardiovascular conditions, depending on the physician's evaluation.\n\nCan PROPASULES LA 40 be taken once a day?\n\nYes. The sustained-release formulation is designed to support convenient once-daily dosing when prescribed by a healthcare professional.\n\nCan I stop taking PROPASULES LA 40 suddenly?\n\nNo. Abrupt discontinuation of propranolol may increase the risk of serious cardiovascular events. Always consult your doctor before stopping treatment.\n\nCan people with diabetes take PROPASULES LA 40?\n\nPatients with diabetes should use this medicine only under medical supervision, as beta-blockers may mask some warning signs of low blood sugar.\n\nIs PROPASULES LA 40 suitable for every patient?\n\nNo. This medicine may not be appropriate for individuals with certain conditions such as severe asthma, significant bradycardia, or specific cardiac disorders. Your healthcare provider will determine whether it is suitable for your individual medical needs.", "price": 45.0, "discountamount": 14.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2490, "imageuri": "https://productimages.withfloats.com/actual/6a6def271f223d84dee2d962.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a6def271f223d84dee2d962.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-08-01T13:05:40.676Z", "updatedon": "2026-08-01T13:05:40.676Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//propranolol-hydrochloride-sustained-release-capsules-ip/2490", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "PROPASULES LA 40", "category": "CARDIOLOGYRANGE", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6a460bf90c11f3c74a816c87", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "methylprednisolone sodium succinate for injection usp", "description": "Methylprednisolone Sodium Succinate for Injection USP is a fast-acting corticosteroid administered intravenously or intramuscularly to control severe inflammation, allergic reactions, and autoimmune flare-ups. It works by rapidly suppressing the immune and inflammatory response and is used in hospital or clinical settings for acute conditions such as severe asthma attacks, anaphylaxis, autoimmune disease flares, and spinal cord injury protocols. It is a Schedule H prescription drug administered only under medical supervision.\n\nWhat Is Methylprednisolone Sodium Succinate for Injection USP?\n\nMethylprednisolone Sodium Succinate for Injection USP is a water-soluble, injectable corticosteroid used for rapid control of severe inflammatory, allergic, and autoimmune conditions. It is manufactured to United States Pharmacopeia (USP) standards and is typically administered by a healthcare professional via intravenous (IV) or intramuscular (IM) route when fast, high-potency anti-inflammatory or immunosuppressive action is required — situations where oral steroids act too slowly or oral intake isn't feasible.\n\nHow It Works\n\nMethylprednisolone sodium succinate is a synthetic glucocorticoid that acts rapidly once reconstituted and injected.\n\n\nBinds glucocorticoid receptors – enters cells and binds intracellular receptors that regulate inflammatory gene expression.\nSuppresses inflammatory mediators – reduces production of prostaglandins, leukotrienes, and cytokines responsible for swelling, redness, and pain.\nStabilizes cell membranes – reduces capillary permeability, limiting fluid leakage and tissue swelling at the site of inflammation.\nDampens immune overactivity – suppresses lymphocyte and macrophage activity, calming autoimmune or allergic overreactions.\nDelivers rapid systemic action – because it's water-soluble and given IV/IM, onset of anti-inflammatory effect is significantly faster than oral steroids.\n\n\nClinical Indications\n\nConditionWhy Methylprednisolone Injection Is UsedSevere Allergic Reactions / AnaphylaxisRapidly controls swelling, airway inflammation, and allergic cascadeAcute Asthma Exacerbation / COPD FlareReduces airway inflammation when inhalers alone are insufficientAutoimmune Disease Flares (Lupus, Rheumatoid Arthritis)High-dose pulse therapy to control acute flaresSpinal Cord Injury (acute, under specialist protocol)Used in specific clinical protocols to limit secondary inflammationSevere Dermatologic ReactionsControls widespread inflammatory skin reactionsPost-Transplant / Organ Rejection ManagementUsed as part of immunosuppressive regimens\n\nDosage & Administration\n\nParameterRecommendationTypical Adult Dose10–40 mg IV, may range up to 30 mg/kg in high-dose pulse therapy for specific conditionsRouteIntravenous (IV) injection/infusion or Intramuscular (IM) injectionFrequencyAs directed by the treating physician; often single dose or short tapering courseReconstitutionMust be reconstituted only with the accompanying diluent as per product insert, immediately before useAdministration SettingHospital, clinic, or under direct medical/nursing supervision onlyDurationShort-term acute use unless otherwise directed; long-term use requires specialist monitoring\n\nThis is a Schedule H prescription-only medicine. Dosage must be determined and administered by a qualified healthcare professional.\n\nPrecautions\n\n\nTo be administered only by or under the supervision of a healthcare professional.\nNot for self-administration or home use.\nInform the doctor of any active infections, as corticosteroids can mask symptoms and suppress immune response.\nUse with caution in patients with diabetes, hypertension, peptic ulcer disease, osteoporosis, or psychiatric history.\nAvoid live vaccines during treatment due to immunosuppressive effects.\nPregnant or breastfeeding patients should use only under strict medical guidance.\nAbrupt discontinuation after prolonged use should be avoided; tapering may be required as advised by the physician.