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{ "products": [ { "_id": "6958dbfa1063d98b1e8f2fe1", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Benidipine 4mg", "description": "BENIPRIME 4, containing Benidipine 4 mg, offers effective management for high blood pressure and related heart conditions. This calcium channel blocker helps relax blood vessels to improve blood flow and reduce strain on the heart. Patients often find it reliable for daily control of hypertension symptoms.\n\nWhat is BENIPRIME 4?\nBENIPRIME 4 is a branded tablet from Steris Healthcare Pvt Ltd, featuring 4 mg of Benidipine as the active ingredient. Benidipine belongs to the dihydropyridine class of calcium channel blockers, designed specifically for cardiovascular health. Each tablet delivers a precise dose in a user-friendly form, typically packaged in strips of 10 for convenient use. Manufactured under strict quality standards, it targets essential needs in hypertension care, making it a staple in many treatment plans across India.\n​\n\nThis medication stands out due to its triple action on L-type, N-type, and T-type calcium channels, providing broader vascular protection compared to some other blockers. Doctors prescribe it for adults dealing with persistent high blood pressure or chest pain, often starting at this 4 mg strength for balanced efficacy. Unlike generic options, BENIPRIME 4 ensures consistent absorption and formulation tailored for Indian patients, with pricing around Rs 62-89 per strip after discounts.\n​\n\nHow BENIPRIME 4 Works\nBenidipine in BENIPRIME 4 blocks calcium entry into smooth muscle cells of blood vessels and heart muscles. This action causes vasodilation, widening arteries to lower resistance and ease blood flow. By reducing systolic and diastolic pressure, it lightens the heart's workload without drastically slowing the heartbeat.\n​\n\nThe unique blockade of multiple calcium channels also boosts nitric oxide production, offering antioxidant effects and protection against artery hardening. This sustained mechanism provides 24-hour control, ideal for once-daily dosing after breakfast. Over time, it may even reduce urinary protein and triglycerides, supporting kidney and metabolic health in hypertensives.\n​\n\nKey Uses of BENIPRIME 4\nBENIPRIME 4 primarily treats essential hypertension, helping prevent strokes, heart attacks, and kidney damage. It effectively manages angina pectoris by enhancing coronary blood supply, reducing chest pain episodes during activity.\n​\n\nPhysicians also use it for renal parenchymal hypertension, where kidney issues elevate blood pressure. In emergencies like hypertensive crises or subarachnoid hemorrhage, higher doses prove beneficial, though 4mg serves as maintenance. For arrhythmia or anal fissures linked to vascular strain, it offers supportive relief.\n​\n\nLowers high blood pressure in adults, including severe cases with dose adjustments.\n​\n\nEases angina symptoms, improving exercise tolerance and daily life quality.\n​\n\nProtects renal function in proteinuric patients by stabilizing vessels.\n​\n\nDosage and Administration\nTake BENIPRIME 4 as 4 mg once daily, swallowed whole after a meal to minimize stomach upset. Doctors may adjust to 2-8mg based on response, age, or kidney/liver status, never exceeding 8 mg daily without monitoring. Consistency in timing ensures steady levels for optimal pressure control.\n​\n\nMissed doses require prompt intake if remembered soon, but skip if near the next one—avoid doubles. Pair with lifestyle changes like low-salt diets and exercise for best results. Always consult for personalization, especially in elderly or comorbid patients.\n​\n\nKey Benefits\nBENIPRIME 4 excels in long-term blood pressure reduction, with studies showing sustained drops in brachial-ankle pulse wave velocity beyond mere pressure effects. It protects the heart and kidneys through anti-sclerotic and antioxidant actions, lowering cardiovascular event risks.\n​\n\nPatients experience fewer angina attacks, better endurance, and improved quality of life. The once-daily regimen boosts adherence, while vascular selectivity minimizes reflex tachycardia common in other blockers. Clinical data indicate reduced C-reactive protein and aldosterone, curbing inflammation and fibrosis.\n​\n\nBenefit\tDescription\tSupporting Evidence\nBP Control\tReduces systolic/diastolic pressure effectively over 24 hours \n​\tLong-term studies show persistent effects post-treatment \n​\nHeart Protection\tImproves coronary flow, cuts angina frequency \n​\tMyocardial protection via NO stimulation \n​\nRenal Support\tLowers proteinuria, aids kidney hypertension \n​\tAnti-oxidative vascular benefits \n​\nAdherence Ease\tOnce-daily dosing with sustained release \n​\tHigh membrane affinity for lasting action \n​\nAdditional perks include potential triglyceride reduction and osteoblast stimulation for bone health in hypertensives.\n\nPotential Side Effects\nMost users tolerate BENIPRIME 4 well, with mild, transient effects resolving spontaneously. Common issues include headache, dizziness, flushing, ankle swelling, palpitations, fatigue, nausea, and sleepiness.