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"name": "glycopyrrolate 25 formoterol 12 budesonide 400",
"description": "BUDESHINE PLUS 400 is an advanced inhalation therapy offered by Steris Healthcare, specially formulated for individuals suffering from chronic respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It combines three potent active ingredients: Budesonide IP (400 mcg), a corticosteroid that reduces airway inflammation; Glycopyrronium (25 mcg), a long-acting anticholinergic that eases bronchial constriction; and Formoterol Fumarate (12 mcg), a long-acting beta-2 agonist that helps in smooth muscle relaxation of the airways. This triple combination ensures comprehensive symptom management, helping patients breathe easier and maintain an active lifestyle.\n\nUses\n\nBUDESHINE PLUS 400 is primarily used for:\n\nManaging and controlling moderate to severe asthma.\n\nTreatment of chronic obstructive pulmonary disease (COPD) to reduce flare-ups.\n\nRelieving wheezing, shortness of breath, and chest tightness associated with airway inflammation.\n\nProviding maintenance therapy for patients requiring long-term control of respiratory symptoms.\n\nBy targeting different pathways of airway obstruction, this combination offers both immediate relief and long-term control of chronic respiratory conditions.\n\nBenefits\n\nThe unique combination of Budesonide, Glycopyrronium, and Formoterol Fumarate in BUDESHINE PLUS 400 provides multiple benefits:\n\nReduces Inflammation: Budesonide helps calm swelling and irritation in the airways, minimizing asthma attacks.\n\nOpens Airways Effectively: Glycopyrronium relaxes the bronchial muscles, enhancing airflow and reducing breathlessness.\n\nLong-Lasting Relief: Formoterol Fumarate ensures sustained bronchodilation, improving lung function for up to 12 hours.\n\nImproved Quality of Life: Regular use helps patients maintain daily activities with fewer respiratory interruptions.\n\nDual Action for Exacerbations: Reduces the frequency and severity of asthma or COPD flare-ups.\n\nDosage\n\nThe dosage of BUDESHINE PLUS 400 should be strictly followed as prescribed by a healthcare professional. Typical guidance includes:\n\nAdults and adolescents (12 years and above): 1–2 inhalations twice daily.\n\nUsage: Shake the inhaler well before each use. Exhale fully, place the mouthpiece in the mouth, and inhale slowly while pressing the canister. Hold the breath for 5–10 seconds for maximum efficacy.\n\nMaintenance: Consistency is key—use the inhaler regularly for optimal long-term benefits.\n\nPatients should avoid exceeding the prescribed dose and consult their doctor before adjusting frequency.\n\nSide Effects\n\nWhile BUDESHINE PLUS 400 is generally well-tolerated, some users may experience:\n\nMild throat irritation or hoarseness\n\nDry mouth\n\nOccasional coughing or nasal congestion\n\nRarely, headache, tremors, or palpitations due to Formoterol\n\nFungal infections in the mouth (oral thrush) from corticosteroid use\n\nMost side effects are manageable and can be minimized by rinsing the mouth after inhalation and following proper inhaler techniques.\n\nPrecautions and Warning\n\nBefore using BUDESHINE PLUS 400, consider the following precautions:\n\nInform your doctor if you have heart problems, glaucoma, diabetes, or kidney/liver conditions.\n\nAvoid use during acute asthma attacks; seek immediate medical help instead.\n\nPregnant or breastfeeding women should consult a healthcare provider before use.\n\nDo not stop or change dosage abruptly without medical advice, as it may worsen respiratory symptoms.\n\nStore in a cool, dry place and keep away from direct sunlight or heat sources.\n\nConclusion\n\nBUDESHINE PLUS 400 is a powerful and reliable inhalation therapy that combines anti-inflammatory, bronchodilator, and anticholinergic effects for comprehensive respiratory care. With consistent use, it helps manage asthma and COPD effectively, reduces exacerbations, and improves overall lung function. Trusted by healthcare professionals and manufactured under strict quality standards by Steris Healthcare, BUDESHINE PLUS 400 offers a balanced solution for long-term respiratory wellness.",
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"name": "Aspirin IP 75 mg, Atorvastatin Calcium IP 40 mg",
