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"description": "CARDULES ISMN SR 60 delivers Isosorbide Mononitrate IP 60mg in a sustained-release tablet form, designed for long-term prevention of angina in patients with coronary artery disease. Produced by Steris Healthcare Pvt Ltd, this formulation ensures steady drug release over 12-24 hours, optimizing cardiovascular protection with once-daily dosing convenience. It supports heart health by enhancing blood flow without the peaks and troughs of immediate-release options.\n\nProduct Overview\nCARDULES ISMN SR 60 contains Isosorbide Mononitrate IP 60mg per sustained-release tablet, a pure nitrate metabolite that bypasses first-pass liver metabolism for consistent bioavailability. The SR technology employs a polymer matrix to gradually liberate the active ingredient, maintaining therapeutic plasma levels throughout the day and minimizing tolerance development associated with frequent dosing. Available in strips of 10 tablets, it features a film-coated exterior for easy swallowing and gastro-resistant properties to protect against stomach acid degradation.\n\nThis higher 60mg strength suits patients requiring intensified prophylaxis after initial titration from lower doses like 30mg or 40mg. It integrates seamlessly into comprehensive cardiac regimens alongside beta-blockers, statins, or aspirin, under cardiologist supervision. Quality manufacturing adheres to IP standards, ensuring purity above 99% with low impurity profiles for safety in chronic use.\n\nKey Uses\nCARDULES ISMN SR 60 primarily prevents chronic stable angina pectoris by dilating coronary arteries and reducing myocardial oxygen demand during exertion. Patients experience fewer episodes of chest tightness, pressure, or discomfort triggered by physical activity, stress, or cold exposure.\n\nIt manages coronary artery disease (CAD) by improving collateral circulation and easing ischemia in narrowed vessels. Often prescribed post-angioplasty or alongside lifestyle modifications, it stabilizes symptoms for enhanced daily functioning.\n\nAdditionally, it supports adjunctive therapy in congestive heart failure or post-myocardial infarction recovery, where vasodilation unloads the heart. Not for acute attacks—use sublingual nitroglycerin instead—but vital for long-term risk reduction.\n\nMajor Benefits\nThe sustained-release profile of CARDULES ISMN SR 60 provides 24-hour angina prevention with single morning dosing, improving adherence over multiple-daily regimens. This steady vasodilation lowers preload via venous pooling and afterload via arterial relaxation, cutting oxygen consumption by up to 20-30% during stress.\n\nPatients report increased exercise tolerance, with treadmill tests showing delayed onset of ST-segment depression. Enhanced myocardial perfusion boosts energy levels, enabling return to work, hobbies, or family activities without fear of sudden symptoms.\n\nCompared to shorter-acting nitrates, tolerance buildup is slower due to a nitrate-free interval built into once-daily use. Cost-effective at higher strengths, it reduces overall healthcare visits and hospitalization risks from unstable angina.\n\nBenefit\tMechanism\tClinical Advantage\nAngina Prevention\tVasodilation reduces preload/afterload \tFewer episodes, better quality of life\nExercise Capacity\tImproved coronary flow \tExtended activity duration by 50%+\nDosing Simplicity\tSR once daily \t90% adherence rate vs. multiple doses\nHeart Protection\tLowers ischemia risk. \tReduced MI recurrence\nPotential Side Effects\nCommon effects include headache (orthostatic or throbbing), especially in the first week, resolving with hydration and dose acclimation—acetaminophen helps manage it. Dizziness, lightheadedness, or postural hypotension may occur; rise slowly from sitting.\n\nGastrointestinal upset like nausea or flushing affects 5-10% initially. Avoid alcohol or PDE5 inhibitors (e.g., sildenafil) to prevent severe hypotension.\n\nRarely, reflex tachycardia, rash, or methemoglobinemia arises; monitor liver enzymes in prolonged use. Contraindicated in severe anemia, glaucoma, or recent PDE5 intake—discontinue if allergic reactions appear.\n\nDosage Guidelines\nInitiate at 30-40mg daily, titrating to 60mg once in the morning on an empty stomach for optimal absorption. Swallow whole; do not crush. A 10-12 hour nitrate-free window (nighttime) prevents tolerance.\n\nAdjust for renal/hepatic impairment; max 120mg/day. Store below 25°C. Regular ECG and BP checks ensure efficacy.\nConclusion\nCARDULES ISMN SR 60 stands as a cornerstone in angina prophylaxis, empowering CAD patients with reliable, sustained vascular relief from Steris Healthcare. Consistent use alongside diet, exercise, and smoking cessation maximizes outcomes, but cardiologist oversight remains essential for safety",
