Home> Products> angina patients

{ "products": [ { "_id": "69e9f8f5051af90911258c1b", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "nebivolol 5mg cilnidipine 10mg", "description": "Nebivolol 5mg + Cilnidipine 10mg Tablets—Complete Guide\nA fixed-dose combination antihypertensive for effective blood pressure control. Understand how it works, who it's for, dosage, and safety before you buy.\n\nDrug Class\nBeta-blocker + Calcium Channel Blocker\nStrength\nNebivolol 5mg / Cilnidipine 10mg\nRoute\nOral (tablet)\nSchedule\nRx Only\nWhat is this combination?\nUnderstanding nebivolol 5mg + cilnidipine 10mg\nNebivolol 5mg + cilnidipine 10mg is a fixed-dose combination tablet prescribed for the management of hypertension (high blood pressure) in adults. It pairs two complementary mechanisms into one convenient pill, making it a popular choice when single-drug therapy proves insufficient for adequate blood pressure control.\n\nThis combination is widely preferred by cardiologists when patients need better BP reduction with fewer pills, improved tolerability, and protection of vital organs such as the heart and kidneys. If your doctor has prescribed this tablet, you're likely being treated for stage 1 or stage 2 hypertension, with or without associated cardiovascular risk factors.\n\nThis is not an over-the-counter product. Always use nebivolol + cilnidipine tablets only under the supervision of a licensed physician. Self-medication or dose changes without medical advice can be dangerous.\nHow it works\nMechanism of action — dual-pathway blood pressure control\nThe effectiveness of this combination lies in how its two active ingredients target blood pressure through different pathways simultaneously:\n\nNebivolol 5mg\nA third-generation cardioselective beta-1 blocker. It slows the heart rate, reduces the force of cardiac contraction, and lowers cardiac output. Uniquely, nebivolol also releases nitric oxide, causing blood vessel relaxation — a property not seen in older beta-blockers. This makes it better tolerated and less likely to cause sexual dysfunction or cold extremities.\nCilnidipine 10mg\nAn N/L-type calcium channel blocker. Unlike conventional CCBs (e.g., amlodipine), cilnidipine blocks both L-type and N-type calcium channels. N-type blockade in the sympathetic nervous system reduces norepinephrine release, leading to smoother, more sustained BP reduction with significantly less ankle swelling — a common complaint with older CCBs.\nTogether, these agents provide additive antihypertensive effect while offsetting each other's side effects. Nebivolol reduces tachycardia that CCBs can sometimes cause, while cilnidipine's vasodilatory effect complements nebivolol's cardiac output reduction.\n\nIndications\nWho is Nebivolol 5 mg and Cilnidipine 10 mg prescribed for?\nThis combination is indicated for adults with hypertension who are not adequately controlled on monotherapy. It is especially suited for patients who have:\n\nCondition:\tWhy this combination is preferred\nHypertension with high heart rate\tNebivolol slows heart rate while cilnidipine controls peripheral resistance\nHypertension with diabetes\tMetabolically neutral; does not worsen glucose tolerance or lipid profile\nHypertension with CKD / proteinuria:\tCilnidipine's N-type blockade reduces glomerular pressure and protein leakage\nHypertension with coronary artery disease\tNebivolol provides cardioprotection and anti-anginal effect\nAmlodipine-related ankle edema\tSwitching to cilnidipine substantially reduces pedal edema due to N-type blockade\nUncontrolled BP on single antihypertensive\tCombination adds complementary mechanisms without increasing pill burden\n\nosage & Administration\nHow to take nebivolol 5 mg + cilnidipine 10mg\nThe standard recommended dose is one tablet once daily, preferably at the same time each day — most commonly in the morning with or without food. Your physician may adjust the dose based on your blood pressure response and individual tolerability.\n\nDo not crush, chew, or split the tablet unless your doctor advises. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose. Never double up on doses. Swallowing the tablet whole with water is the preferred method of administration.\n\nDo not stop taking this medication abruptly. Sudden discontinuation of nebivolol (a beta-blocker) can trigger rebound hypertension or even angina in patients with underlying coronary disease. Always taper under medical guidance.\n\nCommon and serious side effects to know\nLike all medicines, nebivolol + cilnidipine can cause side effects, though not everyone experiences them. Knowing what to watch for helps you respond promptly.\n\nSide effect\tFrequency\tWhat to do\nHeadache, dizziness\tCommon (early phase)\tUsually resolves in 1–2 weeks; avoid sudden posture changes\nFatigue, tiredness\tCommon\tMonitor; often improves after dose adjustment\nAnkle swelling (pedal edema)\tLess common than with amlodipine\tReport if worsening; may require dose review\nBradycardia (slow heart rate)\tUncommon\tSeek medical advice if heart rate <50 bpm\nNausea, stomach upset\tUncommon\tTake after meals to minimise\nBronchospasm\tRare\tStop immediately; seek emergency care if breathlessness\nSevere hypotension\tRare\tEmergency — seek immediate medical attention.\n\nWhen should this combination not be used?\nImportant safety information\nThis tablet is contraindicated in: cardiogenic shock, decompensated heart failure, severe bradycardia (<60 bpm), sick sinus syndrome, second- or third-degree AV block (without pacemaker), severe hepatic impairment, known hypersensitivity to nebivolol or cilnidipine, pregnancy, and breastfeeding.\n\nUse with caution in patients with asthma or COPD (nebivolol has some beta-2 activity at higher doses), peripheral vascular disease, diabetes mellitus (may mask hypoglycemic symptoms), and in elderly patients prone to falls due to postural hypotension.\n\nAlways inform your doctor of all medications you are currently taking. Clinically significant interactions exist with other antihypertensives, NSAIDs, digoxin, antidiabetic agents, and CYP2D6 inhibitors (e.g., fluoxetine, paroxetine), which can raise nebivolol plasma levels.\n\n\n\n\n", "price": 305.0, "discountamount": 91.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2389, "imageuri": "https://productimages.withfloats.com/actual/69e9f8f745652456a0f3a497.png", "tileimageuri": "https://productimages.withfloats.com/tile/69e9f8f745652456a0f3a497.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-04-23T10:48:21.085Z", "updatedon": "2026-04-29T05:46:26.285Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/nebivolol-5mg-cilnidipine-10mg/2389", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "NEBIVALVE CILNL 5/10", "category": "CARDIOLOGYRANGE", "tags": [ "nebivolol 5mg cilnidipine 10mg", "What is nebivolol 5mg and cilnidipine 10 mg used for?", "nebivolol cilnidipine", "nebivolol cilnidipine tab", "nebivolol cilnidipine uses", "nebivolol 5mg cilnidipine 10mg price", "nebivolol 5mg cilnidipine 10mg price in india", "nebivolol cilnidipine", "nebivolol 5mg cilnidipine 10mg" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69c5151e8b3087f0806a6258", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Trimetazidine Dihydrochloride Tablets 20 mg", "description": "TRIMETAZ 20 is a clinically proven medication formulated with Trimetazidine Dihydrochloride 20 mg. It is primarily used in the management of angina pectoris, a condition caused by reduced blood flow to the heart muscles. Unlike conventional heart medications that directly affect heart rate or blood pressure, TRIMETAZ 20 works at the cellular level to improve energy metabolism in heart cells.