\n​\n\nLess frequent are constipation, abdominal pain, tinnitus, shoulder stiffness, urinary frequency, or elevated liver enzymes. Rare serious reactions involve severe hypotension, rash, itching, or allergic responses—seek immediate care if these arise. Monitor blood pressure during initiation to avoid drops.\n\nHeart-related: Palpitations, chest pressure\n​\n\nNervous system: Dizziness, headache\n\nSkin/Vascular: Flushing, edema.\n\nGI: Nausea, constipation\n​\n\nLiver/kidney patients need caution; inform doctors of history.\n\n\nPrecautions and Interactions\nAvoid in hypotension, severe aortic stenosis, or hypersensitivity to dihydropyridines. Use cautiously in liver/kidney impairment, pregnancy, or breastfeeding—benefits must outweigh risks. Grapefruit juice may amplify effects; limit alcohol.\n​\n\nIt interacts with beta-blockers, digoxin, or CYP3A4 inhibitors like ketoconazole, potentially enhancing hypotension. Regular monitoring of BP, electrolytes, and renal function is advised during therapy. Abrupt stop may rebound pressure; taper under guidance.\n​\nConclusion\nBENIPRIME 4 with Benidipine 4 mg empowers reliable hypertension and angina control through innovative calcium channel action. Balancing potent benefits like organ protection and ease of use against manageable side effects, it fits seamlessly into modern cardiac care. Consult healthcare providers for tailored integration with lifestyle for lasting heart health. ", "price": 89.0, "discountamount": 27.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2261, "imageuri": "https://productimages.withfloats.com/actual/6958dbfc615a7d157715572f.jpg", "tileimageuri": "https://productimages.withfloats.com/tile/6958dbfc615a7d157715572f.jpg", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-01-03T09:06:02.841Z", "updatedon": "2026-03-13T06:54:02.808Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/benidipine-4mg/2261", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "BENIPRIME 4", "category": "CARDIOLOGYRANGE", "tags": [ "benidipine 4mg", "benidipine 4mg tab", "benidipine hydrochloride uses.", "benidipine.", "benidipine 4 mg", "benidipine 4", "benidipine maximum dose", "benidipine 4 mg uses.", "benidipine price" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "671f5940fd6220a4afeba209", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Ramipril (2.5 mg)", "description": "REMINIL 2.5 is a trusted medication designed to manage high blood pressure and reduce the risk of heart-related complications. Its active ingredient, Ramipril (2.5 mg), belongs to a class of drugs known as ACE inhibitors. By helping to relax blood vessels, REMINIL 2.5 plays a crucial role in promoting heart health and improving overall circulation. This medication is ideal for patients who require effective blood pressure control and want to safeguard their cardiovascular health.\n\n \nKey Benefits:\n \n\nEffective Blood Pressure Control: REMINIL 2.5 helps lower high blood pressure, reducing the risk of heart attack and stroke.\n\nCardiovascular Protection: By improving blood flow and decreasing the heart's workload, this medication aids in protecting against heart-related complications.\n\nKidney Health Support: Ramipril has been shown to be beneficial for kidney function, particularly in patients with diabetes or chronic kidney disease.\n\nImproved Quality of Life: By managing hypertension effectively, REMINIL 2.5 contributes to an improved overall quality of life for patients, allowing them to engage in daily activities without concern for their cardiovascular health.\n\n \nHow Does It Work?\n \n\nREMINIL 2.5 works by inhibiting the action of the angiotensin-converting enzyme (ACE), which plays a key role in the body’s renin-angiotensin-aldosterone system (RAAS). By blocking ACE, Ramipril prevents the formation of angiotensin II, a hormone that constricts blood vessels. The result is:\n\nVasodilation: Blood vessels relax and widen, which decreases resistance and lowers blood pressure.\nReduced Fluid Retention: By decreasing the secretion of aldosterone, REMINIL 2.5 helps reduce sodium and fluid retention, further assisting in blood pressure control.\nThis mechanism not only lowers blood pressure but also protects the heart and kidneys from damage caused by high blood pressure.\n\n \nDirections for Use:\n \nDosage: The recommended starting dose for adults is typically 2.5 mg once daily, but the dosage may be adjusted based on individual response and medical advice.\nAdministration: Take REMINIL 2.5 orally with a full glass of water. It can be taken with or without food, but consistency in how you take it is essential for maintaining even levels in your bloodstream.\nFollow-up: Regular check-ups with your healthcare provider are crucial to monitor blood pressure and adjust the dosage if necessary.\n \nSide Effects:\n \nWhile REMINIL 2.5 is generally well-tolerated, some individuals may experience side effects. Common side effects include:\n\nDizziness or lightheadedness: This may occur, particularly after the first dose or when increasing the dosage.