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"description": "CARDULES ISMN SR 30 tablets provide sustained-release Isosorbide Mononitrate IP 30mg, a nitrate medication designed for long-term management of angina in patients with coronary artery disease. This formulation from Steris Healthcare Pvt Ltd ensures steady vasodilation to improve heart blood flow and reduce chest pain episodes. It supports daily activities by minimizing oxygen demand on the heart muscle.\nProduct Overview\nCARDULES ISMN SR 30 contains Isosorbide Mononitrate IP 30mg in a sustained-release matrix, allowing once-daily dosing for consistent therapeutic levels over 12-24 hours. The tablet's extended-release technology prevents peak-trough fluctuations common in immediate-release forms, promoting better patient compliance. Each film-coated tablet delivers precise bioavailability, with the active metabolite nitric oxide activating guanylate cyclase to boost cyclic GMP, relaxing vascular smooth muscle primarily in veins.\n\nThis mechanism reduces preload (venous return to the heart) and afterload (arterial resistance), easing cardiac workload without significantly affecting heart rate. Unlike short-acting nitrates for acute relief, CARDULES ISMN SR 30 targets prophylaxis in chronic stable angina, often prescribed alongside beta-blockers or calcium channel blockers. Available in strips of 10 tablets, it undergoes rigorous quality testing at Steris facilities to meet IP standards, ensuring purity and stability.\n\nKey Uses\nCARDULES ISMN SR 30 primarily prevents angina pectoris in coronary artery disease, where narrowed vessels limit oxygen supply during exertion. Patients experience fewer chest pain attacks during walking, climbing stairs, or stress.\n\nIt manages chronic stable angina by enhancing myocardial perfusion, suitable for long-term therapy in adults over 18. Healthcare providers may use it adjunctively for coronary spasm or post-myocardial infarction prophylaxis to stabilize symptoms.\n\nIn select cases, it aids heart failure management by offloading the heart, though not as monotherapy. Always initiate under cardiology supervision with dose titration to tolerance.\n\nMajor Benefits\nThe sustained-release profile offers 24-hour protection with single morning dosing, improving adherence and lifestyle quality for active patients. It boosts exercise tolerance by 20-30% in trials, allowing longer physical efforts without angina onset.\n\nBy dilating vessels, it decreases ischemia risk, potentially lowering hospitalization rates for acute episodes. Compared to placebo, users report halved attack frequency within weeks, enhancing daily productivity and emotional well-being.\n\nBenefit\tMechanism\tPatient Outcome\nAngina Prevention\tVasodilation reduces preload/afterload \tFewer attacks, better exertion capacity\nSteady Relief\tSR formulation maintains levels \tOnce-daily convenience, no fluctuations\nHeart Protection\tImproves O2 delivery \tReduced ischemia, enhanced QoL\nCompliance Boost\tSimple regimen \tHigher adherence vs multiple doses\nAdditional perks include minimal impact on blood pressure in normotensives and compatibility with anti-anginals, making it versatile in combo therapy.\n\nPotential Side Effects\nCommon effects include headache (dose-related, often transient in first week), dizziness, or flushing due to vasodilation—hydrate and rise slowly to manage. Gastrointestinal upset like nausea occurs in 5-10% initially.\n\nOrthostatic hypotension risks fainting, especially early; avoid alcohol or other vasodilators. Rare serious issues encompass severe hypotension, tachycardia, or methemoglobinemia with overdose—monitor blood pressure regularly.