\n\nHeart-related conditions are becoming increasingly common due to sedentary lifestyles, stress, and unhealthy dietary habits. TRIMETAZ 20 provides an effective solution by protecting heart cells from damage caused by oxygen deficiency, helping patients maintain better cardiovascular health.\nHow TRIMETAZ 20 Works\nTRIMETAZ 20 works by optimizing the energy processes within heart cells. It shifts the heart’s energy metabolism from fatty acid oxidation to glucose oxidation, which requires less oxygen to produce energy.\n\nThis mechanism helps:\n\nImprove efficiency of heart cells during low oxygen supply\nReduce damage caused by ischemia (restricted blood flow)\nMaintain proper functioning of cardiac cells\n\nBy enhancing energy utilization, TRIMETAZ 20 allows the heart to function more effectively even under stress conditions, reducing symptoms of angina.\n\nUses of TRIMETAZ 20\n1. Management of Angina Pectoris\n\nTRIMETAZ 20 is widely used as an adjunct therapy in patients suffering from angina. It helps reduce chest pain episodes and improves exercise tolerance.\n\n2. Support in Ischemic Heart Disease\n\nIt is beneficial for patients with ischemic conditions where the heart does not receive adequate oxygen supply.\n\n3. Improvement in Cardiac Efficiency\n\nTRIMETAZ 20 enhances the overall efficiency of heart muscles, making it easier for patients to carry out daily activities without discomfort.\n\n4. Adjunct Therapy in Cardiovascular Treatment\n\nIt is often prescribed alongside other heart medications to provide comprehensive cardiac care.\n\nKey Benefits of TRIMETAZ 20\n1. Reduces Frequency of Angina Attacks\n\nRegular use helps decrease the number and severity of chest pain episodes, improving patient comfort.\n\n2. Improves Exercise Tolerance\n\nPatients can perform physical activities with less fatigue and discomfort due to improved cardiac efficiency.\n\n3. Protects Heart Cells\n\nTRIMETAZ 20 prevents damage to heart cells caused by lack of oxygen, ensuring long-term cardiac health.\n\n4. Does Not Affect Blood Pressure or Heart Rate\n\nUnlike many heart medications, it works without significantly altering heart rate or blood pressure, making it suitable for a wide range of patients.\n\n5. Enhances Quality of Life\n\nBy reducing symptoms and improving stamina, it allows patients to lead a more active and normal life.\n\n6. Supports Long-Term Heart Health\n\nContinuous use under medical supervision can help maintain stable heart function over time.\n\nDosage and Administration\n\nTRIMETAZ 20 should be taken strictly as prescribed by a healthcare professional.\n\nUsually taken 2–3 times daily with meals\nSwallow the tablet whole with water\nDo not crush or chew the tablet\nMaintain consistent timing for best results\n\nDo not stop the medication abruptly without consulting your doctor, as it may worsen symptoms.\n\nPossible Side Effects of TRIMETAZ 20\n\nWhile TRIMETAZ 20 is generally well-tolerated, some patients may experience mild to moderate side effects.\n\nCommon Side Effects\nNausea\nDizziness\nHeadache\nAbdominal discomfort\nLess Common Side Effects\nWeakness or fatigue\nSkin rash\nVomiting\nRare but Serious Side Effects\nMovement disorders (such as tremors or rigidity)\nDifficulty in walking\nSevere allergic reactions\n\nIf any serious symptoms occur, immediate medical attention is required.\n\nPrecautions and Warnings\nNot recommended for patients with Parkinsonian disorders or movement-related conditions\nUse cautiously in elderly patients\nPatients with kidney problems should consult a doctor before use\nAvoid alcohol consumption while taking this medication\nNot advised during pregnancy or breastfeeding unless prescribed\nDrug Interactions\n\nTRIMETAZ 20 may interact with other medications, including:\n\nAntihypertensive drugs\nAntiplatelet medications\nOther cardiovascular drugs\n\nAlways inform your doctor about all medications and supplements you are taking.\n\nStorage Instructions\nStore in a cool and dry place\nKeep away from direct sunlight\nKeep out of reach of children\nConclusion\nTRIMETAZ 20 (Trimetazidine Dihydrochloride Tablets 20 mg) is an effective and reliable medication for managing angina and improving heart health. Its unique mechanism of action focuses on enhancing cellular energy metabolism, making it different from traditional heart drugs.", "price": 84.0, "discountamount": 25.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2355, "imageuri": "https://productimages.withfloats.com/actual/69c51520ca3a59786047fdbc.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/69c51520ca3a59786047fdbc.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-03-26T11:14:38.255Z", "updatedon": "2026-03-26T11:14:38.255Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//trimetazidine-dihydrochloride-tablets-20-mg/2355", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "TRIMETAZ 20", "category": "CARDIOLOGYRANGE", "tags": [ "trimetazidine dihydrochloride tablets 20 mg uses", "trimetazidine 20 mg tablets for chest pain" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "698aed05bd17d506b6a94192", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Diltiazem Hydrochloride Tablets 90 mg", "description": "DILTITAB SR 90 is a sustained-release formulation of Diltiazem Hydrochloride Tablets 90 mg, widely prescribed for the management of cardiovascular conditions such as hypertension, angina pectoris, and certain heart rhythm disorders. Designed for controlled drug release, DILTITAB SR 90 ensures prolonged therapeutic action with improved patient compliance and consistent blood pressure control throughout the day.\n\nDiltiazem belongs to the class of medications known as calcium channel blockers, which work by relaxing blood vessels and improving blood flow to the heart. With its sustained-release technology, DILTITAB SR 90 offers effective symptom relief while minimizing fluctuations in drug levels.\n\nProduct Description\n\nDILTITAB SR 90 contains Diltiazem Hydrochloride 90 mg in a sustained-release tablet form. This formulation allows the medication to be released slowly into the bloodstream, maintaining stable drug concentrations over an extended period. As a result, patients benefit from better symptom control and reduced dosing frequency compared to immediate-release tablets.\n\nDiltiazem plays a crucial role in managing cardiovascular stress by reducing the workload on the heart. By improving oxygen supply to the heart muscle and lowering blood pressure, DILTITAB SR 90 supports long-term heart health and enhances overall quality of life for patients with chronic cardiac conditions.\n\nUses of DILTITAB SR 90\n\nDILTITAB SR 90 is primarily prescribed for the following medical conditions:\n\n1. Hypertension (High Blood Pressure)\n\nDILTITAB SR 90 helps lower blood pressure by relaxing and widening blood vessels. This reduces resistance to blood flow, allowing the heart to pump blood more efficiently and decreasing the risk of complications such as stroke, heart attack, and kidney damage.