\nCough: A persistent dry cough is a known side effect of ACE inhibitors.\nFatigue: Some patients may feel unusually tired.", "price": 49.9, "discountamount": 14.97, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "2.5 mg", "key role", "first dose", "full glass", "blood flow", "heart attack", "heart health", "Key Benefits", "crucial role", "starting dose", "blood vessels", "ACE inhibitors", "medical advice", "angiotensin II", "overall quality", "kidney function", "Improved Quality", "daily activities", "Regular check-ups", "active ingredient", "trusted medication", "healthcare provider", "individual response", "overall circulation", "Common side effects", "high blood pressure", "persistent dry cough", "cardiovascular health", "Kidney Health Support", "chronic kidney disease", "Reduced Fluid Retention", "Cardiovascular Protection", "heart-related complications", "angiotensin-converting enzyme", "effective blood pressure control", "renin-angiotensin-aldosterone system" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2002, "imageuri": "https://productimages.withfloats.com/actual/671f59450b46eeb6b9abe2db.png", "tileimageuri": "https://productimages.withfloats.com/tile/671f59450b46eeb6b9abe2db.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-10-28T09:28:32.347Z", "updatedon": "2026-03-16T08:42:38.297Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//ramipril-2-5-mg-/2002", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "REMINIL 2.5 ", "category": "CARDIOLOGYRANGE", "tags": [ "Reminyl side effects", "What is Reminyl used to treat", "" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6666e66b3b4bb822140484eb", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": " S LACTONE 50", "description": "S LACTONE 50\nSpironolactone (50mg)\nS Lactone 50 is a medication containing Spironolactone 50mg, commonly used to treat conditions like high blood pressure, heart failure, and edema (fluid retention). Here's a concise description:\n\n\"S Lactone 50 (Spironolactone 50mg) is a diuretic medication that helps reduce fluid retention and lower blood pressure. It is used to treat conditions such as hypertension and heart failure, often in combination with other drugs. Spironolactone works by blocking the effects of aldosterone, a hormone that regulates water and salt balance in the body. This medication is available in tablet form and is typically taken once daily as directed by a healthcare provider.\"\n\nFor further information:\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nORDER Now: \nhttps://www.sterisonline.com/product/s-lactone-50-133985\n\n\n\n\n\n\n", "price": 47.0, "discountamount": 14.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "body", "Call", "ORDER", "water", "edema", "Email", "hormone", "effects", "WhatsApp", "S LACTONE", "conditions", "other drugs", "information", "tablet form", "combination", "aldosterone", "sterispharma", "sterisonline", "salt balance", "hypertension", "heart failure", "fluid retention", "Spironolactone 50mg", "diuretic medication", "healthcare provider", "concise description", "high blood pressure", "lower blood pressure" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1687, "imageuri": "https://productimages.withfloats.com/actual/667d3de5b5672189851111b8.png", "tileimageuri": "https://productimages.withfloats.com/tile/667d3de5b5672189851111b8.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-10T11:41:31.761Z", "updatedon": "2026-03-16T10:05:39.853Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//-s-lactone-50/1687", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": " S LACTONE 50", "category": "UROLOGYRANGE", "tags": [ "S LACTONE 50", "Spironolactone 50mg side effects", "Spironolactone (50mg)", "Spironolactone (50mg)", "Spironolactone (50mg)", "Spironolactone (50mg)" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6666e5bdc6406f17e8a3906c", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "S LACTONE 25", "description": "S LACTONE 25\nSpironolactone (25mg)\nS Lactone 25 is a medication containing Spironolactone in a 25mg dosage. Spironolactone is a potassium-sparing diuretic that helps reduce fluid retention and lower blood pressure. It works by blocking aldosterone receptors, thereby decreasing sodium and water reabsorption while promoting potassium retention. This dual action makes it useful in conditions like hypertension, edema, and certain hormonal imbalances. S Lactone 25 should be taken as directed by a healthcare professional, typically once daily with or without food. Common side effects may include dizziness, headache, and electrolyte imbalances. It's important to monitor potassium levels regularly while using this medication.For further information:\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nORDER Now: \nhttps://www.sterisonline.com/product/s-lactone-25-133984", "price": 23.0, "discountamount": 7.