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Product details
NICOMALOM 2 NICOMALOM 2 features Nicoumalone, also known as Acenocoumarol, as its active ingredient in a 2mg tablet formulation. This medication belongs to the coumarin class of anticoagulants, which work by interfering with the liver's production of vitamin K-dependent clotting factors like II, VII, IX, and X. Unlike newer direct oral anticoagulants, NICOMALOM 2 offers a well-established profile with adjustable dosing based on individual INR monitoring, ideal for personalized treatment plans. Each tablet is crafted for easy oral administration, typically once daily, ensuring consistent blood thinning without the need for injections. The formulation ensures rapid absorption, with peak effects within hours, allowing for effective clot prevention in high-risk scenarios. Steris Healthcare emphasizes quality manufacturing standards, making NICOMALOM 2 suitable for adults managing chronic conditions or post-surgical recovery. Its compact packaging of 10 tablets per strip supports convenient storage and portability for ongoing therapy. Key Uses NICOMALOM 2 excels in preventing and treating thromboembolic disorders where blood clots pose immediate dangers. Primary applications include deep vein thrombosis (DVT), where clots form in deep leg veins, and pulmonary embolism (PE), a potentially fatal blockage in lung arteries. Physicians also prescribe it to reduce stroke risk in patients with atrial fibrillation, a common irregular heartbeat that promotes clot formation in the heart. Beyond these, NICOMALOM 2 prevents clots after surgeries like hip or knee replacements, or in those with mechanical heart valves. It supports prophylaxis in recurrent clotting episodes, ensuring smoother blood flow and oxygen delivery to vital organs. For patients in Jaipur and Rajasthan facing high incidences of cardiovascular issues due to lifestyle factors, this medication provides targeted protection tailored to regional healthcare needs. Mechanism of Action NICOMALOM 2 disrupts the clotting cascade by blocking vitamin K epoxide reductase, an enzyme essential for regenerating vitamin K. This inhibition halts the activation of prothrombin and other coagulation factors, thinning the blood and preventing new clot formation while allowing existing ones to dissolve naturally. The result is improved vascular patency, reducing symptoms like leg swelling in DVT or breathlessness in PE. Therapeutic levels are maintained through regular INR testing, typically targeting 2.0-3.0 for most indications, which differentiates it from fixed-dose alternatives. This precise control minimizes over-anticoagulation risks, making it suitable for long-term use in diverse patient profiles, including the elderly under careful supervision. Key Benefits Patients using NICOMALOM 2 experience significant reductions in clot-related hospitalizations, with studies showing up to 80% lower stroke incidence in atrial fibrillation cases. Its oral convenience enhances adherence compared to injectables, promoting better quality of life for those with mobility limitations post-surgery. Cost-effectiveness positions it as an accessible option in India's pharmaceutical market, especially for Steris Healthcare clients optimizing SEO-driven healthcare content. Additional advantages include reversibility with vitamin K administration in emergencies and compatibility with dietary adjustments for stable INR. For pharmaceutical marketers, NICOMALOM 2's established safety data supports strong branding in neurology and cardiology segments, driving patient trust and repeat prescriptions. Benefit Description Clinical Impact Stroke Prevention Lowers risk in atrial fibrillation by 60-70% Fewer neurological emergencies Post-Surgical Protection Reduces thromboembolism after orthopedic procedures Shorter recovery times DVT/PE Management Halts clot progression effectively Improved mobility and oxygenation Long-Term Safety Adjustable dosing via INR monitoring Sustained therapy without frequent switches Affordability Competitive pricing in Indian market High accessibility for diverse demographics Potential Side Effects While effective, NICOMALOM 2 carries bleeding risks as its primary concern, including easy bruising, gum bleeding, or prolonged cuts. Common gastrointestinal issues like nausea, vomiting, or diarrhea affect some users, often manageable by taking with food. Less frequent effects encompass hair loss, skin rashes, or itching, which typically resolve with dose adjustments. Rare but serious reactions involve heavy menstrual bleeding, nosebleeds, or internal hemorrhage signaled by black stools or blood in urine—prompt medical attention is crucial. Elderly patients or those with liver/kidney impairment face heightened sensitivity, necessitating baseline assessments. Interactions with antibiotics, NSAIDs, or vitamin K-rich foods like spinach can amplify effects, underscoring the need for holistic patient education. Side Effect Category Examples Management Tips Common (Mild) Bruising, nausea, diarrhea Take with meals; monitor diet Serious (Bleeding) Nosebleeds, heavy periods, wounds Seek immediate care; INR checks Rare Hair loss, rash, appetite loss Dose tweak; symptomatic relief Drug/Food Interactions Warfarin-like potentiators, greens Inform doctor of all intake Dosage and Safety Precautions Standard initial dosing starts at 2-4 mg daily, titrated per INR response, often 1-10mg maintenance. Children and the elderly require caution with lower starts. Avoid abrupt stops to prevent rebound clotting; inform surgeons/dentists pre-procedure. Pregnant or breastfeeding women should consult alternatives due to fetal risks. Regular prothrombin time tests ensure efficacy, with lifestyle advice like avoiding contact sports minimizing injury. Store at room temperature, away from moisture. Conclusion NICOMALOM 2 delivers robust anticoagulation for clot prevention, balancing potent benefits against manageable risks through vigilant monitoring. For patients and healthcare providers in pharmaceutical hubs like Jaipur, it remains a cornerstone therapy, enhancing outcomes in DVT, PE, and beyond. Always prioritize professional guidance for optimal results.