\n\n2. Angina Pectoris (Chest Pain)\n\nAngina occurs when the heart muscle does not receive enough oxygen-rich blood. Diltiazem improves blood flow to the heart, reduces heart workload, and helps prevent episodes of chest pain during physical or emotional stress.\n3. Certain Heart Rhythm Disorders\nDILTITAB SR 90 may be used in the management of supraventricular arrhythmias, where it helps regulate heart rate by slowing electrical conduction through the heart’s atrioventricular node.\n\nHow DILTITAB SR 90 Works\n\nDiltiazem hydrochloride works by blocking calcium channels in the heart and blood vessel walls. Calcium plays a vital role in muscle contraction, including the contraction of the heart and blood vessels. By limiting calcium entry:\nBlood vessels relax and widen\nHeart rate may slow down\nOxygen demand of the heart is reduced\n\nThe sustained-release (SR) formulation in DILTITAB SR 90 ensures a gradual release of medication, providing long-lasting effects and maintaining steady blood pressure and heart rate control.\n\nKey Benefits of DILTITAB SR 90\n1. Long-Lasting Blood Pressure Control\nThe sustained-release design provides consistent blood pressure management throughout the day, reducing sudden spikes or drops.\n2. Improved Heart Efficiency\nBy lowering heart workload and improving blood flow, DILTITAB SR 90 helps the heart function more efficiently.\n3. Reduced Frequency of Angina Attacks\nRegular use decreases the frequency and severity of chest pain episodes, improving exercise tolerance.\n\n4. Better Patient Compliance\nOnce-daily or reduced-frequency dosing improves adherence compared to short-acting formulations.\n5. Stable Drug Levels\nMinimizes fluctuations in blood concentration, leading to fewer side effects and more predictable therapeutic outcomes.\n\nSide Effects of DILTITAB SR 90\n\nLike all medications, DILTITAB SR 90 may cause side effects in some individuals. Most side effects are mild and temporary, especially during the initial phase of treatment.\n\nCommon Side Effects\n\nHeadache\n\nDizziness or light-headedness\n\nFatigue or weakness\n\nFlushing\n\nMild swelling of ankles or feet\n\nConstipation or nausea\n\nThese effects usually improve as the body adjusts to the medication.\n\nLess Common but Serious Side Effects\n\nSeek medical attention if you experience:\n\nIrregular or very slow heartbeat\n\nSevere dizziness or fainting\n\nShortness of breath\n\nUnusual swelling or rapid weight gain\n\nAllergic reactions such as rash, itching, or swelling of face and lips\n\nPrecautions and Safety Information\n\nTake DILTITAB SR 90 exactly as prescribed by your doctor.\n\nDo not crush or chew the tablet, as it may affect the sustained-release mechanism.\n\nInform your doctor if you have liver disease, kidney disease, heart failure, or low blood pressure.\n\nAvoid alcohol unless advised, as it may enhance dizziness.\n\nPregnant or breastfeeding women should use this medicine only after medical consultation.\n\nConclusion\n\nDILTITAB SR 90 (Diltiazem Hydrochloride Tablets 90 mg) is a reliable and effective medication for the long-term management of hypertension, angina, and certain heart rhythm disorders. Its sustained-release formulation ensures steady therapeutic action, better symptom control, and improved patient compliance.\nBy relaxing blood vessels, reducing heart workload, and enhancing blood flow, DILTITAB SR 90 plays a vital role in protecting cardiovascular health and improving daily functioning. When used as directed under medical supervision, it offers a safe and dependable solution for patients seeking consistent heart and blood pressure control.", "price": 168.0, "discountamount": 49.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2298, "imageuri": "https://productimages.withfloats.com/actual/698aed07901799b6296f1487.png", "tileimageuri": "https://productimages.withfloats.com/tile/698aed07901799b6296f1487.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-02-10T08:32:05.108Z", "updatedon": "2026-03-13T10:51:05.197Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//diltiazem-hydrochloride-tablets-90-mg/2298", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "DILTITAB SR 90", "category": "CARDIOLOGYRANGE", "tags": [ "Diltiazem Hydrochloride Tablets 90 mg", "what is diltiazem hydrochloride 90 mg used for", "how diltiazem 90 mg works", "diltiazem 90 mg tablet benefits", "diltiazem hydrochloride 90 mg for blood pressure", "is diltiazem hydrochloride 90 mg safe", "how long does diltiazem 90 mg take to work", "what are the side effects of diltiazem 90 mg", "can diltiazem 90 mg cause low heart rate", "iltiazem hydrochloride tablets 90 mg price", "diltiazem 90 mg tablet brand", "diltiazem hydrochloride 90 mg tablet cost", "diltiazem hydrochloride tablets 90 mg india", "diltiazem hydrochloride tablets manufacturer", "diltiazem 90 mg dosage for elderly patients", "diltiazem 90 mg tablet after meals or before" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "695902b02c7664595f5073c1", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Ivabradine 5mg", "description": "Introduction\n\nA healthy heart rhythm is essential for maintaining energy, stamina, and overall well-being. When the heart beats too fast at rest, it can place unnecessary strain on the heart muscle, reduce blood supply to vital organs, and increase the risk of long-term cardiovascular complications. Conditions such as chronic stable angina and certain types of heart failure are often associated with an elevated resting heart rate, which can worsen symptoms and limit daily activities.\n\nIVADRIVE 5, containing Ivabradine 5 mg, is a specialized heart-rate–lowering medication designed to help control heart rate without reducing blood pressure or weakening heart contraction. Unlike many traditional cardiac drugs, IVADRIVE 5 works selectively on the heart’s natural pacemaker, helping the heart beat more slowly and efficiently. This targeted approach allows patients to experience better symptom control, improved exercise tolerance, and enhanced quality of life.\n\nComposition\n\nActive Ingredient: Ivabradine 5 mg\n\nBrand Name: IVADRIVE 5\n\nDosage Form: Oral Tablet\n\nIvabradine belongs to a unique class of medications known as selective heart rate–reducing agents.\n\nHow IVADRIVE 5 Works\n\nThe heart’s rhythm is controlled by a natural pacemaker called the sinoatrial (SA) node. Ivabradine acts specifically on the “If” (funny) channels in the SA node, which are responsible for regulating heart rate.\n\nBy selectively inhibiting these channels:\n\nThe heart rate slows down\n\nOxygen demand of the heart is reduced\n\nBlood flow to the heart muscle improves\n\nCardiac efficiency increases\n\nImportantly, IVADRIVE 5 lowers heart rate without affecting blood pressure or heart muscle strength, making it especially suitable for patients who cannot tolerate beta-blockers or require additional heart rate control.\n\nUses of IVADRIVE 5\n1. Chronic Stable Angina\n\nIVADRIVE 5 is widely used to treat chronic stable angina in patients with normal heart rhythm but elevated resting heart rate. By slowing the heart rate, it reduces chest pain episodes and improves exercise tolerance.