\n\nAllergic reactions (rash, itching) or vision changes warrant discontinuation. Contraindicated in hypotension, glaucoma, or recent PDE5 inhibitor use; caution in anemia or hypothyroidism.\n\nDosage Guidelines\nStart with 30mg once daily upon waking, swallowed whole without crushing. Titrate to 60mg if tolerated after 3-7 days, max 120mg/day. Take on empty stomach for optimal absorption; avoid late dosing to prevent nocturnal headaches.\n\nAdjust for elderly or renal/hepatic impairment. Tolerance may develop—nitrate-free interval (evening) helps sustain efficacy. Store below 30°C.\nConclusion\nCARDULES ISMN SR 30 empowers angina patients with reliable, once-daily prevention, restoring confidence in routine activities under Steris Healthcare's quality assurance. Its targeted vasodilation balances efficacy and tolerability for sustained heart health",
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"description": "ALFUGEM T 5/10 is a uniquely formulated combination of Alfuzosin Hydrochloride ER and Tadalafil, created to manage two common male health concerns—benign prostatic hyperplasia (BPH) and erectile dysfunction (ED). This dual-benefit tablet not only helps relieve urinary symptoms caused by an enlarged prostate but also enhances sexual performance by improving blood flow to penile tissues.\n\nAlfuzosin, an alpha-1 adrenergic blocker, works by relaxing the smooth muscles of the prostate and bladder neck, allowing for easier urine flow. On the other hand, Tadalafil, a PDE5 inhibitor, relaxes blood vessels and supports better erections during sexual activity. Together, they offer a holistic treatment option for men dealing with both prostate-related urinary difficulties and sexual health concerns.\n\nUses of ALFUGEM T 5/10\n\nBenign Prostatic Hyperplasia (BPH): Eases urinary issues such as weak stream, frequent urination, incomplete bladder emptying, and difficulty initiating urination.\n\nErectile Dysfunction (ED): Improves erectile quality and sexual satisfaction.\n\nDual Therapy: Provides relief for men suffering from both BPH and ED, minimizing the need for multiple medications.\n\nEnhanced Quality of Life: Restores comfort, confidence, and overall wellness by improving both urinary and sexual functions.\n\nSide Effects of ALFUGEM T 5/10\n\nLike most medications, ALFUGEM T 5/10 may cause side effects, usually mild and temporary as the body adapts to treatment.\n\nCommon side effects include:\n\nHeadache\n\nDizziness or lightheadedness\n\nNasal congestion\n\nBack pain\n\nFlushing\n\nLess common but serious side effects:\n\nSudden low blood pressure (hypotension)\n\nSevere dizziness or fainting\n\nProlonged, painful erections (priapism – requires urgent care)\n\nVision or hearing disturbances\n\nAllergic reactions (rash, itching, facial/lip/throat swelling)\n\nPrecautions Before Use\n\nHeart Problems: Patients with recent heart attack, stroke, or serious heart disease should only use under strict medical advice.\n\nBlood Pressure: May lower blood pressure—avoid combining with other strong antihypertensives unless prescribed.\n\nNitrate Warning: Must not be used with nitrate medications (for chest pain/angina) due to risk of severe hypotension.\n\nLiver or Kidney Impairment: Dose adjustments may be needed.\n\nAlertness: Can cause dizziness—avoid driving or operating heavy machinery until you know your body’s response.\n\nDrug Interactions\n\nALFUGEM T 5/10 may interact with other medicines:\n\nNitrates (Nitroglycerin, Isosorbide): Can lead to life-threatening hypotension.\n\nAntihypertensives: May intensify blood pressure-lowering effects.\n\nOther PDE5 inhibitors (Sildenafil, Vardenafil): Should not be combined.\n\nStrong CYP3A4 inhibitors (e.g., Ketoconazole, Ritonavir): May increase Alfuzosin or Tadalafil levels.\n\nAlcohol: Increases dizziness and risk of low blood pressure.\n\nConclusion\n\nALFUGEM T 5/10 (Alfuzosin Hydrochloride ER & Tadalafil Tablets) is a comprehensive dual-action therapy designed for men experiencing both urinary issues due to BPH and sexual challenges related to ED. By combining an effective alpha-blocker with a proven PDE5 inhibitor, it provides relief from urinary discomfort while restoring erectile performance and confidence.\n\nWith proper medical guidance, ALFUGEM T 5/10 can greatly improve overall quality of life, making it a reliable option for men seeking urological and sexual wellness in a single solution.",