"description": "Introduction\n\nCardiovascular diseases remain one of the leading causes of illness and mortality worldwide, often developing silently over years before showing noticeable symptoms. Conditions such as heart attacks, strokes, and blocked arteries are frequently linked to two major factors: high cholesterol levels and abnormal blood clot formation. Managing these risks early and effectively is crucial for long-term heart health.\n\nATOVASTRIN AV 40/75 is a scientifically formulated combination medicine that brings together two well-established and widely trusted cardiovascular agents—Aspirin IP 75 mg and Atorvastatin Calcium IP 40 mg. This dual-action therapy is designed to protect the heart and blood vessels by addressing both clot formation and cholesterol management in a single tablet.\n\nBy combining these two essential medicines, ATOVASTRIN AV 40/75 simplifies treatment, improves patient compliance, and provides comprehensive cardiovascular protection for individuals at risk of heart-related complications.\n\nComposition\n\nEach film-coated tablet contains:\n\nAspirin IP 75 mg\n\nAtorvastatin Calcium IP equivalent to Atorvastatin 40 mg\n\nBrand Name: ATOVASTRIN AV 40/75\nDosage Form: Oral tablet\n\nHow ATOVASTRIN AV 40/75 Works\n\nATOVASTRIN AV 40/75 works through a complementary and synergistic mechanism, targeting two major contributors to cardiovascular disease.\n\nRole of Aspirin IP 75 mg\n\nAspirin at a low dose acts as an antiplatelet agent. It prevents platelets in the blood from sticking together and forming clots. Blood clots can block arteries supplying the heart or brain, leading to heart attacks or strokes. By reducing platelet aggregation, Aspirin helps maintain smooth blood flow.\n\nRole of Atorvastatin Calcium IP 40 mg\n\nAtorvastatin belongs to the statin class of medicines. It works by inhibiting an enzyme involved in cholesterol production in the liver. This results in:\n\nReduced levels of LDL (bad cholesterol)\n\nModerate increase in HDL (good cholesterol)\n\nLower triglyceride levels\n\nTogether, these effects slow the progression of plaque buildup in arteries and reduce the risk of cardiovascular events.\n\nUses of ATOVASTRIN AV 40/75\n1. Prevention of Heart Attack\n\nATOVASTRIN AV 40/75 is commonly prescribed to patients with a history of heart attack or those at high risk, helping prevent future cardiac events.\n\n2. Stroke Prevention\n\nBy preventing clot formation and improving lipid profiles, this combination reduces the risk of ischemic stroke, particularly in high-risk individuals.\n\n3. Management of High Cholesterol\n\nAtorvastatin effectively lowers cholesterol levels, especially LDL cholesterol, which is a major contributor to artery blockage.\n\n4. Post-Angioplasty or Bypass Care\n\nPatients who have undergone angioplasty, stent placement, or bypass surgery often receive this combination to prevent clot formation and recurrence of blockages.\n\n5. Coronary Artery Disease (CAD)\n\nATOVASTRIN AV 40/75 plays a key role in the long-term management of coronary artery disease by protecting blood vessels and improving circulation.\n\nKey Benefits of ATOVASTRIN AV 40/75\n1. Dual Cardiovascular Protection\n\nThis combination offers both antiplatelet and lipid-lowering effects, providing broad-spectrum heart protection in a single tablet.\n\n2. Reduces Risk of Blood Clots\n\nLow-dose Aspirin minimizes the chances of clot formation, ensuring uninterrupted blood flow to vital organs.\n\n3. Lowers Bad Cholesterol Levels\n\nAtorvastatin significantly reduces LDL cholesterol, which helps prevent plaque buildup in arteries.\n\n4. Slows Progression of Atherosclerosis\n\nBy improving cholesterol balance and preventing clots, the medicine slows the narrowing and hardening of arteries.\n\n5. Improves Treatment Compliance\n\nA single combination tablet reduces pill burden, making it easier for patients to follow long-term therapy.\n\n6. Suitable for Long-Term Use\n\nWhen taken under medical supervision, ATOVASTRIN AV 40/75 is effective and safe for extended use.\n\n7. Proven Clinical Ingredients\n\nBoth Aspirin and Atorvastatin are extensively researched and widely recommended in cardiovascular guidelines.\n\nDosage and Administration\n\nUsually taken once daily, preferably at the same time each day\n\nCan be taken with or after food to reduce stomach irritation\n\nSwallow the tablet whole with water; do not crush or chew\n\nThe exact dosage and duration depend on the patient’s medical condition, cholesterol levels, and risk factors, as determined by a healthcare professional.