\n\n2. Chronic Heart Failure\n\nIt is prescribed in selected patients with chronic heart failure to reduce hospitalizations and improve heart function when heart rate remains high despite standard therapy.\n\n3. Heart Rate Control\n\nIVADRIVE 5 is beneficial for patients who require heart rate reduction but cannot tolerate traditional heart-rate-lowering drugs.\n\nKey Benefits of IVADRIVE 5\n1. Effective Heart Rate Reduction\n\nIVADRIVE 5 specifically lowers resting heart rate, helping the heart work more efficiently and reducing strain on the heart muscle.\n\n2. Improves Exercise Capacity\n\nPatients often notice improved stamina and reduced fatigue during physical activity due to better oxygen delivery.\n\n3. Reduces Angina Attacks\n\nBy decreasing oxygen demand, IVADRIVE 5 helps lower the frequency and severity of chest pain episodes.\n\n4. Preserves Blood Pressure\n\nUnlike many cardiac medicines, it does not significantly lower blood pressure, making it suitable for patients with normal or low blood pressure.\n\n5. Supports Long-Term Heart Health\n\nConsistent use may help reduce disease progression and hospitalization risk in heart failure patients.\n\n6. Well-Tolerated Option\n\nIVADRIVE 5 is generally well tolerated and can be used alone or in combination with other cardiovascular medications under medical supervision.\n\nDosage and Administration\n\nThe usual starting dose is Ivabradine 5 mg, taken twice daily.\n\nTablets should be taken with meals for optimal absorption.\n\nDose adjustments may be made based on heart rate response and tolerance.\n\nImportant: Always follow your doctor’s instructions and do not stop or change the dose without medical advice.\n\nPossible Side Effects of IVADRIVE 5\n\nWhile IVADRIVE 5 is generally safe when used as prescribed, some patients may experience side effects.\n\nCommon Side Effects\n\nSlow heart rate (bradycardia)\n\nHeadache\n\nDizziness\n\nFatigue\n\nVisual Disturbances\n\nTemporary brightness or light flashes (phosphenes)\n\nBlurred vision in low-light conditions\nThese effects are usually mild and reversible.\n\nLess Common Side Effects\n\nNausea\n\nLow blood pressure symptoms\n\nIrregular heartbeat sensations\n\nRare Side Effects\n\nSevere bradycardia\n\nHeart rhythm disturbances\n\nPatients should report any persistent or severe symptoms to their healthcare provider promptly.\n\nPrecautions and Warnings\n\nHeart Rhythm Disorders: Not recommended in patients with certain arrhythmias.\n\nLow Heart Rate: Should not be used if resting heart rate is already very low.\n\nPregnancy and Breastfeeding: Use only if clearly advised by a doctor.\n\nLiver Disorders: Caution is advised in patients with liver impairment.\n\nDrug Interactions: Inform your doctor about all medications, including antifungals, antibiotics, and herbal supplements.\n\nWho Should Avoid IVADRIVE 5?\n\nPatients with severe bradycardia\n\nIndividuals with acute heart failure\n\nPatients with pacemaker dependency\n\nThose allergic to Ivabradine\n\nStorage Instructions\n\nStore below 25°C\n\nProtect from moisture and direct sunlight\n\nKeep out of reach of children\n\nDo not use after expiry date\n\nConclusion\n\nIVADRIVE 5 (Ivabradine 5 mg) offers a focused and effective solution for managing elevated heart rate in patients with chronic stable angina and selected cases of heart failure. By selectively acting on the heart’s natural pacemaker, it delivers targeted heart rate control without compromising blood pressure or cardiac strength.", "price": 249.0, "discountamount": 75.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2265, "imageuri": "https://productimages.withfloats.com/actual/695902b52b74f370f37d0f73.jpeg", "tileimageuri": "https://productimages.withfloats.com/tile/695902b52b74f370f37d0f73.jpeg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-03T11:51:12.052Z", "updatedon": "2026-03-13T11:21:14.037Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//ivabradine-5mg/2265", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "IVADRIVE 5", "category": "CARDIOLOGYRANGE", "tags": [ "Ivabradine 5 mg", "blood pressure or cardiac strength.", "ivabradine 5mg tablet uses", "tab ivabradine 5mg", "t ivabradine 5mg", "ivabradine 5mg tab", "ivabradine 5mg uses", "ivabradine 5mg tablets", "ivabradine 5mg side effects", "tablet ivabradine 5mg", "ivabradine 5mg tablet", "ivabradine 5mg uses in hindi", "what is ivabradine 5mg used for", "ivabradine 5mg price", "price of ivabradine 5mg" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6958dbfa1063d98b1e8f2fe1", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Benidipine 4mg", "description": "BENIPRIME 4, containing Benidipine 4 mg, offers effective management for high blood pressure and related heart conditions. This calcium channel blocker helps relax blood vessels to improve blood flow and reduce strain on the heart. Patients often find it reliable for daily control of hypertension symptoms.\n\nWhat is BENIPRIME 4?\nBENIPRIME 4 is a branded tablet from Steris Healthcare Pvt Ltd, featuring 4 mg of Benidipine as the active ingredient. Benidipine belongs to the dihydropyridine class of calcium channel blockers, designed specifically for cardiovascular health. Each tablet delivers a precise dose in a user-friendly form, typically packaged in strips of 10 for convenient use. Manufactured under strict quality standards, it targets essential needs in hypertension care, making it a staple in many treatment plans across India.\n​\n\nThis medication stands out due to its triple action on L-type, N-type, and T-type calcium channels, providing broader vascular protection compared to some other blockers. Doctors prescribe it for adults dealing with persistent high blood pressure or chest pain, often starting at this 4 mg strength for balanced efficacy. Unlike generic options, BENIPRIME 4 ensures consistent absorption and formulation tailored for Indian patients, with pricing around Rs 62-89 per strip after discounts.\n​\n\nHow BENIPRIME 4 Works\nBenidipine in BENIPRIME 4 blocks calcium entry into smooth muscle cells of blood vessels and heart muscles. This action causes vasodilation, widening arteries to lower resistance and ease blood flow. By reducing systolic and diastolic pressure, it lightens the heart's workload without drastically slowing the heartbeat.\n​\n\nThe unique blockade of multiple calcium channels also boosts nitric oxide production, offering antioxidant effects and protection against artery hardening. This sustained mechanism provides 24-hour control, ideal for once-daily dosing after breakfast. Over time, it may even reduce urinary protein and triglycerides, supporting kidney and metabolic health in hypertensives.\n​\n\nKey Uses of BENIPRIME 4\nBENIPRIME 4 primarily treats essential hypertension, helping prevent strokes, heart attacks, and kidney damage. It effectively manages angina pectoris by enhancing coronary blood supply, reducing chest pain episodes during activity.\n​\n\nPhysicians also use it for renal parenchymal hypertension, where kidney issues elevate blood pressure. In emergencies like hypertensive crises or subarachnoid hemorrhage, higher doses prove beneficial, though 4mg serves as maintenance. For arrhythmia or anal fissures linked to vascular strain, it offers supportive relief.