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DIOWELPREX 250 ORAL SOLUTION Divalproex (250mg/5ml) Introduction DIOWELPREX 250 ORAL SOLUTION contains Divalproex (250mg/5ml), an anticonvulsant and mood-stabilizing medication used to treat various neurological and psychiatric conditions. It is particularly effective in managing epilepsy, bipolar disorder, and preventing migraine headaches. Composition Divalproex Sodium (250mg/5ml): A stable coordination compound comprised of sodium valproate and valproic acid in a 1:1 molar relationship, providing a source of valproate ion which exhibits anticonvulsant and mood-stabilizing properties. Mechanism of Action Divalproex works by increasing the levels of gamma-aminobutyric acid (GABA) in the brain, an inhibitory neurotransmitter that helps calm neuronal activity. It stabilizes electrical activity in the brain, reducing the frequency and severity of seizures, stabilizing mood in bipolar disorder, and preventing migraine headaches by altering the way nerves send signals. Indications DIOWELPREX 250 ORAL SOLUTION is indicated for: Epilepsy: Used to control various types of seizures including complex partial seizures and simple and complex absence seizures. Bipolar Disorder: Helps in the management of manic episodes associated with bipolar disorder. Migraine Prophylaxis: Used to prevent migraine headaches. Dosage and Administration Epilepsy: The initial dose is typically 10-15 mg/kg/day, gradually increased as needed and tolerated to achieve optimal clinical response. Bipolar Disorder: The initial dose is generally 750 mg/day, given in divided doses, adjusted according to clinical response. Migraine Prophylaxis: The initial dose is usually 250 mg twice daily, adjusted as necessary. It is essential to follow the prescribed dosage and administration instructions provided by a healthcare professional. The oral solution should be measured accurately using a dosing syringe or cup to ensure the correct dose is administered. Side Effects Common side effects may include: Nausea Drowsiness Dizziness Tremor Hair loss Weight gain Gastrointestinal disturbances More severe side effects can include: Liver damage Pancreatitis Thrombocytopenia (low platelet count) Hyperammonemia (high levels of ammonia in the blood) Precautions Liver Function: Regular monitoring of liver function tests is recommended due to the risk of hepatotoxicity. Pancreatitis: Patients should be monitored for signs of pancreatitis. Pregnancy: Divalproex is associated with an increased risk of congenital malformations and should be used during pregnancy only if absolutely necessary and prescribed by a healthcare provider. Bleeding Disorders: Caution is advised in patients with known bleeding disorders due to the risk of thrombocytopenia. Drug Interactions Antiepileptic Drugs: Concurrent use with other antiepileptic drugs may require dosage adjustments. Warfarin: May enhance the anticoagulant effect, necessitating close monitoring of INR levels. Topiramate: Co-administration can lead to hyperammonemia and encephalopathy. Alcohol: Should be avoided as it can exacerbate the side effects of Divalproex and further impair mental and motor skills. Conclusion DIOWELPREX 250 ORAL SOLUTION is an effective medication for managing epilepsy, bipolar disorder, and preventing migraines. With its active ingredient Divalproex, it helps stabilize neuronal activity and mood. Proper dosage and administration under the guidance of a healthcare professional are essential to maximize benefits and minimize potential side effects. Regular monitoring and adherence to medical advice ensure the safe and effective use of DIOWELPREX 250 ORAL SOLUTION. For further information: EMAIL: info@sterispharma.com / contact@sterispharma.com CALL/WHATSAPP: 7877551268, 7849827488 Order NOW