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Eltrombopag Olamine Tablets 50 mg, marketed under the brand name LTROLAMINE 50, is a prescription medicine widely used in the management of low platelet count (thrombocytopenia) associated with certain blood disorders. It belongs to a class of medicines known as thrombopoietin receptor agonists, which work by stimulating platelet production in the bone marrow. LTROLAMINE 50 has become an important therapeutic option for patients who struggle with chronic platelet deficiency and are at increased risk of bleeding. With proven efficacy and a well-defined mechanism of action, this medication plays a crucial role in improving patient outcomes and quality of life. What is Eltrombopag Olamine Tablets 50 mg? Eltrombopag Olamine Tablets 50 mg is an oral medication designed to increase platelet counts in patients whose body does not produce enough platelets naturally. Platelets are essential blood components responsible for clot formation and prevention of excessive bleeding. LTROLAMINE 50 is commonly prescribed for: Chronic Immune Thrombocytopenia (ITP) Severe Aplastic Anemia Thrombocytopenia associated with chronic Hepatitis C infection (in specific cases) By improving platelet levels, LTROLAMINE 50 helps reduce bleeding risks and supports safer daily functioning for patients. Uses of LTROLAMINE 50 LTROLAMINE 50 is primarily used in the treatment of conditions characterized by low platelet counts, including: 1. Chronic Immune Thrombocytopenia (ITP) In patients with ITP, the immune system mistakenly destroys platelets. LTROLAMINE 50 stimulates platelet production, helping maintain a safer platelet count and lowering the risk of spontaneous bleeding. 2. Severe Aplastic Anemia In aplastic anemia, the bone marrow fails to produce sufficient blood cells. Eltrombopag Olamine supports bone marrow activity, leading to improved platelet and blood cell production when other treatments are ineffective. 3. Hepatitis C–Associated Thrombocytopenia Some patients with chronic Hepatitis C experience low platelet counts that limit antiviral therapy. LTROLAMINE 50 may be used to raise platelet levels, enabling continuation of essential treatment under medical supervision. How LTROLAMINE 50 Works Eltrombopag Olamine acts as a thrombopoietin receptor agonist. It binds to and activates the thrombopoietin (TPO) receptor found on bone marrow cells. This activation triggers a signaling process that stimulates the production of megakaryocytes—the cells responsible for forming platelets. Unlike platelet transfusions, which provide a temporary solution, LTROLAMINE 50 encourages the body to produce its own platelets, offering a more sustainable approach to managing thrombocytopenia. Key Benefits of LTROLAMINE 50 LTROLAMINE 50 offers several clinically significant benefits: 1. Increases Platelet Count Naturally By stimulating bone marrow activity, LTROLAMINE 50 helps raise platelet levels without relying on transfusions. 2. Reduces Bleeding Risk Maintaining adequate platelet counts significantly lowers the risk of bruising, nosebleeds, gum bleeding, and internal bleeding. 3. Oral and Convenient Therapy As an oral tablet, LTROLAMINE 50 is easy to administer and more comfortable for long-term use compared to injectable alternatives. 4. Improves Quality of Life By stabilizing platelet levels, patients can lead more active, confident lives with fewer hospital visits. 5. Useful in Refractory Cases LTROLAMINE 50 is effective even in patients who do not respond adequately to first-line therapies like corticosteroids or immunoglobulins. Dosage and Administration The dosage of LTROLAMINE 50 is determined by the treating physician based on: Platelet count Underlying condition Liver function Patient response to therapy The tablet is usually taken once daily, preferably on an empty stomach. Certain foods and supplements, especially those containing calcium, iron, magnesium, or aluminum, may interfere with absorption and should be avoided close to dosing time. Patients must strictly follow medical advice and undergo regular blood tests to monitor platelet levels and liver function. Possible Side Effects of LTROLAMINE 50 Like all medicines, LTROLAMINE 50 may cause side effects, although not everyone experiences them. Common Side Effects Headache Nausea or vomiting Fatigue Diarrhea Muscle or joint pain These effects are generally mild and tend to improve as the body adjusts to the medication. Less Common but Serious Side Effects Elevated liver enzymes Risk of blood clots if platelet counts become too high Liver function abnormalities Cataract development with long-term use (rare) Patients should immediately inform their healthcare provider if they notice symptoms such as yellowing of the skin or eyes, severe abdominal pain, chest pain, or sudden swelling in limbs. Precautions and Warnings LTROLAMINE 50 should only be used under strict medical supervision. Regular blood tests are essential to avoid excessive platelet increase. Caution is advised in patients with liver disease. Pregnant or breastfeeding women should consult their doctor before use. The medicine should not be stopped abruptly without medical advice. Conclusion Eltrombopag Olamine Tablets 50 mg (LTROLAMINE 50) is a clinically proven and effective therapy for managing thrombocytopenia associated with serious blood disorders. By stimulating the body’s natural platelet production, LTROLAMINE 50 helps reduce bleeding risk, minimize hospital dependence, and improve overall patient well-being.