\n​\n\nLowers high blood pressure in adults, including severe cases with dose adjustments.\n​\n\nEases angina symptoms, improving exercise tolerance and daily life quality.\n​\n\nProtects renal function in proteinuric patients by stabilizing vessels.\n​\n\nDosage and Administration\nTake BENIPRIME 4 as 4 mg once daily, swallowed whole after a meal to minimize stomach upset. Doctors may adjust to 2-8mg based on response, age, or kidney/liver status, never exceeding 8 mg daily without monitoring. Consistency in timing ensures steady levels for optimal pressure control.\n​\n\nMissed doses require prompt intake if remembered soon, but skip if near the next one—avoid doubles. Pair with lifestyle changes like low-salt diets and exercise for best results. Always consult for personalization, especially in elderly or comorbid patients.\n​\n\nKey Benefits\nBENIPRIME 4 excels in long-term blood pressure reduction, with studies showing sustained drops in brachial-ankle pulse wave velocity beyond mere pressure effects. It protects the heart and kidneys through anti-sclerotic and antioxidant actions, lowering cardiovascular event risks.\n​\n\nPatients experience fewer angina attacks, better endurance, and improved quality of life. The once-daily regimen boosts adherence, while vascular selectivity minimizes reflex tachycardia common in other blockers. Clinical data indicate reduced C-reactive protein and aldosterone, curbing inflammation and fibrosis.\n​\n\nBenefit\tDescription\tSupporting Evidence\nBP Control\tReduces systolic/diastolic pressure effectively over 24 hours \n​\tLong-term studies show persistent effects post-treatment \n​\nHeart Protection\tImproves coronary flow, cuts angina frequency \n​\tMyocardial protection via NO stimulation \n​\nRenal Support\tLowers proteinuria, aids kidney hypertension \n​\tAnti-oxidative vascular benefits \n​\nAdherence Ease\tOnce-daily dosing with sustained release \n​\tHigh membrane affinity for lasting action \n​\nAdditional perks include potential triglyceride reduction and osteoblast stimulation for bone health in hypertensives.\n\nPotential Side Effects\nMost users tolerate BENIPRIME 4 well, with mild, transient effects resolving spontaneously. Common issues include headache, dizziness, flushing, ankle swelling, palpitations, fatigue, nausea, and sleepiness.\n​\n\nLess frequent are constipation, abdominal pain, tinnitus, shoulder stiffness, urinary frequency, or elevated liver enzymes. Rare serious reactions involve severe hypotension, rash, itching, or allergic responses—seek immediate care if these arise. Monitor blood pressure during initiation to avoid drops.\n\nHeart-related: Palpitations, chest pressure\n​\n\nNervous system: Dizziness, headache\n\nSkin/Vascular: Flushing, edema.\n\nGI: Nausea, constipation\n​\n\nLiver/kidney patients need caution; inform doctors of history.\n\n\nPrecautions and Interactions\nAvoid in hypotension, severe aortic stenosis, or hypersensitivity to dihydropyridines. Use cautiously in liver/kidney impairment, pregnancy, or breastfeeding—benefits must outweigh risks. Grapefruit juice may amplify effects; limit alcohol.\n​\n\nIt interacts with beta-blockers, digoxin, or CYP3A4 inhibitors like ketoconazole, potentially enhancing hypotension. Regular monitoring of BP, electrolytes, and renal function is advised during therapy. Abrupt stop may rebound pressure; taper under guidance.\n​\nConclusion\nBENIPRIME 4 with Benidipine 4 mg empowers reliable hypertension and angina control through innovative calcium channel action. Balancing potent benefits like organ protection and ease of use against manageable side effects, it fits seamlessly into modern cardiac care. Consult healthcare providers for tailored integration with lifestyle for lasting heart health. ", "price": 89.0, "discountamount": 27.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2261, "imageuri": "https://productimages.withfloats.com/actual/6958dbfc615a7d157715572f.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/6958dbfc615a7d157715572f.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-03T09:06:02.841Z", "updatedon": "2026-03-13T06:54:02.808Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//benidipine-4mg/2261", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "BENIPRIME 4", "category": "CARDIOLOGYRANGE", "tags": [ "benidipine 4mg", "benidipine 4mg tab", "benidipine hydrochloride uses.", "benidipine.", "benidipine 4 mg", "benidipine 4", "benidipine maximum dose", "benidipine 4 mg uses.", "benidipine price" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "693c0f0df827a9801a26dcd7", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide mononitrate IP 60mg Tablets", "description": "CARDULES ISMN SR 60 delivers Isosorbide Mononitrate IP 60mg in a sustained-release tablet form, designed for long-term prevention of angina in patients with coronary artery disease. Produced by Steris Healthcare Pvt Ltd, this formulation ensures steady drug release over 12-24 hours, optimizing cardiovascular protection with once-daily dosing convenience. It supports heart health by enhancing blood flow without the peaks and troughs of immediate-release options.​\n\nProduct Overview\nCARDULES ISMN SR 60 contains Isosorbide Mononitrate IP 60mg per sustained-release tablet, a pure nitrate metabolite that bypasses first-pass liver metabolism for consistent bioavailability. The SR technology employs a polymer matrix to gradually liberate the active ingredient, maintaining therapeutic plasma levels throughout the day and minimizing tolerance development associated with frequent dosing. Available in strips of 10 tablets, it features a film-coated exterior for easy swallowing and gastro-resistant properties to protect against stomach acid degradation.​\n\nThis higher 60mg strength suits patients requiring intensified prophylaxis after initial titration from lower doses like 30mg or 40mg. It integrates seamlessly into comprehensive cardiac regimens alongside beta-blockers, statins, or aspirin, under cardiologist supervision. Quality manufacturing adheres to IP standards, ensuring purity above 99% with low impurity profiles for safety in chronic use.​\n\nKey Uses\nCARDULES ISMN SR 60 primarily prevents chronic stable angina pectoris by dilating coronary arteries and reducing myocardial oxygen demand during exertion. Patients experience fewer episodes of chest tightness, pressure, or discomfort triggered by physical activity, stress, or cold exposure.​\n\nIt manages coronary artery disease (CAD) by improving collateral circulation and easing ischemia in narrowed vessels. Often prescribed post-angioplasty or alongside lifestyle modifications, it stabilizes symptoms for enhanced daily functioning.​\n\nAdditionally, it supports adjunctive therapy in congestive heart failure or post-myocardial infarction recovery, where vasodilation unloads the heart. Not for acute attacks—use sublingual nitroglycerin instead—but vital for long-term risk reduction.​\n\nMajor Benefits\nThe sustained-release profile of CARDULE ISMN SR 60 provides 24-hour angina prevention with single morning dosing, improving adherence over multiple-daily regimens. This steady vasodilation lowers preload via venous pooling and afterload via arterial relaxation, cutting oxygen consumption by up to 20-30% during stress.