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"description": "CARDULES ISDN 5 is a prescription medication formulated with Isosorbide Dinitrate (5 mg), a well-known nitrate used to prevent and treat chest pain (angina) caused by coronary artery disease. This medicine is commonly prescribed to improve blood flow to the heart and reduce the frequency and severity of anginal attacks. It works by relaxing the blood vessels, making it easier for the heart to pump blood, and reducing its oxygen demand. CARDULES ISDN 5 is especially useful for long-term management of chronic angina and can be an essential part of a comprehensive cardiac care plan.\n\nKey Ingredients\nIsosorbide Dinitrate (5 mg) – This is the active pharmaceutical ingredient in CARDULES ISDN 5. Belonging to the nitrate class of drugs, Isosorbide Dinitrate helps widen and relax blood vessels, thereby improving blood flow and oxygen delivery to the heart muscle.\n\nKey Benefits\nProvides effective relief from angina (chest pain)\n\nHelps prevent angina episodes when taken regularly\n\nImproves blood circulation to the heart\n\nReduces the heart's workload and oxygen demand\n\nSupports overall cardiac function in patients with coronary artery disease\n\nCan improve exercise tolerance and reduce anginal frequency\n\nHow Does It Work?\nCARDULES ISDN 5 works by releasing nitric oxide within the vascular smooth muscle, leading to the relaxation of blood vessels. This vasodilation effect reduces the amount of work the heart must do to pump blood and lowers its oxygen demand. By widening the arteries and veins, Isosorbide Dinitrate facilitates better oxygen delivery to the heart tissue, which helps prevent angina attacks. It is especially effective in preventing episodes when used on a regular schedule, rather than providing immediate relief during an ongoing attack.\n\nDirections for Use\nAlways take CARDULES ISDN 5 exactly as prescribed by your physician.\n\nTypically taken orally, with or without food.\n\nIt is important to take the medication at the same times each day to maintain consistent nitrate levels in the bloodstream.\n\nSwallow the tablet whole with water; do not crush or chew unless advised.\n\nDo not stop the medication abruptly without consulting your doctor, as it may worsen angina symptoms.\n\nSide Effects\nWhile CARDULES ISDN 5 is generally well-tolerated, some individuals may experience side effects. These can include:\n\nHeadache (commonly occurs initially and often subsides with continued use)\n\nDizziness or light-headedness, especially when rising from a sitting or lying position\n\nNausea or vomiting\n\nFlushing or warmth of the skin\n\nLow blood pressure (hypotension)\n\nRapid heartbeat (tachycardia)\n\nIn rare cases, allergic reactions or more serious cardiovascular effects may occur. Always report any persistent or severe side effects to your healthcare provider immediately.\n\n",
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"description": "Bisoprolol 5mg\nBISOPROLIN 5 is a highly effective medication containing Bisoprolol 5mg, a beta-blocker that is widely used to manage various cardiovascular conditions. Bisoprolol is a selective beta-1 adrenergic receptor blocker, which helps in reducing heart rate, blood pressure, and the overall workload on the heart. It is commonly prescribed to treat conditions like hypertension (high blood pressure), chronic heart failure, and angina (chest pain). BISOPROLIN 5 is an essential component of heart disease management, designed to improve heart function, reduce symptoms, and prevent further complications.\n\nKey Uses of BISOPROLIN 5\n1. Management of Hypertension (High Blood Pressure)\nBISOPROLIN 5 is frequently prescribed for hypertension, as it effectively lowers high blood pressure, helping to reduce the risk of life-threatening complications such as heart attacks, strokes, and kidney damage. By blocking beta-1 receptors in the heart, it helps in lowering heart rate and blood pressure.\n\n2. Treatment of Chronic Heart Failure (CHF)\nChronic heart failure is a condition where the heart's ability to pump blood is impaired. BISOPROLIN 5 is commonly used to improve heart function and reduce symptoms of heart failure such as shortness of breath, swelling in the legs, and fatigue. By lowering the workload on the heart, it helps manage heart failure symptoms and prevent hospitalizations.