\n\nPossible Side Effects of ATOVASTRIN AV 40/75\n\nMost patients tolerate ATOVASTRIN AV 40/75 well. However, some side effects may occur.\n\nCommon Side Effects\n\nMild stomach pain\n\nNausea\n\nIndigestion\n\nHeadache\n\nMuscle aches\n\nLess Common Side Effects\n\nDizziness\n\nIncreased liver enzymes\n\nDiarrhea or constipation\n\nFatigue\n\nRare but Serious Side Effects\n\nGastrointestinal bleeding (associated with Aspirin)\n\nSevere muscle pain or weakness\n\nLiver function abnormalities\n\nAllergic reactions\n\nPatients are advised to report unusual muscle pain, dark urine, or persistent stomach discomfort to their doctor promptly.\n\nPrecautions and Warnings\n\nLiver Disease: Use cautiously in patients with liver disorders; regular liver function tests are recommended.\n\nBleeding Risk: Aspirin increases bleeding tendency; inform your doctor before surgery or dental procedures.\n\nAlcohol Intake: Excessive alcohol consumption should be avoided.\n\nPregnancy & Breastfeeding: Not recommended unless clearly prescribed by a doctor.\n\nDrug Interactions: Inform your physician about all other medications, including painkillers, anticoagulants, or herbal supplements.\n\nWho Should Avoid ATOVASTRIN AV 40/75?\n\nPatients with active liver disease\n\nIndividuals with bleeding disorders\n\nThose allergic to Aspirin or Atorvastatin\n\nPregnant women, unless advised by a physician\n\nStorage Instructions\n\nStore below 25°C\n\nProtect from moisture and direct sunlight\n\nKeep out of reach of children\n\nDo not use after the expiry date\n\nConclusion\nATOVASTRIN AV 40/75 (Aspirin IP 75 mg + Atorvastatin Calcium IP 40 mg) is a powerful and reliable combination therapy designed to address two of the most critical risk factors in cardiovascular disease—blood clot formation and high cholesterol levels. By offering comprehensive heart protection in a single tablet, it simplifies long-term treatment while enhancing patient compliance.",
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"name": "Rizatriptan Benzoate 5 mg",
"description": "Rizatriptan Benzoate 5 mg is a specialized medication widely used for the acute treatment of migraine headaches, including migraines with or without aura. It belongs to the triptan class of drugs, which work as selective serotonin receptor agonists targeting 5-HT1B and 5-HT1D receptors in the brain. By stimulating these receptors, rizatriptan benzoate helps to narrow dilated blood vessels in the brain and reduce inflammation, which are key contributors to migraine pain and associated symptoms.\n\nThe primary use of Rizatriptan Benzoate 5 mg is to relieve migraine attacks once they begin. It is clinically proven to reduce headache pain, sensitivity to light and sound, and other migraine-associated symptoms such as nausea and visual disturbances. This medication is effective in both adult patients and pediatric patients aged 6 to 17 years. It is important to note that rizatriptan is not indicated for the prevention of migraines or for the treatment of certain other types of headaches, such as cluster headaches or hemiplegic/basilar migraines.\n\nKey benefits of Rizatriptan Benzoate 5 mg include its rapid onset of action and targeted mechanism for migraine relief. Patients often experience significant headache improvement within 2 hours of taking the dose. The drug’s specificity for serotonin receptors in cerebral blood vessels helps minimize systemic side effects often seen with other pain medications. Rizatriptan’s effectiveness also extends to pediatric patients, providing migraine relief for children and adolescents, which is an important advantage in this age group.\n\nDespite its benefits, Rizatriptan Benzoate 5 mg may cause some side effects. Common side effects include dizziness, drowsiness, dry mouth, fatigue, and sensations of warmth or flushing. Some patients may also experience nausea or mild abdominal discomfort. These side effects are usually mild and transient. Serious side effects are rare but can include chest pain or tightness, irregular heartbeats, or signs of allergic reactions such as rash, swelling, or difficulty breathing. If any severe symptoms occur, immediate medical attention is necessary.\n\nPatients with certain cardiovascular conditions, uncontrolled high blood pressure, or ischemic heart disease should avoid rizatriptan due to its vasoconstrictive effects. Additionally, it should be avoided in patients using monoamine oxidase inhibitors (MAOIs) or other serotonergic drugs to prevent serious drug interactions.\nIn conclusion, Rizatriptan Benzoate 5 mg is an effective and targeted medication for the acute relief of migraine attacks in both adults and children. Its fast action and specific receptor targeting provide quick symptom relief with a relatively favorable safety profile when used as directed. Awareness of its potential side effects and contraindications ensures safe use under medical supervision, making rizatriptan a valuable option in migraine management.",