​\n\nPatients report increased exercise tolerance, with treadmill tests showing delayed onset of ST-segment depression. Enhanced myocardial perfusion boosts energy levels, enabling a return to work, hobbies, or family activities without fear of sudden symptoms.​\n\nCompared to shorter-acting nitrates, tolerance buildup is slower due to a nitrate-free interval built into once-daily use. Cost-effective at higher strengths, it reduces overall healthcare visits and hospitalization risks from unstable angina.​\n\nBenefit\tMechanism\tClinical Advantage\nAngina Prevention\tVasodilation reduces preload/afterload. ​\tFewer episodes, better quality of life\nExercise Capacity\tImproved coronary flow ​\tExtended activity duration by 50%+\nDosing Simplicity\tSR once daily ​\t90% adherence rate vs. multiple doses\nHeart Protection\tLowers ischemia risk. ​\tReduced MI recurrence\nPotential Side Effects\nCommon effects include headache (orthostatic or throbbing), especially in the first week, resolving with hydration and dose acclimation—acetaminophen helps manage it. Dizziness, lightheadedness, or postural hypotension may occur; rise slowly from sitting.​\n\nGastrointestinal upset like nausea or flushing affects 5-10% initially. Avoid alcohol or PDE5 inhibitors (e.g., sildenafil) to prevent severe hypotension.​\n\nRarely, reflex tachycardia, rash, or methemoglobinemia arises; monitor liver enzymes in prolonged use. Contraindicated in severe anemia, glaucoma, or recent PDE5 intake—discontinue if allergic reactions appear.​\n\nDosage Guidelines\nInitiate at 30-40mg daily, titrating to 60mg once in the morning on an empty stomach for optimal absorption. Swallow whole; do not crush. A 10-12 hour nitrate-free window (nighttime) prevents tolerance.​\n\nAdjust for renal/hepatic impairment; max 120mg/day. Store below 25°C. Regular ECG and BP checks ensure efficacy.​\nConclusion\nCARDULES ISMN SR 60 stands as a cornerstone in angina prophylaxis, empowering CAD patients with reliable, sustained vascular relief from Steris Healthcare. Consistent use alongside diet, exercise, and smoking cessation maximizes outcomes, but cardiologist oversight remains essential for safety", "price": 155.0, "discountamount": 47.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2244, "imageuri": "https://productimages.withfloats.com/actual/693c0f14d878634fd7a965ca.png", "tileimageuri": "https://productimages.withfloats.com/tile/693c0f14d878634fd7a965ca.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-12T12:48:13.762Z", "updatedon": "2026-03-14T08:23:14.824Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//isosorbide-mononitrate-ip-60mg-tablets/2244", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CARDULES ISMN SR 60", "category": "cardiology", "tags": [ "Isosorbide mononitrate IP 60mg Tablets", "coronary artery disease", "supports heart health by enhancing blood flow", "gastro-resistant properties to protect against stomach acid", "Contraindicated in severe anemia, glaucoma, or recent PDE5", "coronary artery disease.", "It supports heart health by enhancing blood.", "isosorbide mononitrate 60mg.", "isosorbide 60mg.", "isosorbide mononitrate.", "isosorbide dinitrate tablet uses in hindi", "isosorbide", "isosorbide mononitrate uses", "isosorbide mononitrate 30 mg", "isosorbide mononitrate tablet uses in hindi" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "693c0c9c0c30ac5c9f8203b4", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Isosorbide Mononitrate IP 30mg Tablets", "description": "CARDULES ISMN SR 30 tablets provide sustained-release Isosorbide Mononitrate IP 30mg, a nitrate medication designed for long-term management of angina in patients with coronary artery disease. This formulation from Steris Healthcare Pvt Ltd ensures steady vasodilation to improve heart blood flow and reduce chest pain episodes. It supports daily activities by minimizing oxygen demand on the heart muscle.​\nProduct Overview\nCARDULES ISMN SR 30 contains Isosorbide Mononitrate IP 30mg in a sustained-release matrix, allowing once-daily dosing for consistent therapeutic levels over 12-24 hours. The tablet's extended-release technology prevents peak-trough fluctuations common in immediate-release forms, promoting better patient compliance. Each film-coated tablet delivers precise bioavailability, with the active metabolite nitric oxide activating guanylate cyclase to boost cyclic GMP, relaxing vascular smooth muscle primarily in veins.​\n\nThis mechanism reduces preload (venous return to the heart) and afterload (arterial resistance), easing cardiac workload without significantly affecting heart rate. Unlike short-acting nitrates for acute relief, CARDULES ISMN SR 30 targets prophylaxis in chronic stable angina, often prescribed alongside beta-blockers or calcium channel blockers. Available in strips of 10 tablets, it undergoes rigorous quality testing at Steris facilities to meet IP standards, ensuring purity and stability.​\n\nKey Uses\nCARDULES ISMN SR 30 primarily prevents angina pectoris in coronary artery disease, where narrowed vessels limit oxygen supply during exertion. Patients experience fewer chest pain attacks during walking, climbing stairs, or stress.​\n\nIt manages chronic stable angina by enhancing myocardial perfusion, suitable for long-term therapy in adults over 18. Healthcare providers may use it adjunctively for coronary spasm or post-myocardial infarction prophylaxis to stabilize symptoms.​\n\nIn select cases, it aids heart failure management by offloading the heart, though not as monotherapy. Always initiate under cardiology supervision with dose titration to tolerance.​\n\nMajor Benefits\nThe sustained-release profile offers 24-hour protection with single morning dosing, improving adherence and lifestyle quality for active patients. It boosts exercise tolerance by 20-30% in trials, allowing longer physical efforts without angina onset.​\n\nBy dilating vessels, it decreases ischemia risk, potentially lowering hospitalization rates for acute episodes. Compared to placebo, users report halved attack frequency within weeks, enhancing daily productivity and emotional well-being.​\n\nBenefit\tMechanism\tPatient Outcome\nAngina Prevention\tVasodilation reduces preload/afterload ​\tFewer attacks, better exertion capacity\nSteady Relief\tSR formulation maintains levels ​\tOnce-daily convenience, no fluctuations\nHeart Protection\tImproves O2 delivery ​\tReduced ischemia, enhanced QoL\nCompliance Boost\tSimple regimen ​\tHigher adherence vs multiple doses\nAdditional perks include minimal impact on blood pressure in normotensives and compatibility with anti-anginals, making it versatile in combo therapy.\n\nPotential Side Effects\nCommon effects include headache (dose-related, often transient in first week), dizziness, or flushing due to vasodilation—hydrate and rise slowly to manage. Gastrointestinal upset like nausea occurs in 5-10% initially.​\n\nOrthostatic hypotension risks fainting, especially early; avoid alcohol or other vasodilators. Rare serious issues encompass severe hypotension, tachycardia, or methemoglobinemia with overdose—monitor blood pressure regularly.