\n\n3. Prevention of Angina (Chest Pain)\nBISOPROLIN 5 helps in managing angina by reducing the heart's oxygen demand, thus preventing episodes of chest pain caused by insufficient blood flow to the heart. It is especially beneficial in patients with stable angina or other ischemic heart conditions.\n\n4. Management of Cardiac Arrhythmias\nBISOPROLIN 5 is effective in managing cardiac arrhythmias (irregular heartbeats), particularly atrial fibrillation. 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Reduced Risk of Cardiovascular Events\nBy lowering both blood pressure and heart rate, BISOPROLIN 5 helps reduce the risk of severe cardiovascular events like heart attacks and strokes.\n\nHow BISOPROLIN 5 Works\nBISOPROLIN 5 contains Bisoprolol, a beta-blocker that primarily affects the heart's beta-1 receptors. By binding to these receptors, Bisoprolol reduces the heart rate and the force of heart contractions. This helps the heart beat more efficiently and requires less oxygen, especially during periods of stress or activity. Additionally, Bisoprolol dilates blood vessels, leading to lower blood pressure.\n\nBy reducing the heart's workload, BISOPROLIN 5 not only manages hypertension and heart failure symptoms but also decreases the risk of arrhythmias and angina.\n\nDosage and Administration\nRecommended Dosage\nThe usual dose of BISOPROLIN 5 is 5mg once daily. 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Common side effects include:\n\nCommon Side Effects\nFatigue or Tiredness: Feeling excessively tired is a common side effect, especially in the initial stages of treatment.\nDizziness or Lightheadedness: This can occur, particularly when standing up quickly.\nSlow Heart Rate (Bradycardia): A reduced heart rate is a common effect of Bisoprolol.\nCold Extremities: Hands and feet may feel cold due to reduced blood flow.\nNausea or Upset Stomach: Mild stomach discomfort may be experienced.\nRare but Serious Side Effects\nSevere Bradycardia (Extremely Slow Heart Rate): If the heart rate drops too much, it may lead to fainting or severe dizziness.\nBreathing Problems: Difficulty breathing or wheezing, especially in individuals with asthma.\nSevere Allergic Reactions: Such as swelling of the face, lips, or throat.\nLiver Dysfunction: Signs of liver problems include jaundice, dark urine, or persistent nausea.\nIf any severe or persistent side effects occur, contact your healthcare provider immediately.\n\nDrug Interactions\nBISOPROLIN 5 may interact with certain medications, affecting its effectiveness or increasing the risk of side effects. Some common drug interactions include:\n\nOther Blood Pressure-Lowering Drugs: Combining BISOPROLIN 5 with other antihypertensive medications (e.g., calcium channel blockers or ACE inhibitors) may lead to excessively low blood pressure.\nAnti-arrhythmic Drugs: Medications for heart rhythm disorders, such as amiodarone or sotalol, may interact with Bisoprolol.\nInsulin or Oral Diabetes Medications: Bisoprolol can mask the symptoms of low blood sugar (hypoglycemia), so extra monitoring is needed in diabetic patients.\nNSAIDs (Non-Steroidal Anti-Inflammatory Drugs): These may reduce the blood pressure-lowering effect of BISOPROLIN 5.\nAntidepressants or Antipsychotics: Certain psychiatric medications may enhance Bisoprolol’s side effects, such as dizziness and fatigue.\nAlways inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are currently taking.\n\nPrecautions and Warnings\n1. Who Should Avoid BISOPROLIN 5?\nPeople with severe asthma, COPD (Chronic Obstructive Pulmonary Disease), or other respiratory disorders.\nIndividuals with a history of heart block or very low heart rate (bradycardia).\nThose with uncontrolled heart failure or shock.\n2. Pregnancy and Breastfeeding\nBISOPROLIN 5 should only be used during pregnancy if absolutely necessary. It is not recommended for breastfeeding mothers, as it may pass into breast milk.\n\n3. Regular Monitoring\nIt is important to regularly monitor blood pressure and heart rate while taking BISOPROLIN 5. 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Atenolol is particularly effective in treating high blood pressure and preventing heart attacks.