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{ "products": [ { "_id": "6a86e496cc4491de1ed77dfd", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Etoricoxib & Cyclobenzaprine Hydrochloride Tablets", "description": "ERITOCOX BENZ 90/5 is a fixed-dose combination tablet pairing Etoricoxib 90 mg, a selective COX-2 anti-inflammatory, with Cyclobenzaprine Hydrochloride 5 mg, a centrally acting muscle relaxant. It is prescribed for short-term relief of acute musculoskeletal problems where pain, swelling, and muscle tightness occur together — think a sudden low-back strain, a stiff neck, or a flare-up of arthritis where the surrounding muscles clamp down defensively. Rather than treating the inflammation alone or the spasm alone, this tablet addresses both mechanisms in one dose, which can mean fewer pills and a more complete response for short, acute episodes. It is a prescription-only (Schedule H) medicine, produced under WHO-GMP and ISO-certified manufacturing standards by Steris Healthcare Pvt. Ltd. Typical side effects include drowsiness, dry mouth, and mild stomach upset; because the combination carries cardiovascular, gastrointestinal, and kidney considerations, it should only be used under a doctor's supervision. This page walks through what the tablet does, how it works, correct usage, safety information, and answers to the questions people most often ask.\n\nWhat Is ERITOCOX BENZ 90/5?\n\nPain from an acute back injury, a wrenched neck, or an arthritis episode almost never travels alone — it tends to bring a tense, guarded muscle along with it that makes every movement feel worse. ERITOCOX BENZ 90/5 was formulated with that pattern in mind, folding two separate mechanisms into a single tablet rather than requiring two prescriptions.\n\nActive Ingredient\tStrength\tRole\nEtoricoxib\t90 mg\tSelective COX-2 inhibitor for inflammatory pain\nCyclobenzaprine Hydrochloride\t5 mg\tCentrally acting skeletal muscle relaxant\n\nEach tablet is manufactured by Steris Healthcare Pvt. Ltd., a WHO-GMP and ISO-certified pharmaceutical company, so every batch meets verified potency and quality benchmarks.\n\nWhy This Combination Makes Sense\n\nMusculoskeletal pain is rarely a single-track problem. When tissue is injured or irritated, inflammation flares up locally — and nearby muscles frequently respond by tightening protectively. That protective tightening, the spasm, often becomes a pain generator of its own. Treat only the inflammation and the spasm can linger; treat only the spasm and the underlying inflammation keeps driving discomfort.\n\nERITOCOX BENZ 90/5 is built to intervene on both fronts at once:\n\nEtoricoxib addresses the chemical cascade responsible for pain and swelling at the injured site.\nCyclobenzaprine works through the central nervous system to calm the muscle guarding that so often rides alongside that pain.\nMechanism of Action: How ERITOCOX BENZ 90/5 Works\n\nEtoricoxib selectively inhibits the COX-2 enzyme — the enzyme the body ramps up at sites of tissue damage or irritation to manufacture prostaglandins, the chemical messengers behind pain, swelling, and localized heat. Because it targets COX-2 specifically rather than blocking both COX-1 and COX-2 the way older, non-selective NSAIDs do, etoricoxib is designed to control inflammatory pain while leaving more of the COX-1 activity that protects the stomach lining relatively undisturbed.\n\nCyclobenzaprine Hydrochloride takes a different route entirely — its primary site of action is the brainstem, not the muscle fiber itself. By dampening excessive motor signaling sent to skeletal muscle, it reduces spasm and stiffness without producing the broad muscle weakness that a directly-acting muscle agent might cause.\n\nPut together, the tablet delivers a two-pronged effect: peripheral anti-inflammatory action from etoricoxib, layered with central muscle relaxation from cyclobenzaprine.\n\n[Reviewer placeholder: insert verified pharmacokinetic data (onset, half-life, bioavailability) once confirmed by medical/regulatory team — do not publish unverified figures.]\n\nClinical Uses of ERITOCOX BENZ 90/5\n\nA physician may prescribe this combination for short-term management of acute conditions where pain, inflammation, and spasm show up together, including:\n\nCondition\tTypical Presentation\nAcute lower back pain\tPain with associated muscle guarding/spasm\nNeck strain / cervical spasm\tStiff, restricted neck movement\nSprains, strains, overuse injuries\tMusculoskeletal trauma with inflammatory pain\nOsteoarthritis flare-ups\tJoint pain accompanied by surrounding muscle tightness\nPostural or occupational muscle pain\tWork- or posture-related inflammation and tension\nMovement restriction linked to spasm\tReduced range of motion driven by muscular guarding\n\nSuitability for any of the above must be confirmed by a doctor based on your specific diagnosis and medical history.\n\nKey Benefits of ERITOCOX BENZ 90/5\nOne tablet, two mechanisms — anti-inflammatory pain relief and muscle-spasm relief combined, simplifying an otherwise two-drug regimen.\nSite-focused inflammation control — etoricoxib's COX-2 selectivity is intended to concentrate its effect where inflammation is actually active.\nA comparatively gentler GI footprint — COX-2-selective action is generally linked to lower gastrointestinal irritation risk than older non-selective NSAIDs, though vigilance is still warranted.\nLoosens spasm-related stiffness — cyclobenzaprine's central action helps release tight, guarded muscles restricting movement.\nAids functional recovery — easing both pain and spasm can make it more realistic to resume light activity, stretching, or physiotherapy once your doctor clears you.\nStreamlined short-course dosing — a once-daily schedule (as prescribed) cuts down pill burden versus taking an NSAID and a muscle relaxant separately.\nDosage & Administration\n\nThe following is general reference information — your doctor's specific prescription always takes precedence.\n\nTake ERITOCOX BENZ 90/5 exactly as prescribed, generally once a day, with or without food.\nSwallow the tablet whole with water; avoid crushing or chewing unless your doctor tells you otherwise.\nTreatment is typically short — anywhere from a few days to roughly two weeks — reflecting the acute, self-limiting nature of most pain-and-spasm episodes.\nIf a dose is missed, take it as soon as you remember, but skip it entirely if the next dose is nearly due. Never double up to make up for a missed dose.\nDo not extend the treatment period or adjust your dose independently, even if symptoms haven't fully resolved.\nSide Effects of ERITOCOX BENZ 90/5\nCommon Side Effects\nDrowsiness or sleepiness\nDizziness\nDry mouth\nHeadache\nStomach discomfort or indigestion\nNausea\nFatigue\nMild elevation in blood pressure in some individuals\nSerious Side Effects — Seek Medical Help Promptly\nSigns of gastrointestinal bleeding, such as black stools or vomiting blood\nA severe allergic reaction — swelling of the face or throat, breathing difficulty, or widespread rash\nChest pain, irregular heartbeat, or other symptoms suggestive of a cardiovascular event\nYellowing of the skin or eyes, which may point to liver involvement\nA noticeable drop in urine output, which may suggest kidney impairment\nSevere dizziness, confusion, or fainting\n\nIf any of these serious symptoms appear, stop the medicine and get medical attention immediately.\n\nPrecautions & Warnings\nShare your full medical history with your doctor before starting, including any heart, kidney, or liver conditions.