​\n\nAllergic reactions (rash, itching) or vision changes warrant discontinuation. Contraindicated in hypotension, glaucoma, or recent PDE5 inhibitor use; caution in anemia or hypothyroidism.​\n\nDosage Guidelines\nStart with 30mg once daily upon waking, swallowed whole without crushing. Titrate to 60mg if tolerated after 3-7 days, max 120mg/day. Take on empty stomach for optimal absorption; avoid late dosing to prevent nocturnal headaches.​\n\nAdjust for elderly or renal/hepatic impairment. Tolerance may develop—nitrate-free interval (evening) helps sustain efficacy. Store below 30°C.​\nConclusion\nCARDULES ISMN SR 30 empowers angina patients with reliable, once-daily prevention, restoring confidence in routine activities under Steris Healthcare's quality assurance. Its targeted vasodilation balances efficacy and tolerability for sustained heart health", "price": 65.0, "discountamount": 19.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2243, "imageuri": "https://productimages.withfloats.com/actual/693c0ca6391a3fa44b0608d8.png", "tileimageuri": "https://productimages.withfloats.com/tile/693c0ca6391a3fa44b0608d8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-12T12:37:48.92Z", "updatedon": "2026-03-14T08:21:58.091Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//isosorbide-mononitrate-ip-30mg-tablets/2243", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CARDULES ISMN SR 30", "category": "", "tags": [ "Isosorbide Mononitrate IP 30mg Tablets", "coronary artery disease", "heart blood flow and reduce chest pain episodes", "oxygen demand on the heart muscle", "relaxing vascular smooth muscle primarily in veins" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "69142bf71d499513a92e5772", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nicorandil Tablets 5mg", "description": "Nicorandil Tablets 5 mg is a vasodilatory anti-anginal medication widely prescribed for the management and prevention of angina pectoris (chest pain) associated with coronary artery disease (CAD). Angina results from an imbalance between the heart’s oxygen demand and supply due to restricted blood flow in the coronary arteries. Nicorandil offers a dual mechanism of action — acting both as a nitrate-like vasodilator and a potassium channel opener, making it unique among anti-anginal agents.\n\nBy improving oxygen delivery to the myocardium and reducing cardiac workload, Nicorandil 5 mg Tablets provide effective relief from anginal pain and reduce the frequency and severity of ischemic episodes. It is also beneficial in preventing future attacks, improving exercise tolerance, and enhancing the overall quality of life in patients with chronic stable angina.\n\nComposition\n\nEach tablet contains:\n\nNicorandil IP – 5 mg\n\nExcipients – q.s.\n\nNicorandil tablets are available in film-coated form to ensure stability, easy swallowing, and optimal absorption. They are manufactured in compliance with Good Manufacturing Practices (GMP) standards to ensure safety, purity, and efficacy.\n\nPharmacological Action / Mechanism of Action\n\nNicorandil exhibits a dual mechanism that makes it distinct among anti-anginal drugs:\n\nNitrate-Like Effect:\nNicorandil acts as a nitric oxide (NO) donor. Nitric oxide activates guanylate cyclase, increasing cyclic GMP (cGMP) levels in vascular smooth muscle. This leads to relaxation of blood vessels, particularly veins and large arteries, thereby reducing preload and afterload on the heart. This nitrate-like activity lowers myocardial oxygen demand.\n\nPotassium Channel Opening Effect:\nNicorandil opens ATP-sensitive potassium (KATP) channels in vascular smooth muscle, resulting in arteriolar vasodilation. This increases coronary blood flow and improves oxygen supply to ischemic heart tissues.\n\nTogether, these effects reduce cardiac workload, enhance coronary perfusion, and prevent anginal pain by correcting the oxygen supply-demand mismatch in the heart muscle.\n\nUses and Indications\n\nNicorandil Tablets 5 mg are indicated for the treatment and prevention of angina pectoris in adults, particularly:\n\nChronic Stable Angina:\n\nHelps reduce the frequency and severity of chest pain associated with exertion or emotional stress.\n\nProphylaxis of Angina Attacks:\n\nUsed regularly to prevent anginal episodes, especially in patients with known coronary artery disease.\n\nAdjunct Therapy in Ischemic Heart Disease (IHD):\n\nCan be used alongside beta-blockers, calcium channel blockers, or antiplatelet drugs for enhanced symptom control and long-term protection.\n\nImprovement of Exercise Tolerance:\n\nReduces the likelihood of anginal pain during physical activity, enabling patients to perform daily tasks comfortably.\n\nIn some clinical cases, Nicorandil is also considered for post-myocardial infarction recovery, as it improves coronary perfusion, although this is at the discretion of a cardiologist.\n\nDosage and Administration\n\nRecommended Starting Dose: 5 mg to 10 mg twice daily.\n\nMaintenance Dose: May be increased gradually to 10–20 mg twice daily, depending on clinical response and tolerance.\n\nThe tablets should be swallowed whole with water, preferably at the same times each day.\n\nNicorandil should not be stopped abruptly; dosage tapering is recommended to avoid rebound angina.\n\nAlways follow the dosage instructions provided by the physician.\n\nKey Benefits\n\nDual Mechanism for Comprehensive Relief:\nCombines nitrate-like and potassium channel-opening properties for both arterial and venous dilation, providing superior protection against anginal attacks.\n\nImproves Coronary Blood Flow:\nDilates coronary arteries, increasing oxygen delivery to ischemic myocardial tissues.\n\nReduces Cardiac Workload:\nBy decreasing preload (venous return) and afterload (arterial resistance), Nicorandil minimizes the heart’s oxygen consumption.\n\nRapid Onset of Action:\nNicorandil acts within a short duration, offering quick relief from anginal discomfort.\n\nPrevents Future Angina Episodes:\nRegular use helps maintain steady control of chest pain, improving exercise capacity and quality of life.\n\nCompatible with Other Cardiac Medications:\nCan be safely used alongside antiplatelet agents, beta-blockers, ACE inhibitors, and statins as part of comprehensive cardiac care.\n\nFavorable Safety Profile:\nCompared to nitrates, Nicorandil carries a lower risk of tolerance development, making it suitable for long-term therapy.\n\nEnhances Myocardial Protection:\nNicorandil’s KATP channel activation provides additional cardioprotective effects by improving microvascular blood flow and limiting ischemic damage during stress.\n\nPrecautions and Warnings\n\nAlthough Nicorandil is generally well-tolerated, certain precautions are advised:\n\nHypotension:\nNicorandil may cause a drop in blood pressure due to vasodilation. Caution is advised in patients with hypotension or dehydration.\n\nConcurrent Use with Nitrates:\nShould not be used together with other nitrate medications to avoid severe hypotension.\n\nOral or Gastrointestinal Ulcers:\nRarely, Nicorandil may cause ulcerations in the mouth, intestines, or skin. Treatment should be discontinued if ulceration occurs.\n\nPatients with Low Blood Volume:\nUse cautiously in individuals with hypovolemia or those on diuretics.