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "Call", "food", "ORDER", "Email", "edema", "sodium", "product", "WhatsApp", "headache", "dizziness", "S LACTONE", "conditions", "medication", "25mg dosage", "dual action", "information", "sterisonline", "hypertension", "sterispharma", "Spironolactone", "blood pressure", "fluid retention", "potassium levels", "water reabsorption", "Common side effects", "potassium retention", "hormonal imbalances", "aldosterone receptors", "electrolyte imbalances", "healthcare professional", "potassium-sparing diuretic" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1686, "imageuri": "https://productimages.withfloats.com/actual/667d3de3cd6f42ac04609c20.png", "tileimageuri": "https://productimages.withfloats.com/tile/667d3de3cd6f42ac04609c20.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-10T11:38:37.579Z", "updatedon": "2026-03-17T06:35:50.924Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//s-lactone-25/1686", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "S LACTONE 25", "category": "UROLOGYRANGE", "tags": [ "S LACTONE 25", "Spironolactone 25mg uses", "Spironolactone 25mg tablet", "S LACTONE 25", "Spironolactone (25mg)", "Spironolactone (25mg)" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6666e3e8899bdd18a0443ba9", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "S LACTONE 100", "description": "S LACTONE 100\nSpironolactone (100mg)\nS LACTONE 100 contains Spironolactone, a medication used to treat high blood pressure, heart failure, and conditions where the body retains too much salt and water. It belongs to a class of drugs known as aldosterone receptor antagonists.\n\nKey Features:\n\nActive Ingredient: Spironolactone 100mg\nMedication Class: Aldosterone Receptor Antagonist\nUses: High blood pressure, Heart failure, Edema (fluid retention)\nMechanism of Action: Blocks the effects of aldosterone, a hormone that regulates salt and water balance\nDosage: Typically taken once daily or as directed by a healthcare professional\nAdministration: Oral tablets, usually with food to enhance absorption\nSide Effects: May include dizziness, headache, nausea, and changes in potassium levels\nPrecautions: Avoid potassium supplements and monitor electrolytes during treatment For further information:\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nORDER Now: \nhttps://www.sterisonline.com/product/s-lactone-100-133983", "price": 189.0, "discountamount": 57.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "Call", "food", "salt", "body", "drugs", "ORDER", "Email", "Edema", "nausea", "Action", "changes", "hormone", "product", "WhatsApp", "headache", "dizziness", "treatment", "Mechanism", "S LACTONE", "conditions", "absorption", "information", "sterispharma", "electrolytes", "Side Effects", "Key Features", "sterisonline", "Oral tablets", "heart failure", "Spironolactone", "fluid retention", "Medication Class", "Active Ingredient", "high blood pressure", "water balance Dosage", "potassium supplements", "potassium levels Precautions", "aldosterone receptor antagonists", "Aldosterone Receptor Antagonist Uses", "healthcare professional Administration" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1685, "imageuri": "https://productimages.withfloats.com/actual/667d3e19576e8da931df7f31.png", "tileimageuri": "https://productimages.withfloats.com/tile/667d3e19576e8da931df7f31.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-10T11:30:48.727Z", "updatedon": "2026-03-16T10:03:44.955Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//s-lactone-100/1685", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "S LACTONE 100", "category": "UROLOGYRANGE", "tags": [ "S LACTONE 100", "Spironolactone 100mg side effects", "Spironolactone 100mg uses", "Spironolactone (100mg)", "Spironolactone (100mg)" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6666cb32a4e54e1dc4565836", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "FRUSIP PLUS 20", "description": "FRUSIP PLUS 20\nFurosemide (20 mg) & Spironolactone (50mg)\nFrusip Plus 20 is a combination medication that contains two active ingredients, Furosemide and Spironolactone. Furosemide is a diuretic that helps the body remove excess water and salt by increasing urine production. Spironolactone is a potassium-sparing diuretic that prevents the body from absorbing too much salt while retaining potassium.\n\nIndications: Frusip Plus 20 is used to treat conditions such as edema (fluid retention) associated with congestive heart failure, liver cirrhosis, and kidney disorders. It is also prescribed for hypertension (high blood pressure) when other medications are not sufficient.\n\nMechanism of Action: Furosemide works by blocking the absorption of sodium and chloride in the kidneys, leading to increased urine production and decreased fluid retention. Spironolactone works by blocking the actions of aldosterone, a hormone that regulates salt and water balance, thus promoting potassium retention and reducing fluid buildup.\n\nDosage and Administration: The dosage of Frusip Plus 20 is determined by a healthcare provider based on the patient's condition and response to treatment. It is usually taken orally once or twice daily, with or without food. It is important to follow the prescribed dosage and directions for use.