\nKey Benefits\nReduces High Blood Pressure: The combination of Amlodipine and Atenolol helps to lower high blood pressure, reducing the risk of heart disease, stroke, and kidney problems.\nPrevents Angina: This medication helps alleviate chest pain caused by reduced blood flow to the heart, improving overall heart function and reducing the frequency of angina episodes.\nImproves Heart Function: By controlling both blood pressure and heart rate, Amdules AT helps your heart work more efficiently, especially in conditions like hypertension and coronary artery disease.\nReduces the Risk of Heart Attack: The medication helps reduce the risk of heart attack by controlling high blood pressure and reducing the strain on the heart.\nConvenient Dual Therapy: With both Amlodipine and Atenolol in one tablet, this product simplifies treatment, eliminating the need to take two separate medications.\nHow Does It Work?\nAmlodipine works by blocking the entry of calcium into heart and blood vessel cells, which prevents the contraction of blood vessels and allows them to dilate. This leads to a decrease in blood pressure and a reduction in the heart's workload. Amlodipine also helps improve blood flow to the heart, alleviating symptoms of angina.\n\nAtenolol, on the other hand, works by blocking the beta-receptors in the heart, which decreases the heart rate and the force of the heart’s contractions. This leads to lower blood pressure and reduced oxygen demand for the heart, helping to prevent complications related to hypertension and heart disease.\n\nTogether, these two ingredients work synergistically to reduce blood pressure, prevent chest pain, and improve overall heart health.\n\nDirections for Use\nDosage: The dosage of Amdules AT will be determined by your healthcare provider based on your individual needs and condition.\nAdministration: Take the tablet as prescribed, usually once a day, with or without food. Swallow the tablet whole with a glass of water. 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"description": "AMdules 2.5, containing Amlodipine (2.5mg), is a trusted solution for managing high blood pressure and certain heart conditions. This prescription medication belongs to the calcium channel blocker class and works effectively to relax blood vessels, improve blood flow, and reduce the workload on the heart. Designed for precision in dosage and effectiveness, AMdules 2.5 helps patients achieve better cardiovascular health while minimizing risks associated with hypertension and angina.\n\n \nKey Benefits:\n \n\nBlood Pressure Management: Effectively lowers high blood pressure (hypertension), reducing strain on the heart and blood vessels.\nAngina Relief: Helps alleviate chest pain caused by reduced blood flow to the heart.\nImproved Blood Flow: Promotes smoother blood circulation by relaxing blood vessels.\nHeart Health: Reduces the risk of cardiovascular complications, including heart attack and stroke.\nWell-Tolerated Dosage: The 2.5mg dose is ideal for patients requiring mild yet effective intervention.\n\nHow Does It Work?\n\nAMdules 2.5 works by inhibiting calcium ions from entering the smooth muscle cells of the heart and blood vessels. This action relaxes and widens the blood vessels, leading to:\n\nLower blood pressure: Reducing the heart's workload.\nIncreased oxygen delivery: Improving blood flow to the heart and relieving chest pain in angina patients.\nThis dual action ensures effective control over hypertension and angina symptoms, supporting long-term cardiovascular health.\n \nDirections for Use:\n\nDosage: Take AMdules 2.5 exactly as prescribed by your healthcare provider.\nAdministration: Swallow the tablet with water, preferably at the same time each day.\nWith or Without Food: It can be taken with or without meals.\nAvoid Abrupt Discontinuation: Do not stop taking the medication without consulting your doctor, as this may worsen your condition.\n \nSide Effects:\n \nWhile AMdules 2.5 is generally well-tolerated, some individuals may experience mild side effects such as:\n\nDizziness or lightheadedness\nSwelling in the ankles or feet (edema)\nFatigue\nHeadache\nNausea\nIf side effects persist or become severe, consult your healthcare provider immediately.",
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