\n\n\nPossible Side Effects\n\nMost side effects relate to the drug's systemic corticosteroid action and are monitored by the administering clinician:\n\n\nElevated blood sugar levels\nFluid retention, increased blood pressure\nMood changes, insomnia, or restlessness\nNausea or gastrointestinal discomfort\nIncreased susceptibility to infection\nInjection site reactions\n\n\nSerious side effects requiring immediate medical attention include severe allergic reaction, signs of infection (fever, chills), significant mood or behavioral changes, unusual swelling, or vision disturbances. Because this is administered in a clinical setting, the healthcare team monitors for these actively.\n\nComparison: Methylprednisolone vs. Other Injectable Corticosteroids\n\nDrugRelative PotencyCommon Use CaseRouteMethylprednisolone Sodium SuccinateHighAcute severe inflammation, autoimmune flaresIV/IMHydrocortisone Sodium SuccinateLowerAdrenal insufficiency, milder acute inflammationIV/IMDexamethasone Sodium PhosphateVery HighCerebral edema, severe allergic/inflammatory conditionsIV/IMBetamethasone Sodium PhosphateHighAllergic and inflammatory conditions, fetal lung maturityIV/IMTriamcinolone AcetonideModerate (depot)Localized/intra-articular inflammationIM/Intra-articular\n\nKey Statistics\n\nStatisticData PointSourceOnset of anti-inflammatory action after IV administrationWithin 1–2 hours for measurable effectClinical pharmacology references, USP monographUse in acute severe asthma protocolsRecommended as part of systemic corticosteroid therapy in emergency guidelinesGlobal Initiative for Asthma (GINA) guidelinesHospital use in anaphylaxis managementIncluded as an adjunct in anaphylaxis treatment protocols alongside epinephrineWorld Allergy Organization guidanceHigh-dose pulse therapy applicationUsed in select autoimmune flare protocols under specialist supervisionPublished rheumatology treatment guidelines\n\nExpert Insight\n\n[Insert verified physician or clinical pharmacologist commentary here — Claude has not fabricated a quote. Recommend sourcing a short, attributable statement from a Steris Healthcare medical advisor or a cited clinical guideline before publishing.]\n\nConclusion\n\nMethylprednisolone Sodium Succinate for Injection USP is a high-potency, fast-acting corticosteroid reserved for situations where rapid control of severe inflammation, allergic reaction, or autoimmune flare is essential. Administered only under clinical supervision, it plays a critical role in emergency and hospital-based treatment protocols — from anaphylaxis and acute asthma to autoimmune disease management. As a Schedule H medicine, it must never be self-administered; dosage, route, and duration should always be determined by a qualified physician based on the patient's condition. For pharmacopoeia-grade quality and reliable hospital supply, source this injection through a WHO-GMP certified manufacturer.\n\nPrescription only – consult your doctor.\n\n\nHigh-Ranking FAQs (Google Search & Voice Search Optimized)\n\n1. What is methylprednisolone sodium succinate injection used for?\nIt is used to rapidly control severe inflammation, allergic reactions, and autoimmune flare-ups, such as anaphylaxis, acute asthma attacks, and lupus or rheumatoid arthritis flares. It is administered under medical supervision in hospital or clinical settings.\n\n2. Is methylprednisolone injection a steroid?\nYes, it is a synthetic corticosteroid (glucocorticoid) that works by suppressing inflammatory and immune responses in the body, providing rapid relief in acute, severe conditions.\n\n3. How is methylprednisolone sodium succinate injection given?\nIt is given by a healthcare professional via intravenous (IV) or intramuscular (IM) injection, after being reconstituted with the correct diluent immediately before administration. It is not for self-injection or home use.\n\n4. How fast does methylprednisolone injection start working?\nBecause it is water-soluble and given directly into the bloodstream or muscle, measurable anti-inflammatory effects typically begin within one to two hours of administration.\n\n5. What are the side effects of methylprednisolone injection?\nCommon effects include elevated blood sugar, fluid retention, mood changes, and increased infection risk. These are monitored by the administering healthcare team, and serious reactions are managed promptly in a clinical setting.\n\n6. Is methylprednisolone sodium succinate injection available without a prescription?\nNo. It is a Schedule H prescription-only medicine that must be administered by or under the direct supervision of a qualified healthcare professional.\n\n7. What is the difference between methylprednisolone and dexamethasone injection?\nBoth are injectable corticosteroids, but dexamethasone has a longer duration of action and higher relative potency, while methylprednisolone is often preferred for acute pulse therapy and shorter-acting systemic control. The choice depends on the clinical scenario and physician judgment.\n\n8. Can methylprednisolone injection be used in pregnancy?\nIt may be used in pregnancy only when clearly necessary and under strict medical supervision, as the treating physician will weigh the benefits against potential risks for the specific condition being treated.", "price": 47.0, "discountamount": 19.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2465, "imageuri": "https://productimages.withfloats.com/actual/6a460bfb9f5529389b8b15b8.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a460bfb9f5529389b8b15b8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-07-02T06:58:01.631Z", "updatedon": "2026-07-02T06:58:01.631Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//methylprednisolone-sodium-succinate-for-injection-usp/2465", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "METHIDENOSOLE 40 INJ", "category": "GENERAL RANGE", "tags": [ "methylprednisolone sodium succinate injection uses", "methylprednisolone sodium succinate injection uses in hindi", "methylprednisolone sodium succinate", "methylprednisolone sodium succinate injection", "inj methylprednisolone sodium succinate", "methylprednisolone sodium succinate uses in hindi", "methylprednisolone sodium succinate for injection", "methylprednisolone sodium succinate injection usp" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }