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BENZTETRA 25 contains the active ingredient tetrabenazine 25mg, a specialized medication used primarily to manage involuntary movements associated with neurological disorders. Tetrabenazine is classified as a vesicular monoamine transporter 2 (VMAT2) inhibitor and works by regulating the levels of neurotransmitters such as dopamine, serotonin, norepinephrine, and histamine in the brain. This correction of chemical imbalances helps reduce excessive and uncontrolled muscle movements. BENZTETRA 25 is especially valuable for patients suffering from movement disorders that significantly impact their daily functioning. It helps improve motor control, thereby enhancing quality of life for those affected. This medication is prescribed mainly to treat chorea—a movement disorder characterized by jerky, irregular, and uncontrollable muscle movements—that is caused by Huntington disease. What is BENZTETRA 25? BENZTETRA 25 is a therapeutic tablet containing tetrabenazine 25mg, designed to treat involuntary movements (chorea) linked to Huntington disease. It does not cure Huntington disease nor address cognitive or psychiatric symptoms of the disease but effectively reduces the severity of abnormal movements by altering neurotransmitter activity in the brain. Uses of BENZTETRA 25 To treat chorea (a movement disorder) that is caused by Huntington disease. To control involuntary muscle movements in Huntington’s disease patients. Management of other hyperkinetic movement disorders as determined by a healthcare provider (such as tardive dyskinesia or Tourette syndrome in some cases). To reduce excessive motor activity caused by abnormal nerve signaling in the brain, improving voluntary muscle control. Side Effects of BENZTETRA 25 Drowsiness and fatigue, which may affect alertness. Insomnia or difficulty sleeping. Nausea, vomiting, or abdominal discomfort. Parkinsonism symptoms such as tremors, muscle rigidity, and slowed movements (bradykinesia). Mood alterations including depression, anxiety, and in severe cases, suicidal thoughts. Rare serious reactions like allergic responses, heart rhythm irregularities, or neuroleptic malignant syndrome (characterized by high fever, muscle stiffness). Precautions Before Using BENZTETRA 25 Inform your doctor if you have a history of depression, suicidal thoughts, or any psychiatric illness. Avoid use if you have severe liver disease or have recently taken monoamine oxidase inhibitors (MAOIs). Caution in patients with cardiac issues due to potential QT interval prolongation. Use with care when driving or operating machinery as BENZTETRA 25 may cause dizziness or drowsiness. Do not stop the medication suddenly without consulting your healthcare provider, as symptoms might worsen. Regular monitoring by a healthcare professional is recommended to assess side effects and efficacy. Drug Interactions: What Drugs Interact with BENZTETRA 25? MAO inhibitors such as isocarboxazid, phenelzine, selegiline, and others can cause dangerous interactions and should not be used concurrently. Other drugs that affect serotonin levels, including selective serotonin reuptake inhibitors (SSRIs), may increase the risk of serotonin syndrome. Caution with other medications known to prolong the QT interval or those affecting dopamine systems. Interactions with neuroleptics or antipsychotics require close medical supervision due to additive effects on movement and mood. Conclusion BENZTETRA 25, containing tetrabenazine 25mg, is a vital medication for managing chorea associated with Huntington disease by modulating neurotransmitter levels in the brain to reduce involuntary movements. While it offers substantial benefits in improving motor control, careful attention to side effects, precautions, and drug interactions is essential for safe and effective use. Always follow the guidance of a healthcare professional when using BENZTETRA 25 to ensure optimal outcomes and safety.