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"name": "Rifaximin oral suspension 100mg/5ml",
"description": "Rifaximin Oral Suspension 100 mg/5 ml is a broad-spectrum, gut-selective antibiotic formulated to treat various bacterial infections of the gastrointestinal tract, including traveler’s diarrhea, hepatic encephalopathy-related symptoms, and irritable bowel syndrome with diarrhea (IBS-D). Its unique non-systemic activity ensures that the drug acts locally in the intestines without significant absorption into the bloodstream, making it both effective and safe for long-term gastrointestinal management.\n\nDesigned in a pleasant-tasting, easy-to-administer oral suspension form, Rifaximin 100 mg/5 ml is especially suitable for pediatric patients and adults who have difficulty swallowing tablets. It is ideal for treating infections caused by non-invasive strains of Escherichia coli and other enteric bacteria, while also helping maintain intestinal balance and promoting recovery from gut-related complications.\nComposition\nEach 5 ml of suspension contains:\n\nRifaximin IP – 100 mg\n\nFlavored base and excipients – q.s.\n\nDosage Form: Oral Suspension\nAppearance: Pink to reddish suspension (depending on brand formulation)\nPackaging: Available in 30 ml, 60 ml, or 100 ml bottles with a measuring cup for accurate dosing.\n\nPharmacological Action and Mechanism\nRifaximin belongs to the rifamycin class of antibiotics and is structurally related to rifampicin. However, it has been specially modified to act locally in the gastrointestinal tract with negligible systemic absorption (<0.4%).\nMechanism of Action:\nRifaximin inhibits bacterial RNA synthesis by binding to the β-subunit of the bacterial DNA-dependent RNA polymerase.\nThis action prevents the transcription process, thereby stopping bacterial growth and replication.\nIts broad-spectrum activity covers both gram-positive and gram-negative bacteria, including aerobic and anaerobic strains.\nDue to poor absorption, it remains in the intestine at high concentrations, providing localized antibacterial effect without systemic toxicity.\n\nAdditionally, Rifaximin exerts eubiotic effects — it helps restore normal intestinal flora balance by selectively targeting harmful bacteria, which makes it useful for chronic intestinal disorders.\nUses and Indications\nRifaximin Oral Suspension 100 mg/5 ml is indicated for the following conditions:\n\nTraveler’s Diarrhea (TD):\n\nCaused by non-invasive strains of Escherichia coli.\nHelps relieve symptoms like watery stools, abdominal cramps, and bloating within a short duration.\nHepatic Encephalopathy (HE):\n\nUsed as adjunct therapy to reduce ammonia-producing gut bacteria, thereby lowering blood ammonia levels and improving mental status in patients with chronic liver disease.\n\nIrritable Bowel Syndrome with Diarrhea (IBS-D):\nProvides relief from abdominal pain, bloating, and irregular bowel movements by reducing bacterial overgrowth in the small intestine (SIBO).\nSmall Intestinal Bacterial Overgrowth (SIBO):\nHelps normalize gut flora and reduces gas, bloating, and discomfort caused by bacterial overgrowth.\nGastrointestinal Infections in Children:\nEffective in pediatric patients suffering from infectious diarrhea due to bacterial contamination of food or water.\n\nProphylactic Use:\nMay be prescribed post-surgery or in chronic liver disease to prevent recurrence of infection-related complications.\nDosage and Administration\nAdults and Children (>12 years): Usual dose is 10–20 ml (200–400 mg) every 8–12 hours, depending on the indication and physician’s recommendation.\nChildren (2–12 years): 5–10 ml (100–200 mg) two or three times daily, as directed by a pediatrician.\nShake the bottle well before each use.