\n\nDriving and Machinery:\nDizziness or light-headedness may occur; avoid driving until effects are known.\n\nPregnancy and Lactation:\nShould be used only if prescribed by a physician when the potential benefits outweigh the risks.\n\nPossible Side Effects\n\nNicorandil is generally safe but may cause some side effects, particularly at the start of therapy or with higher doses. Common and rare adverse reactions include:\n\nCommon Side Effects:\n\nHeadache (due to vasodilation)\n\nFlushing or warmth sensation\n\nDizziness or light-headedness\n\nNausea or mild stomach upset\n\nFatigue or weakness\n\nLess Common / Rare Side Effects:\n\nHypotension (low blood pressure)\n\nPalpitations or tachycardia\n\nMouth ulcers, anal ulcers, or skin ulceration (uncommon but serious — discontinue if occurs)\n\nRash or allergic reaction\n\nVisual disturbances (rare and usually reversible)\n\nIf any severe reaction or persistent discomfort occurs, medical attention should be sought promptly.\n\nDrug Interactions\n\nAvoid concomitant use with nitrates or phosphodiesterase type-5 inhibitors (e.g., Sildenafil, Tadalafil), as it may cause a dangerous fall in blood pressure.\n\nCaution with antihypertensive drugs or diuretics, which may enhance hypotensive effects.\n\nAlcohol consumption can potentiate dizziness or hypotension and should be limited.\n\nStorage and Handling\n\nStore below 30°C, protected from moisture and direct sunlight.\n\nKeep out of reach of children.\n\nDo not use tablets past the expiry date or if the packaging is damaged.\n\nConclusion\n\nNicorandil Tablets 5 mg offer a modern and effective approach to managing angina pectoris, providing reliable relief through their dual-action mechanism. By combining nitrate-like vasodilation with potassium channel opening, Nicorandil ensures both oxygen supply improvement and reduction of cardiac workload — the cornerstone of angina management.\n\nIt is well-tolerated, fast-acting, and suitable for long-term therapy, making it a preferred choice for patients with chronic stable angina. Regular use under medical supervision helps reduce the frequency of chest pain, improve physical endurance, and enhance the overall quality of life in individuals with coronary artery disease.", "price": 381.0, "discountamount": 115.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2202, "imageuri": "https://productimages.withfloats.com/actual/69142c03b53db80943abd33d.png", "tileimageuri": "https://productimages.withfloats.com/tile/69142c03b53db80943abd33d.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-11-12T06:40:55.795Z", "updatedon": "2026-03-16T08:18:00.245Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//nicorandil-tablets-5mg/2202", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "MAYORANDIL 5 ", "category": "CARDIOLOGYRANGE", "tags": [ "nicorandil tablets 5mg", "nicorandil 5 mg tablets uses", "nicorandil tablet 5mg benefits", "nicorandil 5mg medicine", "nicorandil tablets ip 5 mg", "what is nicorandil 5mg used for", "how does nicorandil tablet work", "nicorandil 5mg mechanism of action", "nicorandil tablets for angina treatment", "nicorandil tablet uses in heart disease", "nicorandil 5mg tablet price in india", "buy nicorandil 5mg tablets online", "nicorandil 5mg tablet brands", "nicorandil tablets manufacturer", "nicorandil tablets wholesale supplier" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6827200ed43a11f501af2c5f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Nifedipine 5mg", "description": "NIFEDULES 5 is a prescription medication containing Nifedipine 5mg, a well-known calcium channel blocker used to manage high blood pressure (hypertension), angina (chest pain), and other cardiovascular conditions. It works by improving blood flow and reducing the workload on the heart, offering reliable relief and long-term management of heart-related symptoms. NIFEDULES 5 helps maintain a healthy cardiovascular system and prevents complications associated with high blood pressure.\n\nKey Ingredient\nNifedipine 5mg\nNifedipine belongs to the class of medications known as dihydropyridine calcium channel blockers. It is effective in dilating blood vessels, improving circulation, and reducing the heart’s effort in pumping blood.\n\nKey Benefits\nHelps control and lower high blood pressure\n\nRelieves chronic stable angina and variant angina\n\nImproves oxygen delivery to the heart\n\nPrevents chest pain during physical or emotional stress\n\nReduces the risk of stroke and heart attack\n\nSupports better heart function and circulation\n\nOffers rapid onset of action in certain formulations\n\nHow Does It Work?\nNIFEDULES 5 works by inhibiting the influx of calcium ions into the smooth muscles of the heart and blood vessels. By blocking calcium entry, it causes relaxation of the vascular smooth muscles, resulting in the dilation of arteries. This leads to decreased vascular resistance, improved blood flow, and reduced blood pressure. For angina patients, it decreases the oxygen demand of the heart, helping prevent chest pain.\n\nDirections for Use\nTake the medication exactly as prescribed by your doctor\n\nUsually taken orally with or without food\n\nSwallow the tablet whole with water; do not crush or chew\n\nFollow a consistent schedule daily to maintain steady drug levels\n\nDo not abruptly stop the medication without consulting your healthcare provider\n\nSide Effects\nHeadache\n\nFlushing (warmth, redness in face or neck)\n\nDizziness or light-headedness\n\nSwelling in the ankles or feet\n\nNausea or upset stomach\n\nRapid heartbeat or palpitations\n\nFatigue or weakness\n\nRare but serious: low blood pressure, severe chest pain, or allergic reaction\n\n", "price": 28.0, "discountamount": 9.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": [ "prescription medication", "allergic reaction", "weakness rare", "palpitations fatigue", "feet nausea", "lightheadedness swelling", "neck dizziness", "abruptly stop", "chew follow", "food swallow", "oxygen demand", "angina patients", "smooth muscles", "heart function", "hearts effort", "prevents complications", "longterm management", "nifedipine 5mg", "nifedules 5nifedules 5", "calcium ions", "cardiovascular conditions", "blood vessels", "heart attack supports", "blocking calcium entry", "healthy cardiovascular system", "reduced blood pressure", "improving blood flow", "consistent schedule daily", "emotional stress reduces" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2115, "imageuri": "https://productimages.withfloats.com/actual/68272010de3c95a1760cd413.png", "tileimageuri": "https://productimages.withfloats.com/tile/68272010de3c95a1760cd413.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-05-16T11:22:54.123Z", "updatedon": "2026-03-13T12:35:06.958Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//nifedipine-5mg/2115", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "Steris Healthcare Pvt Ltd", "category": "CARDIOLOGYRANGE", "tags": [ "Nifedipine 5mg Price", "Nifedipine dosage", "Nifedipine 5mg Uses in Hindi", "Nifedipine 5mg uses" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false } ], "hasmoreitems": false, "isapirequest": false, "totalresults": 27, "query": null, "floatingpoint": null }