\nUse cautiously — or avoid altogether — if you have a history of stomach ulcers or gastrointestinal bleeding.\nGenerally not advised for people with uncontrolled high blood pressure, existing heart disease, or a prior stroke, unless a doctor specifically clears its use.\nSteer clear of alcohol, since it can amplify cyclobenzaprine's sedative effect and add to gastrointestinal risk.\nCyclobenzaprine may cause drowsiness or dizziness — hold off on driving or operating machinery until you know how the tablet affects you.\nDon't combine ERITOCOX BENZ 90/5 with other NSAIDs, painkillers, or sedating medicines without checking with your doctor first.\nAvoid the medicine if you have known hypersensitivity to etoricoxib, cyclobenzaprine, or related compounds.\nNot generally recommended during pregnancy or breastfeeding unless a doctor specifically advises otherwise.\nAvoid combining with MAO inhibitors, or using shortly after stopping them.\nDrug Interactions to Flag With Your Doctor\n\nDisclose every prescription medicine, over-the-counter product, and supplement you take. Extra caution is needed around medicines affecting:\n\nBlood pressure regulation\nKidney function\nBlood clotting\nCentral nervous system activity (sedatives, other muscle relaxants)\nLiver metabolism\nOther anti-inflammatory or pain-relief medicines\nConclusion\n\nERITOCOX BENZ 90/5 brings Etoricoxib 90 mg and Cyclobenzaprine Hydrochloride 5 mg together to tackle a problem that rarely presents as a single issue — pain, inflammation, and muscle spasm that reinforce one another in acute musculoskeletal conditions. By acting on both the inflammatory and muscular sides of that cycle, it offers a more rounded short-term response than either ingredient could provide alone.\n\nGiven the genuine cardiovascular, gastrointestinal, kidney, and central-nervous-system considerations involved, ERITOCOX BENZ 90/5 is meant strictly for short, doctor-supervised courses — not casual or extended self-treatment. Always check with your doctor to confirm whether this combination is right for your condition, medical history, and current medications.\n\nPrescription only – consult your doctor.\n\nFrequently Asked Questions (Google & AI Mode / Voice Search Optimized)\n\n1. What is ERITOCOX BENZ 90/5 used for? It's typically prescribed for short-term relief of acute musculoskeletal issues — such as back pain, neck strain, or an arthritis flare-up — where pain, inflammation, and muscle spasm show up together.\n\n2. Is ERITOCOX BENZ 90/5 a muscle relaxant? It's a combination tablet: the muscle-relaxing effect comes from its Cyclobenzaprine Hydrochloride component, while Etoricoxib supplies the pain-relieving, anti-inflammatory action.\n\n3. Is Etoricoxib a strong painkiller? Etoricoxib is an effective selective COX-2 inhibitor typically used for moderate inflammation-related pain, such as arthritis or an acute musculoskeletal injury. Its appropriateness for your level of pain should be assessed by a doctor.\n\n4. Is Etoricoxib safe for the kidneys? As with other NSAIDs, etoricoxib can influence kidney function, particularly with extended use, higher doses, dehydration, or existing kidney disease. It should be used carefully and only under medical guidance if kidney health is a concern.\n\n5. Should ERITOCOX BENZ 90/5 be taken in the morning or at night? It's usually taken once a day at a time your doctor sets. Since cyclobenzaprine can cause drowsiness, many doctors lean toward an evening dose — but always stick to your specific prescription.\n\n6. What are the common side effects of ERITOCOX BENZ 90/5? Frequently reported effects include drowsiness, dizziness, dry mouth, headache, stomach discomfort, and mild fatigue. Most fade on their own, but persistent symptoms should be reported to your doctor.\n\n7. How fast does ERITOCOX BENZ 90/5 start working? Etoricoxib tends to absorb fairly quickly, and many people feel pain relief within roughly an hour, though onset can vary by individual and whether the tablet is taken with food.\n\n8. What should be avoided while on ERITOCOX BENZ 90/5? Skip alcohol, avoid taking other NSAIDs or painkillers without medical advice, and hold off on driving or operating machinery if you're feeling drowsy or dizzy.\n\n9. How many days can ERITOCOX BENZ 90/5 be taken? It's usually prescribed for a short stretch — a few days up to around two weeks — matching how acute conditions typically resolve. Anything longer needs your doctor's review.\n\n10. What are the benefits of ERITOCOX BENZ 90/5? It delivers combined relief from pain, inflammation, and muscle spasm in one tablet, which can make it easier to move normally and get back to daily activity sooner when used as directed.\n\n11. How safe is ERITOCOX BENZ 90/5? Taken exactly as prescribed and for the recommended duration, it's generally considered safe for most adults. It does carry cardiovascular, gastrointestinal, kidney, and liver-related risks that call for medical supervision, especially if you already have related conditions.\n\n12. Can ERITOCOX BENZ 90/5 be used for knee pain? Yes — its etoricoxib component is commonly used for joint pain tied to osteoarthritis or an acute injury, including the knee, by reducing the underlying inflammation. A doctor should confirm suitability first.\n\n13. Does ERITOCOX BENZ 90/5 cause drowsiness? Yes — drowsiness and dizziness are known effects linked to its cyclobenzaprine component. Avoid driving or tasks requiring full alertness until you know how it affects you.\n\n14. Can ERITOCOX BENZ 90/5 be bought without a prescription? No. This is a prescription-only medicine meant to be taken solely under a qualified doctor's supervision — it isn't meant for self-prescribing or extended use without medical oversight.\n\n15. Can ERITOCOX BENZ 90/5 be taken with food? It can generally be taken with or without food, though taking it with food may ease stomach discomfort for some people. Follow your doctor's specific instructions.\n\n16. Is ERITOCOX BENZ 90/5 habit-forming? Cyclobenzaprine isn't considered addictive with typical short-term use, but the tablet should still be taken only for the prescribed duration and not restarted on your own without medical advice.\n\n17. Who should avoid taking ERITOCOX BENZ 90/5? People with active stomach ulcers, significant heart, kidney, or liver disease, known hypersensitivity to NSAIDs, or those who are pregnant or breastfeeding should avoid it unless a doctor specifically clears its use.", "price": 222.0, "discountamount": 67.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2495, "imageuri": "https://productimages.withfloats.com/actual/6a86e4990f089c4695c57658.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a86e4990f089c4695c57658.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-08-20T11:27:18.403Z", "updatedon": "2026-08-20T11:27:18.403Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM/products/etoricoxib-cyclobenzaprine-hydrochloride-tablets/2495", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ERITOCOX BENZ 90/5", "category": "", "tags": [], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6a5092283075a19d4f2db6bd", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cyclosporine Eye Drops 0.05% w/v", "description": "Cyclosporine eye drops 0.05% are a prescription ophthalmic emulsion used to treat chronic dry eye disease (keratoconjunctivitis sicca) caused by ocular surface inflammation. Unlike lubricating tear substitutes that only manage symptoms, cyclosporine works as a calcineurin-inhibitor immunomodulator that calms the underlying inflammation suppressing your eyes' natural tear production. It is not a steroid. The standard dose is one drop in each affected eye, twice daily, about 12 hours apart, and visible improvement in tear production typically takes 6–12 weeks, with full benefit sometimes taking up to 3–6 months of consistent use. Common side effects include temporary burning, stinging, redness, and watery eyes at the time of instillation. It is a Schedule H prescription-only medicine in India and should be used only under a qualified ophthalmologist's guidance.\n\nWhat Is Cyclosporine Eye Drops 0.05%?\nCyclosporine eye drops 0.05% (ophthalmic emulsion) is a prescription formulation designed to manage chronic dry eye disease, a condition in which the eyes fail to produce enough tears or produce tears of poor quality, often because of an underlying inflammatory process on the ocular surface and in the lacrimal (tear-producing) gland.\nThis formulation is commonly prescribed for patients whose dry eye is presumed to be due to ocular inflammation — for example, those with moderate to severe dry eye, keratoconjunctivitis sicca, or dry eye associated with conditions like Sjögren's syndrome, that has not responded adequately to artificial tears alone.\nCyclosporine belongs to a class of drugs called calcineurin inhibitors. It differs fundamentally from corticosteroid eye drops, which suppress inflammation broadly and carry risks like raised intraocular pressure and cataract formation with long-term use. Cyclosporine instead selectively dampens the T-cell-mediated inflammatory response that is thought to suppress tear gland function, allowing the eye's own tear-producing mechanism to gradually recover.\n\nHow Do Cyclosporine Eye Drops Work? (Mechanism of Action)\n\nInflammation on the ocular surface – In chronic dry eye, T-lymphocytes infiltrate the conjunctiva and lacrimal gland, triggering a self-perpetuating inflammatory cycle.\nCalcineurin inhibition – Cyclosporine binds to a cellular protein (cyclophilin) and blocks calcineurin, an enzyme required to activate T-cells.\nReduced T-cell activation – With calcineurin blocked, T-cells cannot produce the inflammatory signals (such as interleukin-2) that damage the lacrimal gland and conjunctival tissue.\nRestoration of tear production – As local inflammation subsides over weeks to months, the lacrimal gland's ability to produce natural tears gradually improves.\nImproved tear film stability – With reduced inflammation and increased natural tear volume, patients typically notice less dryness, grittiness, and ocular surface damage over time.\n\nThis is why cyclosporine drops are described as disease-modifying for dry eye rather than purely symptomatic — they address a root inflammatory cause instead of simply lubricating the eye.\n\nClinical Indications\nIndicationDetailsChronic dry eye disease (keratoconjunctivitis sicca)Primary approved use; especially where tear production is suppressed due to ocular inflammationModerate to severe dry eye not controlled by artificial tearsSecond-line option when lubricants alone are insufficientDry eye associated with autoimmune conditionsE.g., Sjögren's syndrome-related dry eye, under specialist supervisionPost-refractive surgery dry eye (select cases)Sometimes used off-label under ophthalmologist guidance\n\nDosage & Administration\nParameterRecommendationStandard doseOne drop in each affected eye, twice dailyDosing intervalApproximately 12 hours apartContact lens useRemove lenses before instillation; wait at least 15 minutes before reinsertingOnset of noticeable effectUsually 6–12 weeksFull therapeutic benefitMay take up to 3–6 months of continuous useMissed doseContinue with next scheduled dose; do not double upDiscontinuationOnly under medical advice — symptoms may return if stopped prematurely\nNote: Cyclosporine eye drops are for long-term, continuous use as directed by your ophthalmologist. Improvement is gradual, not immediate, and consistent daily use is essential for benefit.\n\nKey Benefits\n\nTargets the underlying inflammatory cause of chronic dry eye rather than only masking symptoms\nCan increase natural tear production over sustained use\nGenerally well tolerated for long-term use, since it is not a steroid and does not carry steroid-related risks like elevated eye pressure or cataract with routine use\nMay reduce dependence on frequent artificial tear instillation over time\nSuitable for long-term maintenance therapy in chronic, relapsing dry eye disease\nCan improve comfort during visually demanding tasks (screen use, reading, driving) affected by chronic dryness\n\n\nPrecautions\n\nUse strictly as prescribed by an ophthalmologist; do not self-medicate\nNot intended for immediate relief of dry eye symptoms — artificial tears may be used concurrently for interim comfort as advised by your doctor\nShould not be used in the presence of an active ocular infection unless specifically directed by a physician\nInform your doctor if you are pregnant, breastfeeding, or have any known hypersensitivity to cyclosporine or emulsion components\nAvoid touching the dropper tip to the eye or any surface to prevent contamination\nIf wearing contact lenses, remove before application and reinsert only after 15 minutes\nDo not use expired or previously opened single-use vials, if applicable to your product format\nRegular ophthalmic follow-up is recommended to monitor treatment response\n\n\nSide Effects\nCommon (Usually Mild and Temporary)\n\nBurning or stinging sensation upon instillation\nEye redness\nWatery eyes (excessive tearing)\nEye discomfort or a feeling of something in the eye\nTemporary blurred vision immediately after application\n\nLess Common / Serious (Consult Your Doctor Promptly)\n\nPersistent or worsening eye pain\nSigns of eye infection (discharge, significant redness, swelling)\nVisual disturbance that does not resolve\nSigns of an allergic reaction (eyelid swelling, itching, rash)\n\nIf any serious or persistent symptom occurs, discontinue use and consult your ophthalmologist immediately.\n\nComparison: Cyclosporine Eye Drops vs. Other Dry Eye Treatments\nTreatmentMechanismOnset of ActionLong-Term Use ProfileCyclosporine 0.05% dropsCalcineurin inhibitor; reduces inflammation, restores natural tear productionWeeks to monthsGenerally suitable for continuous long-term useArtificial tears / lubricantsSymptomatic lubrication onlyImmediate, short-livedSafe but does not address inflammation; frequent reapplication neededCorticosteroid eye dropsBroad anti-inflammatory actionFast (days)Not recommended for long-term use due to risk of raised IOP, cataractLifitegrast ophthalmic solutionLFA-1 antagonist; blocks a different inflammatory pathwayWeeksAlternative option, mechanism differs from cyclosporine\n\nKey Statistics (Placeholder — Pending Clinical Reviewer Verification)\nMetricValueReported patients showing improved tear production at 6 months[Placeholder – insert verified clinical trial statistic]Prevalence of chronic dry eye disease in adults[Placeholder – insert epidemiological reference]Average time to symptomatic improvement[Placeholder – insert verified reference range]\nAll statistics above are placeholders and must be verified and populated by a qualified clinical reviewer prior to publication.\n\nExpert Insight\n\n[Placeholder — Expert quote pending. To be added only after review and approval by a licensed ophthalmologist/medical reviewer associated with Steris Healthcare. Do not fabricate or publish without sign-off.]\n\n\nPrice of Cyclosporine Eye Drops 0.05%\nThe price of cyclosporine eye drops 0.05% varies depending on pack size, brand, and region. For current pricing, availability, and prescription verification, please consult your ophthalmologist or authorized pharmacy.\nPrescription only – consult your doctor.\n\nConclusion\nCyclosporine eye drops 0.05% represent a meaningful shift in how chronic dry eye disease is managed — moving beyond temporary lubrication to address the underlying inflammatory process that suppresses natural tear production. For patients with moderate to severe dry eye that hasn't responded well to artificial tears alone, this calcineurin-inhibitor therapy offers a disease-modifying option that, with consistent long-term use, can meaningfully improve ocular comfort and tear film health. Because benefits build gradually over weeks to months, patience and adherence to the prescribed twice-daily regimen are essential. As with any prescription ophthalmic therapy, cyclosporine eye drops should only be used under the guidance of a qualified ophthalmologist, who can confirm suitability, monitor progress, and adjust care as needed.\n\nFrequently Asked Questions\n\n1. What are cyclosporine 0.05% eye drops used for?\nCyclosporine 0.05% eye drops are used to treat chronic dry eye disease caused by ocular surface inflammation. They help increase natural tear production in patients whose tear glands are suppressed due to inflammation, particularly when artificial tears alone aren't enough.\n\n2. How long can I use cyclosporine eye drops?\nCyclosporine eye drops are typically used long-term, as chronic dry eye is an ongoing condition. Many patients continue therapy for months to years under regular ophthalmologist supervision, since symptoms can return if the medication is stopped.\n\n3. Is Cyclomune a steroid?\nNo. Cyclomune (a brand of cyclosporine ophthalmic emulsion) is not a steroid. It is a calcineurin-inhibitor immunomodulator that works differently from steroid eye drops and does not carry the same risk of raised eye pressure or cataract associated with long-term steroid use.\n4. How quickly do cyclosporine eye drops start working?\nMost patients begin noticing improvement in tear production and dry eye symptoms within 6 to 12 weeks, though full benefit may take up to 3 to 6 months of consistent, twice-daily use.\n\n5. Can cyclosporine damage eyes?\nWhen used exactly as prescribed, cyclosporine eye drops are generally considered safe for long-term use. Temporary burning, stinging, or watering can occur at the time of instillation, but serious eye damage is uncommon. Any persistent pain, vision changes, or signs of infection should be reported to your ophthalmologist promptly.\n\n6. How much are cyclosporine 0.05% eye drops?\nPricing varies by brand, pack size, and region. Since this is a prescription-only medicine, please check current pricing with your prescribing doctor or a licensed pharmacy.\n\n7. Is cyclosporine a steroid?\nNo. Cyclosporine is a calcineurin inhibitor, a category of immunomodulating medication that is pharmacologically distinct from corticosteroids (steroids), even though both can reduce inflammation.\n\n8. Can I wear contact lenses while using cyclosporine eye drops?\nContact lenses should be removed before applying the drops and can typically be reinserted after about 15 minutes, unless your ophthalmologist gives different instructions.\n9. What happens if I stop using cyclosporine eye drops suddenly?\nStopping suddenly may cause dry eye symptoms to gradually return, since the underlying inflammation is no longer being managed. Always consult your doctor before discontinuing treatment.\n\n10. Can cyclosporine eye drops be used with artificial tears?\nYes, in many cases artificial tears can be used alongside cyclosporine drops for additional comfort, especially during the initial weeks before cyclosporine's full effect develops. Confirm timing and spacing with your doctor.\n\n11. Who should not use cyclosporine eye drops?\nPatients with known hypersensitivity to cyclosporine or its components, active untreated eye infections, or specific contraindications identified by their doctor should not use this medication without medical clearance.\n\n12. Are cyclosporine eye drops safe during pregnancy?\nUse during pregnancy or breastfeeding should only occur under medical supervision. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding before starting treatment.\n\n13. What is the difference between cyclosporine eye drops and lubricating eye drops?\nLubricating (artificial tear) drops provide temporary symptomatic relief by adding moisture to the eye, while cyclosporine drops target the underlying inflammation responsible for reduced natural tear production, offering a longer-term, disease-modifying approach.\n\n14. Can children use cyclosporine eye drops?\nUse in children should only be under the direct guidance and prescription of a pediatric ophthalmologist, based on individual clinical assessment.\n\n15. Do cyclosporine eye drops cause blurred vision?\nTemporary blurred vision can occur immediately after instillation in some patients. This usually resolves quickly. If blurred vision persists, consult your doctor.\n\n16. Can cyclosporine eye drops be used with other eye medications?\nOther eye medications, including other prescription drops, should only be combined with cyclosporine under your ophthalmologist's guidance, with appropriate spacing between different drops.\n\n17. Why do cyclosporine eye drops take so long to work?\nBecause cyclosporine works by gradually reducing chronic inflammation in the lacrimal gland and ocular surface rather than providing instant lubrication, visible improvement in natural tear production takes weeks to months rather than being immediate.", "price": 495.0, "discountamount": 149.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2468, "imageuri": "https://productimages.withfloats.com/actual/6a50922a464ced2a630398a1.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a50922a464ced2a630398a1.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2026-07-10T06:33:12.096Z", "updatedon": "2026-07-10T06:33:12.096Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//cyclosporine-eye-drops-0-05-w-v/2468", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CIPVISION CYCLOPURE 0.5 mg", "category": "Opthalmology Range", "tags": [ "Cyclosporine Eye Drops 0.05% w/v", "cyclosporine eye drops", "cyclosporine eye drops uses", "cyclosporine eye drops ip 0.05 w/v", "cyclosporine eye drops price", "cyclosporine eye drops uses in hindi", "cyclosporine eye drops side effects", "cyclosporine eye drops 0.05", "cyclosporine eye drops brand name", "cyclosporine eye drops india" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "6948f4ee5837f90c86a7e578", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Elagolix 200mg ", "description": "Eligolux200 contains 200 mg of elagolix per tablet and is manufactured by Steris Healthcare Pvt Ltd in India as a prescription medication in packs of 3x10 tablets. Elagolix acts as a potent gonadotropin-releasing hormone (GnRH) receptor antagonist, binding competitively to GnRH receptors in the pituitary gland to rapidly reduce estrogen and progesterone levels without the initial flare-\nup seen in agonists. This mechanism starves endometrial-like tissue outside the uterus of hormonal stimulation, shrinking lesions and easing inflammation.\n\nAdminister Eligolux200 orally, swallowed whole with water, with or without food, typically starting within 7 days of menstrual onset. Standard dosing for severe cases involves 200mg twice daily for up to 6 months, or 150mg once daily extended to 24 months, adjusted by physicians based on tolerance and response. Store in a cool, dry place away from moisture and light, keeping out of children's reach.\n\nPrimary Uses\nEligolux200 targets moderate to severe endometriosis-associated pain, including dysmenorrhea (painful periods), nonmenstrual pelvic pain, and dyspareunia (painful intercourse). Endometriosis affects millions globally, causing tissue similar to the uterine lining to grow ectopically, leading to chronic inflammation, adhesions, and scarring. By dosing flexibly, Eligolux200 suits patients needing stronger suppression for intense symptoms, reducing reliance on opioids or surgery.\n\nClinical trials like Elaris EM-I and EM-II showed 75% dysmenorrhea reduction and 50-60% nonmenstrual pain relief at 6-12 months. It also curbs heavy menstrual bleeding in uterine fibroids, offering dual benefits for overlapping conditions. Physicians prescribe it when first-line NSAIDs or oral contraceptives fail, prioritizing non-invasive symptom control.\n​\n\nKey Benefits\nEligolix in Eligolux200 delivers rapid pain relief, with significant improvements in daily pain scales within 3 months versus placebo. Women report 47% better composite pelvic pain scores, enhancing daily activities, work productivity, and intimacy. Quality-of-life metrics improve consistently over 24 weeks, including reduced fatigue and better emotional well-being.\n​\n\nUnlike injectables, its oral form and dose-dependent estrogen suppression allow titration—lower doses minimize hypoestrogenic effects while higher 200mg dosing tackles severe pain. Studies confirm amenorrhea in 25% of users early on, slashing bleeding days by up to 50%. Long-term data up to 12 months with add-back therapy sustains efficacy, preserving bone health better than monotherapy. Patients regain control, avoiding invasive laparoscopies and reclaiming normalcy.\n​\n\nBenefit\tEvidence from Trials'\tImpact on Patients\nDysmenorrhea Reduction:\t75% at 6 months \n​\tFewer missed workdays\nNonmenstrual Pain Relief:\t50-60% improvement \n​\tEnhanced mobility\nBleeding Control:\t14% bleeding days vs. 24% baseline \n​\tImproved hygiene, anemia prevention\nQuality of Life\tSustained over 24 weeks \n​\tBetter sleep, relationships\nPotential Side Effects\nCommon side effects of Eligolux200 mirror hypoestrogenic states: hot flashes, night sweats, headache, and nausea, each affecting about 10% of users. These often lessen as the body adjusts, with 69.5% overall adverse event rate over 24 weeks, mostly mild. Mood changes like irritability or depression occur less commonly, warranting mood monitoring.\n​\n\nBone mineral density (BMD) loss poses a key concern—200mg twice daily causes -1.5% to -2.4% drops at lumbar spine and hip after 6 months, attenuated with calcium/vitamin D or add-back therapy. Rare serious risks include suicidal thoughts, liver enzyme elevations, or allergic reactions like anaphylaxis. Discontinuation due to events stays low at 4-12%. No deaths are linked directly to treatment in trials.\n​\n\nSide Effect Category\tFrequency\tManagement\nVasomotor (Hot Flashes)\t9.9-10% \n​\tLifestyle cooling, dose adjustment\nNeurologic (Headache)\t9.9% \n​\tHydration, analgesics\nBone Loss\tUp to 2.4% at 6 months \n​\tDEXA scans, supplements\nMood Changes\tLess common \n​\tPsychiatric screening\nPrecautions and Contraindications\nAvoid Eligolux200 in pregnancy (risk of early loss), known osteoporosis, severe hepatic impairment, or with strong OATP1B1 inhibitors like cyclosporine or gemfibrozil. Women of childbearing age need effective non-hormonal contraception during and 28 days post-therapy, as it impairs recognition of pregnancy via amenorrhea. Not for pediatrics under 18 or geriatrics lacking data.\n\nScreen for depression history, liver function, and BMD before starting; monitor quarterly. Drug interactions abound with rifampin (reduces levels) or over 50 others like clarithromycin—inform physicians fully. Breastfeeding lacks safety data; weigh risks. Regular blood/urine tests track efficacy and safety.\n​\n\nDosage Guidelines\nInitiate Eligolux200 at 150mg daily for milder cases, escalating to 200mg BID for dyspareunia or severe pain, max 6 months at higher dose. Miss a dose? Take promptly unless near the next; never double. Duration caps at 24 months total, with liver-adjusted lower dosing. Pair with add-back for extended use to curb BMD loss.\n​\n\nPhysicians tailor based on response: 74-77% complete 6-month trials. Swallow intact; no crushing.\n​\n\nClinical Evidence\nPhase III trials (Elaris EM-I/II) randomized 1689 women, proving both doses superior to placebo for co-primary endpoints of dysmenorrhea and nonmenstrual pain. Open-label extensions to 24 weeks maintained gains. A 12-month study with add-back showed persistent relief and <1% additional BMD loss versus placebo. Real-world use echoes this, positioning Eligolix as first oral GnRH antagonist approved for endometriosis.\n​\n\nVersus relugolix, Eligolix offers comparable pelvic pain reduction with adjustable dosing. Indian brands like Eligolux200 align with global standards.\n​\n\nConclusion\nEligolux200 transforms endometriosis management, delivering substantial pain relief and functional gains through precise hormonal control. Balancing robust benefits against manageable risks like BMD monitoring empowers women toward symptom-free lives. Consult healthcare providers for personalized integration into care plans.\n", "price": 1000.0, "discountamount": 300.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2251, "imageuri": "https://productimages.withfloats.com/actual/694a2b9f403179ac7e958ef6.png", "tileimageuri": "https://productimages.withfloats.com/tile/694a2b9f403179ac7e958ef6.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-12-22T07:36:14.316Z", "updatedon": "2026-03-26T06:00:31.59Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//elagolix-200mg-/2251", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ELIGOLUX 200", "category": "GYANECOLOGYRANGE", "tags": [ "Elagolix Tablets 200mg", "Elagolix acts as a potent gonadotropin-releasing hormone.", "nonmenstrual pelvic pain.", "adhesions, and scarring", "preserving bone health better than monotherapy.", "avoiding invasive laparoscopies and reclaiming normalcy.", "pituitary gland to rapidly reduce estrogen and progesterone.", "tab elagolix 200mg", "elagolix 200mg.", "elagolix.", "elagolix 200.", "elagolix tablets", "elagolix tablets uses.", "elagolix 200 mg price.", "elagolix mechanism of action.", "elagolix 200 mg uses.", "tab elagolixtab elagolix." ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.0, "isnotforsale": false }, { "_id": "68bc22e83c3803d861d696a9", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Cefpodoxime Proxetil Tablets IP 200 mg", "description": "CEPHODOXIAA 200 is a broad-spectrum oral antibiotic from Steris Healthcare Pvt. Ltd., containing Cefpodoxime Proxetil 200 mg. It belongs to the third-generation cephalosporin class, designed to combat a wide range of bacterial infections effectively. With its high bioavailability, safety profile, and proven efficacy, it is trusted in clinical practice for managing both respiratory and urinary tract infections.\nUsage and Benefits\nCEPHODOXIAA 200 is prescribed for the treatment of bacterial infections caused by susceptible microorganisms, including:\n\nRespiratory tract infections (bronchitis, pneumonia, sinusitis, pharyngitis, tonsillitis)\n\nUrinary tract infections (cystitis, pyelonephritis)\n\nEar infections (otitis media)\n\nSkin and soft tissue infections\n\nCertain sexually transmitted infections (like gonorrhea)\n\nCommunity-acquired infections where cephalosporins are indicated\n\nBenefits:\n\nBroad-spectrum antibacterial activity against gram-positive and gram-negative organisms\n\nHigh tolerability and oral bioavailability\n\nConvenient twice-daily dosing\n\nEffective alternative when resistance to other antibiotics is suspected\n\nDosage and Administration\nAdults: Typical dose is 200 mg every 12 hours, depending on the severity of the infection.\n\nChildren: Dose is weight-adjusted, usually prescribed in suspension form.\n\nDuration: Treatment typically lasts 5–14 days depending on the infection type and clinical response.\n\nAdministration Tips:\n\nTake with food to enhance absorption.\n\nComplete the full course even if symptoms improve early.\n\nDo not double the dose if a dose is missed—take it as soon as remembered unless it is nearly time for the next dose.\n\nSide Effects\nLike all medicines, CEPHODOXIAA 200 may cause mild to moderate side effects. Common ones include:\n\nGastrointestinal upset (nausea, diarrhea, abdominal pain)\n\nHeadache or dizziness\n\nSkin rash or itching\n\nRare but serious side effects:\n\nSevere allergic reactions (swelling, difficulty breathing)\n\nPseudomembranous colitis (persistent diarrhea)\n\nLiver enzyme elevations\n\nDrug Interactions\nAntacids & H2 blockers: May reduce absorption of Cefpodoxime. Take at least 2–3 hours apart.\n\nBlood thinners (e.g., warfarin): May increase risk of bleeding.\n\nOther antibiotics: Avoid concurrent use unless directed by a doctor to prevent resistance.\n\nAlways inform your physician of all medications and supplements you are taking before starting therapy.\n\nConclusion\nCEPHODOXIAA 200 (Cefpodoxime Proxetil 200 mg) from Steris Healthcare Pvt. Ltd. is a reliable, broad-spectrum antibiotic used in the management of common bacterial infections. With its excellent safety profile, ease of oral administration, and clinical efficacy, it remains a preferred choice for doctors worldwide. Patients should adhere strictly to prescribed dosage and complete the treatment course to ensure optimal results and prevent antibiotic resistance.", "price": 173.0, "discountamount": 52.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 1, "_keywords": null, "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 2173, "imageuri": "https://productimages.withfloats.com/actual/69294e18b456de02c99ff75f.png", "tileimageuri": "https://productimages.withfloats.com/tile/69294e18b456de02c99ff75f.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2025-09-06T12:02:48.098Z", "updatedon": "2026-05-25T06:48:30.738Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//cefpodoxime-proxetil-tablets-ip-200-mg/2173", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "CEPHODOXIAA 200", "category": "GENERAL RANGE", "tags": [ "Cefpodoxime Proxetil 200 mg", "urinary tract infections", "Cefpodoxime Proxetil Tablets IP 200 mg", "Buy Cefpodoxime Proxetil 200 mg Tablets Online", "Cefpodoxime Proxetil 200 mg Antibiotic Tablets", "Cefpodoxime 200 mg Tablets for Bacterial Infection", "Cefpodoxime Proxetil IP 200 mg Medicine", "Broad Spectrum Antibiotic Cefpodoxime Tablets", "Cefpodoxime Proxetil Tablets for Respiratory Infections", "Cefpodoxime Proxetil 200 mg Product Image", "Best Antibiotic Tablets for Bacterial Infection", "Prescription Antibiotic Medicine Cefpodoxime 200 mg", "Cefpodoxime Tablets for Throat and Chest Infection", "Cefpodoxime Proxetil Tablets for UTI Treatment", "Buy Cefpodoxime Antibiotic Tablets Online", "Cefpodoxime Proxetil Tablets for Infection Treatment", "cefpodoxime proxetil tablets uses", "cefpodoxime proxetil tablets", "cefpodoxime proxetil tablets ip 200 mg uses in hindi", "cefpodoxime proxetil tablets ip 200 mg", "cefpodoxime proxetil tablets ip", "cefpodoxime proxetil tablets ip 200 mg uses", "cefpodoxime proxetil tablets ip uses in hindi", "what is the use of cefpodoxime proxetil tablets", "cefpodoxime proxetil tablets ip 200 mg price", "cefpodoxime proxetil tablets 200mg" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": null, "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "666ad3a59b27ca0f04a6c9e6", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Pramipexole 0.125mg", "description": "Introduction to Pramipexole 0.125mg\n\nPramipexole 0.125mg is a prescription medicine widely used for the treatment of Parkinson’s disease and Restless Legs Syndrome (RLS). It belongs to a class of medicines known as dopamine agonists, which work by stimulating dopamine receptors in the brain. Dopamine is a natural chemical responsible for controlling movement, coordination, and nerve signaling.\n\nPatients suffering from shaking, stiffness, muscle spasms, involuntary movements, or uncomfortable sensations in the legs often benefit from this medicine. Pramipexole 0.125mg is commonly recommended by neurologists because it helps improve motor control and enhances quality of life.\n\nThis low-dose strength is usually prescribed during the initial stages of treatment to help the body adjust gradually while minimizing side effects.\n\nWhat is Pramipexole 0.125mg Used For?\n\nPramipexole 0.125mg tablets are mainly prescribed for:\n\n1. Parkinson’s Disease\n\nParkinson’s disease is a progressive neurological disorder that affects movement and muscle control. Patients may experience:\n\nTremors\nMuscle stiffness\nSlow body movements\nBalance issues\nDifficulty walking\nCoordination problems\n\nPramipexole helps stimulate dopamine activity in the brain, improving these symptoms effectively.\n\n2. Restless Legs Syndrome (RLS)\n\nRestless Legs Syndrome causes uncomfortable sensations in the legs and an uncontrollable urge to move them, especially during nighttime. Symptoms may include:\n\nTingling sensation\nBurning feeling\nCrawling discomfort\nLeg twitching\nSleep disturbances\n\nPramipexole 0.125mg helps calm nerve activity and provides relief from discomfort and sleep interruptions.\n\nHow Does Pramipexole 0.125mg Work?\n\nPramipexole acts by mimicking dopamine, a neurotransmitter naturally present in the brain. In conditions like Parkinson’s disease, dopamine levels decrease significantly, leading to movement-related disorders.\n\nThe medicine binds to dopamine receptors and activates them, helping restore proper communication between nerves and muscles.\n\nf(x)=Dopamine Receptor Activation\n\nThis action improves:\n\nBody movement\nMuscle coordination\nControl over tremors\nWalking ability\nSleep quality in RLS patients\nBenefits of Pramipexole 0.125mg\nImproves Motor Function\n\nThe medicine helps reduce tremors, stiffness, and muscle rigidity associated with Parkinson’s disease.\n\nReduces Leg Discomfort\n\nPatients suffering from Restless Legs Syndrome often experience significant symptom relief.\n\nEnhances Sleep Quality\n\nBy reducing nighttime leg movement and discomfort, the medicine promotes better sleep.\n\nBetter Daily Functioning\n\nImproved mobility and muscle control help patients perform daily activities more comfortably.\n\nGradual & Controlled Therapy\n\nThe 0.125mg dosage is suitable for initiating treatment safely with lower risk of side effects.\n\nDosage and Administration\n\nPramipexole 0.125mg should always be taken exactly as prescribed by a healthcare professional.\n\nGeneral Guidelines\nTake the tablet with water.\nIt can be taken with or without food.\nTry to take it at the same time every day.\nDo not crush or chew the tablet unless advised.\nFor Parkinson’s Disease\n\nDoctors usually begin treatment with a low dose like 0.125mg and gradually increase it depending on patient response.\n\nFor Restless Legs Syndrome\n\nThe medicine is generally taken 2–3 hours before bedtime for optimal results.\n\nDo not stop taking the medicine suddenly, as abrupt discontinuation may worsen symptoms.\n\nPossible Side Effects of Pramipexole 0.125mg\n\nLike all medicines, Pramipexole may cause some side effects. Most are mild and temporary.\n\nCommon Side Effects\nNausea\nDizziness\nSleepiness\nFatigue\nDry mouth\nConstipation\nHeadache\nLess Common Side Effects\nHallucinations\nConfusion\nLow blood pressure\nSwelling in legs\nSudden sleep episodes\nAbnormal dreams\nSerious Side Effects\n\nSeek immediate medical attention if you experience:\n\nSevere allergic reactions\nBreathing difficulty\nChest pain\nUnusual behavior changes\nFainting episodes\nPrecautions Before Using Pramipexole 0.125mg\n\nBefore taking this medicine, inform your doctor if you have:\n\nKidney disease\nHeart problems\nMental health disorders\nLow blood pressure\nSleep disorders\nHistory of hallucinations\nPregnancy & Breastfeeding\n\nUse during pregnancy or breastfeeding only if prescribed by a doctor.\n\nDriving Warning\n\nPramipexole may cause drowsiness or sudden sleep attacks. Avoid driving or operating machinery until you know how the medicine affects you.\n\nAlcohol Interaction\n\nAlcohol may increase dizziness and drowsiness caused by the medicine.\n\nDrug Interactions\n\nPramipexole 0.125mg may interact with certain medicines, including:\n\nSedatives\nSleeping pills\nAntipsychotic medicines\nBlood pressure medications\nAntidepressants\n\nAlways inform your doctor about all prescription medicines, supplements, and herbal products you are using.\n\nWho Should Avoid Pramipexole 0.125mg?\n\nThis medicine may not be suitable for:\n\nPatients allergic to pramipexole\nIndividuals with severe kidney impairment\nPatients with uncontrolled psychiatric conditions\nPeople prone to excessive daytime sleepiness\n\nMedical consultation is essential before starting therapy.\n\nStorage Instructions\n\nStore Pramipexole 0.125mg tablets:\n\nIn a cool and dry place\nAway from direct sunlight\nBelow recommended room temperature\nOut of reach of children and pets\n\nDo not use expired medicine.\n\nWhy Buy Pramipexole 0.125mg Online?\n\nBuying medicines online offers convenience, affordability, and easy access to prescription medicines.\n\nAdvantages Include:\nEasy home delivery\nCompetitive pricing\nGenuine medicines\nTime-saving ordering process\nAvailability of multiple strengths\n\nAlways purchase medicines from trusted pharmaceutical suppliers and licensed online pharmacies.\n\nFrequently Asked Questions (FAQs)\nIs Pramipexole 0.125mg habit-forming?\n\nNo, the medicine is generally not considered habit-forming when used as prescribed.\n\nHow long does Pramipexole take to work?\n\nSome patients notice improvement within a few days, while full benefits may take several weeks.\n\nCan I take Pramipexole daily?\n\nYes, it is commonly prescribed for regular daily use under medical supervision.\n\nDoes Pramipexole cure Parkinson’s disease?\n\nNo, it does not cure Parkinson’s disease, but it helps manage symptoms effectively.\n\nCan elderly patients use this medicine?\n\nYes, but dosage adjustments may be required based on kidney function and overall health.\n\nConclusion\n\nPramipexole 0.125mg is an effective treatment option for managing symptoms of Parkinson’s disease and Restless Legs Syndrome. By improving dopamine activity in the brain, the medicine helps reduce tremors, stiffness, discomfort, and sleep disturbances.\n\nThe low-dose 0.125mg strength is particularly useful for initiating therapy gradually and safely. When taken under proper medical supervision, Pramipexole can significantly improve mobility, comfort, and overall quality of life.", "price": 54.0, "discountamount": 16.2, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "day", "RLS", "life", "food", "brain", "EMAIL", "Order", "water", "tablet", "0.5 mg", "1.5 mg", "quality", "tremors", "bedtime", "Research", "patients", "Benefits", "symptoms", "response", "same time", "Parkinson", "PRAMIXOLE", "next dose", "treatment", "stiffness", "conditions", "double dose", "three doses", "progression", "bloodstream", "information", "Pramipexole", "coordination", "sterispharma", "sterisonline", "Key Features", "Introduction", "CALL/WHATSAPP", "slow movement", "Administration", "Initial Dosage", "Flexible Dosing", "0.125 mg dosage", "regular schedule", "individual needs", "dopamine agonist", "maintenance dose", "movement control", "dopamine receptors", "Disease Management", "Maintenance Dosage", "significant relief", "precise adjustments", "typical starting dose", "Improved Motor Function", "neuroprotective effects", "uncomfortable sensations", "Neuroprotective Properties", "consistent medication levels", "Restless Legs Syndrome Relief" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1874, "imageuri": "https://productimages.withfloats.com/actual/6a100076d56634bf5bbe9d67.png", "tileimageuri": "https://productimages.withfloats.com/tile/6a100076d56634bf5bbe9d67.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-13T11:10:29.979Z", "updatedon": "2026-05-22T07:06:29.602Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//pramipexole-0-125mg/1874", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "PIMAPEXOLE 0.125", "category": "NEUROLOGY RANGE", "tags": [ "side effects of pramipexole 0.125mg", "pramipexole 0.125 mg dosage", "pramipexole restless legs dose", "side effects of pramipex 0.25", "pramipexole 0.125mg tablet use in hindi", "pramipexole 0.125mg tablets", "pramipexole 0.125mg", "side effects of pramipexole 0.125mg", "Pramipexole 0.125 mg Tablets", "Buy Pramipexole 0.125 mg Tablets Online", "Restless Legs Syndrome Medicine Pramipexole", "Pramipexole 0.125 mg Neurological Medicine", "Pramipexole 0.125 mg Product Image", "Neurology Medicine Pramipexole 0.125 mg" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "6662e3b87247ae19c482b97c", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "Enzalutamide 40mg", "description": "Enzalutamide 40 mg capsules represent a breakthrough in targeted therapy for advanced prostate cancer, particularly in metastatic castration-resistant prostate cancer (mCRPC) and metastatic castration-sensitive prostate cancer (mCSPC). This second-generation androgen receptor inhibitor works by disrupting multiple steps in the androgen signaling pathway, offering patients a chance to slow disease progression, reduce tumor burden, and extend survival even after other treatments fail. Administered as a once-daily oral capsule, enzalutamide 40 mg provides four capsules per day (total 160 mg), making it convenient for long-term use in clinical settings where hormone therapy alone proves insufficient.​\n\nPatients often turn to enzalutamide when facing rising PSA levels despite androgen deprivation therapy (ADT), experiencing bone pain, or dealing with cancer spread to lymph nodes or distant sites. Its high affinity for androgen receptors—5-8 times stronger than first-generation antiandrogens like bicalutamide—ensures potent blockade without agonist activity, translating to real-world benefits like delayed chemotherapy needs and improved quality of life during treatment.​\n\nProduct Use and Indications\nEnzalutamide 40 mg primarily treats metastatic castration-resistant prostate cancer (mCRPC) in patients previously treated with docetaxel or progressing despite ADT. The FDA and EMA approvals extend to non-metastatic CRPC (nmCRPC) with high-risk biochemical recurrence and metastatic castration-sensitive prostate cancer (mCSPC) alongside ADT, based on landmark trials like AFFIRM, PREVAIL, PROSPER, and ARCHES.​\n\nKey uses include:\n\nSlowing tumor growth in hormone-refractory stages by inhibiting androgen-driven proliferation.\n\nReducing skeletal-related events like fractures or spinal cord compression in bone metastases.\n\nDelaying progression to chemotherapy in pre-chemotherapy mCRPC, with PREVAIL showing 17-month median radiographic progression-free survival (rPFS) versus 4 months for placebo.​\n\nIn mCSPC, ARCHES trial data demonstrated 61% risk reduction in progression or death when combined with ADT. Clinicians monitor PSA response (≥50% decline in 70-80% of patients) and imaging every 3 months to assess efficacy.​\n\nMechanism of Action\nEnzalutamide 40 mg exerts a threefold blockade on androgen receptor (AR) signaling: it competitively inhibits androgen binding to AR (with affinity rivaling dihydrotestosterone), prevents nuclear translocation of the ligand-receptor complex, and disrupts DNA binding and coactivator recruitment at androgen response elements. This comprehensive inhibition downregulates oncogenes like TMPRSS2-ERG fusion genes common in prostate cancer, inducing apoptosis and halting cell proliferation without lowering systemic testosterone levels.​\n\nUnlike earlier antiandrogens, enzalutamide avoids partial agonist effects, ensuring pure antagonism even in AR-overexpressing tumors. Its active metabolite, N-desmethyl enzalutamide (via CYP2C8), contributes 30% to activity, with steady-state levels achieved in 4 weeks.​\n\nKey Benefits\nExtended Progression-Free Survival: In PREVAIL (pre-chemo mCRPC), median overall survival reached 32.4 months versus 30.2 for placebo; PROSPER (nmCRPC) delayed metastasis by 22 months.​\n\nPSA Response and Tumor Shrinkage: 78% PSA90 response rate; radiographic responses in 29% with measurable disease.​\n\nQuality of Life Preservation: Delays pain progression (hazard ratio 0.40) and chemotherapy (by 17 months), maintaining daily function.​\n\nBone Protection: Reduces fractures by 30% in high-risk patients via AR inhibition in osteoblasts.​\n\nCombination Synergy: Enhances ADT efficacy in mCSPC, cutting death risk by 33% per ARCHES.​\n\nThese benefits position enzalutamide 40 mg as a cornerstone in modern prostate cancer protocols, especially for fit patients tolerating oral therapy.​\n\nSide Effects\nEnzalutamide 40 mg carries a manageable profile, with most effects dose-related and reversible upon discontinuation.\n\nCommon Side Effects\nFatigue/Asthenia (34-50%): Often mild, peaking in first months; rest and nutrition help.\n\nArthralgia/Myalgia (14-21%): Joint/muscle pain managed with NSAIDs.\n\nHot Flashes (20%): Androgen blockade mimic; hydration aids.\n\nHeadache/Dizziness (12-19%): Transient; avoid driving if severe.\n\nHypertension (6-13%): Monitor BP monthly; antihypertensives as needed.\n\nGI Issues (diarrhea 12%, nausea 11%): Antiemetics support compliance.​\n\nSerious Side Effects\nSeizures (0.9%): Highest risk in epileptics or brain mets; EEG baseline, avoid triggers.\n\nPosterior Reversible Encephalopathy (PRES): Rare (<0.1%); headache, confusion—MRI confirms.\n\nFalls/Fractures (15% increased risk): Due to weakness/falls; DEXA scans recommended.\n\nCardiac Events (2-5%): MI/arrhythmias; ECG monitoring in CVD history.\n\nHepatic Injury (1%): ALT/AST elevation; monthly labs first 3 months.​\n\nDiscontinuation occurs in 8-10%; supportive care mitigates most.​\n\nDosage and Administration\nStandard dose: 160 mg (four 40 mg capsules) once daily, with or without food. Swallow intact; no crushing. Adjust for CYP2A4 inducers (e.g., rifampin—increase to 240 mg) or strong inhibitors (reduce to 80 mg). Continue until progression/toxicity; no dose interruptions beyond 28 days without reassessment.​\n\nPrecautions and Monitoring\nContraindicated in pregnancy (teratogenic; absolute contraception for men/ partners). Screen for seizure history; CYP2C8/3A4 interactions (e.g., ketoconazole). Baseline LFTs, PSA, testosterone; imaging q8-12 weeks. Elderly (>75) monitor falls.​\nConclusion\nEnzalutamide 40 mg stands as a transformative therapy, empowering prostate cancer patients with prolonged control over aggressive disease through precise AR inhibition. Balancing robust efficacy—evidenced by landmark trials delaying metastasis and death—with proactive side effect management, it enhances survival and daily living. Patients achieve meaningful milestones, from family events to travel, underscoring its role in personalized oncology. Consult oncologists for integration into care plans, ensuring optimal outcomes in this challenging journey.\nEmail: info@sterispharma.com / contact@sterispharma.com\nCall/WhatsApp: 7877551268, 7849827488\n\n\n\n\n\n\n\n\n", "price": 10781.0, "discountamount": 3235.0, "currencycode": "INR", "priority": 1000000, "isfreeshipmentavailable": false, "shipmentduration": 7, "_keywords": [ "Call", "Email", "doctor", "product", "fatigue", "WhatsApp", "treatment", "schedules", "ENZULAMIDE", "monitoring", "hot flashes", "information", "sterisonline", "hypertension", "sterispharma", "prostate cancer", "Enzalutamide 40mg", "prescribed dosages", "androgen receptors", "cancer cell growth", "Common side effects", "comprehensive guidance" ], "isarchived": false, "isavailable": true, "applicationid": null, "productindex": 1527, "imageuri": "https://productimages.withfloats.com/actual/667d2a356c582d228f45a098.png", "tileimageuri": "https://productimages.withfloats.com/tile/667d2a356c582d228f45a098.png", "images": null, "totalqueries": 0, "gpid": null, "groupproductid": null, "createdon": "2024-06-07T10:40:56.587Z", "updatedon": "2026-03-16T08:18:18.117Z", "buyonlinelink": null, "producturl": "http://WWW.STERISINDIA.COM//enzalutamide-40mg/1527", "availableunits": -1.0, "iscodavailable": false, "isprepaidonlineavailable": false, "maxcodorders": 0, "maxprepaidonlineorders": 0, "uniquepaymenturl": null, "brandname": "ENZULAMIDE 40", "category": "Oncology", "tags": [ "enzalutamide 40 mg side effects", "enzalutamide 40 mg brands in india", "enzalutamide 40 mg uses in hindi", "enzalutamide 40 mg dosage", "advanced prostate cancer", "prostate cancer", "metastatic castration-resistant prostate cancer", "enzalutamide 40mg tablets", "enzalutamide 40 mg capsule", "enzalutamide 40mg uses", "enzalutamide 40mg dosage", "enzalutamide 40mg price in india", "enzalutamide 40mg composition", "enzalutamide 40mg working mechanism", "enzalutamide 40mg side effects", "enzalutamide 40mg benefits", "enzalutamide 40mg drug information", "enzalutamide 40mg therapy details", "enzalutamide 40mg oral capsule", "enzalutamide 40mg treatment option", "enzalutamide 40mg pharmaceutical uses", "enzalutamide 40mg branded tablets", "enzalutamide 40mg generic medicine", "enzalutamide 40mg manufacturer in india", "what is enzalutamide 40mg used for", "how enzalutamide 40mg works", "is enzalutamide 40mg safe", "enzalutamide 40mg tablet information", "enzalutamide 40mg dosage guidelines" ], "variants": false, "keyspecification": null, "otherspecifications": null, "pickupaddressreferenceid": "", "paymenttype": "UniquePaymentUrl", "producttype": "products", "hsncode": null, "gstslab": 0.001, "isnotforsale": false }, { "_id": "665da4a38e599e12c0ea679f", "fptag": "STERISHEALTHCARE", "merchantname": null, "customwidgets": null, "externalsourceid": null, "name": "IVADINE 7.5 14'S", "description": "IVADINE 7.5 14'S\nIvabradine (7.5mg)\nIVADINE 7.5 is a medication containing Ivabradine in a 7.5mg dosage strength, used for the management of certain heart conditions.\n\nUses:\n\nTreatment of chronic heart failure with reduced ejection fraction in patients who are stable and have a regular heartbeat.\nReduction of the risk of hospitalization for worsening heart failure symptoms in certain patients.\nDosage:\nThe recommended dose of IVADINE 7.5 may vary depending on the individual's condition and response to treatment. 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