\nComplete the prescribed course even if symptoms improve early to prevent recurrence and antibiotic resistance.\nKey Benefits\nGut-Selective Action:\nActs locally within the intestine without entering systemic circulation, ensuring targeted therapy with minimal side effects.\n\nBroad-Spectrum Antibacterial Activity:\nEffective against a wide range of gram-positive, gram-negative, aerobic, and anaerobic enteric pathogens.\nSafe for Pediatric and Adult Use:\nThe liquid form allows accurate dosing and ease of administration, especially for children or elderly patients.\n\nMinimal Systemic Absorption:\nReduces the risk of systemic toxicity and drug interactions compared to conventional antibiotics.\nEffective for Traveler’s Diarrhea:\nRapidly controls diarrhea symptoms caused by E. coli and restores normal intestinal function.\nImproves Liver Health in Hepatic Encephalopathy:\nDecreases ammonia-producing bacteria, thereby reducing confusion, lethargy, and other symptoms related to hepatic encephalopathy.\n\nRestores Gut Microbiota Balance:\nHelps maintain healthy intestinal flora, supporting digestion and preventing recurrent infections.\n\nReduces Bloating and Abdominal Discomfort in IBS-D:\nProvides symptomatic relief and enhances quality of life in patients suffering from chronic bowel irregularities.\nLow Risk of Resistance:\nDue to its minimal absorption and targeted mechanism, the development of bacterial resistance is significantly lower.\nWell-Tolerated Formulation:\nThe oral suspension is gentle on the stomach and has a pleasant taste, improving compliance in children and adults alike.\n\nPrecautions and Warnings\n\nWhile Rifaximin Oral Suspension is considered safe for most patients, the following precautions should be observed:\n\nAllergy: Avoid use in patients with known hypersensitivity to rifaximin, rifampicin, or other rifamycin derivatives.\n\nSevere Diarrhea or Bloody Stool: If symptoms worsen or persist beyond 48 hours, consult a physician; may indicate an invasive infection requiring alternative therapy.\n\nLiver Impairment: Use with caution in patients with severe hepatic impairment; dosage adjustments may be required.\n\nPregnancy and Lactation: Limited data available; should be used only if clearly needed and prescribed by a doctor.\n\nLong-Term Use: Prolonged or unnecessary use may lead to superinfection by non-susceptible organisms, including fungi.\n\nDriving and Machinery: Generally safe, but dizziness or fatigue may occur in rare cases.\n\nPossible Side Effects\n\nRifaximin is generally well-tolerated due to its localized action in the gut. However, some mild to moderate side effects may occur in sensitive individuals.\n\nCommon Side Effects:\n\nNausea\n\nFlatulence (gas)\n\nAbdominal pain or cramping\n\nHeadache\n\nBloating\n\nConstipation\n\nLess Common / Rare Side Effects:\n\nSkin rash or itching\n\nDizziness or fatigue\n\nElevated liver enzymes (rare)\n\nVomiting or dry mouth\n\nFever or flu-like symptoms\n\nSerious Side Effects (Very Rare):\n\nAllergic reaction (rash, swelling, or breathing difficulty)\n\nPersistent watery or bloody diarrhea\n\nSevere abdominal pain\n\nIf any severe adverse reactions occur, discontinue use and seek medical attention immediately.\n\nStorage and Handling\n\nStore below 30°C in a cool, dry place.\n\nProtect from direct sunlight and freezing.\n\nShake well before use.\n\nKeep out of reach of children.\n\nDiscard any unused portion after the treatment course or expiry date.\n\nConclusion\n\nRifaximin Oral Suspension 100 mg/5 ml is a clinically trusted and patient-friendly antibiotic formulation for the treatment of gastrointestinal infections and liver-related complications. Its unique non-systemic mode of action, combined with broad antibacterial efficacy, makes it an excellent choice for both acute and chronic intestinal disorders.\n\nUnlike traditional antibiotics that circulate systemically, Rifaximin works locally within the intestines to eliminate harmful bacteria while preserving the natural gut flora. This results in faster relief from symptoms like diarrhea, bloating, and abdominal discomfort — with minimal side effects.\nWhether used for traveler’s diarrhea, hepatic encephalopathy, IBS-D, or bacterial overgrowth syndromes, Rifaximin offers targeted, safe, and effective therapy for restoring digestive health and improving overall well-being.",
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