\n\nPrecautions and Warnings: Patients taking Frusip Plus 20 should be monitored for electrolyte imbalances, especially potassium levels. It is essential to inform the healthcare provider about any existing medical conditions, allergies, or medications being taken, as they may interact with Frusip Plus 20. Avoid sudden changes in posture to prevent dizziness or lightheadedness.\n\nSide Effects: Common side effects of Frusip Plus 20 may include increased urination, dizziness, headache, nausea, vomiting, and electrolyte imbalances. Serious side effects such as severe allergic reactions or liver problems are rare but should be reported to a healthcare professional immediately.For further information:\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\nORDER Now: \nhttps://www.sterisonline.com/product/frusip-plus-20-133301", "price": 48.0, "discountamount": 15.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "use", "body", "Call", "food", "salt", "Email", "edema", "Dosage", "sodium", "posture", "kidneys", "hormone", "patient", "response", "chloride", "Warnings", "vomiting", "WhatsApp", "headache", "Mechanism", "treatment", "allergies", "dizziness", "increased", "urination", "absorption", "directions", "Furosemide", "aldosterone", "Precautions", "Indications", "information", "FRUSIP PLUS", "sterispharma", "hypertension", "sterisonline", "excess water", "fluid buildup", "water balance", "Administration", "liver problems", "sudden changes", "Spironolactone", "liver cirrhosis", "lightheadedness", "fluid retention", "potassium levels", "urine production", "kidney disorders", "other medications", "potassium retention", "Common side effects", "high blood pressure", "healthcare provider", "Serious side effects", "electrolyte imbalances", "combination medication", "two active ingredients", "healthcare professional", "congestive heart failure", "severe allergic reactions", "potassium-sparing diuretic", "existing medical conditions" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1655, "imageuri": "https://productimages.withfloats.com/actual/6666cb352d43284d726b1150.png", "tileimageuri": "https://productimages.withfloats.com/tile/6666cb352d43284d726b1150.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-10T09:45:22.512Z", "updatedon": "2026-03-16T11:04:03.875Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//frusip-plus-20/1655", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "FRUSIP PLUS 20", "category": "UROLOGYRANGE", "tags": [ "FRUSIP PLUS 20", "Furosemide (20 mg)", "Spironolactone 50mg price", "FRUSIP PLUS 20 uses in hindi", "FRUSIP PLUS 20 usses in hindi" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "665ee8be7b387b17ecbcbde3", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": " SACUBRIGHT 200 ", "description": "SACUBRIGHT 200 \nSacubitril (97mg), Valsartan (103mg)\nSACUBRIGHT 200 is a combination medication containing two active ingredients: Sacubitril (97mg) and Valsartan (103mg). This combination is designed to provide dual inhibition of the renin-angiotensin-aldosterone system (RAAS) for the treatment of heart failure with reduced ejection fraction (HFrEF).\n\nSacubitril is a neprilysin inhibitor, while Valsartan is an angiotensin II receptor blocker (ARB). Together, they work synergistically to improve cardiovascular outcomes in patients with HFrEF by targeting different pathways involved in the pathophysiology of heart failure.\n\nNeprilysin is an enzyme responsible for the degradation of natriuretic peptides, which play a crucial role in regulating blood pressure and fluid balance. By inhibiting neprilysin, Sacubitril increases the levels of natriuretic peptides, leading to vasodilation, natriuresis, and diuresis, which helps reduce blood pressure, preload, and afterload on the heart.\n\nValsartan, as an ARB, blocks the effects of angiotensin II, a vasoconstrictor and stimulator of aldosterone secretion. By antagonizing the angiotensin II type 1 (AT1) receptors, Valsartan dilates blood vessels, reduces blood pressure, and attenuates the deleterious effects of angiotensin II on cardiac remodeling and fibrosis.\n\nSACUBRIGHT 200 is indicated for the treatment of symptomatic HFrEF in patients with New York Heart Association (NYHA) class II-IV heart failure. Clinical studies have demonstrated that this combination therapy reduces the risk of cardiovascular death and hospitalization for heart failure compared to traditional therapy with angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) alone.\n\nAs with any medication, SACUBRIGHT 200 may cause side effects, including hypotension, hyperkalemia, renal impairment, and angioedema. Patients should be monitored regularly for these adverse effects, especially during initiation and dose titration.\n\nOverall, SACUBRIGHT 200 represents an innovative approach to the management of HFrEF, offering superior efficacy and cardiovascular benefits compared to standard therapy. 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