AMBRISTAR 5 Ambrisentan (5mg) Ambrisentan is a medication used in the treatment of pulmonary arterial hypertension (PAH). It is an endothelin receptor antagonist, specifically targeting endothelin A receptors. By blocking these receptors, ambrisentan helps to relax and dilate blood vessels in the lungs, reducing the blood pressure in the pulmonary arteries and improving blood flow. Here are some key points about Ambrisentan: Indication: AMBRISTAR 5 is primarily prescribed for the treatment of pulmonary arterial hypertension (PAH) to improve exercise ability and delay clinical worsening. Mechanism of Action: It works by blocking the effects of endothelin, a substance that constricts blood vessels and increases blood pressure. By inhibiting endothelin receptors, ambrisentan helps to relax blood vessels, reducing the resistance in the pulmonary circulation. Dosage: The typical starting dose for ambrisentan is 5 mg once daily. However, the dosage may be adjusted based on the individual patient's response and tolerability. It is important for patients to follow the prescribed dosage and regimen. Monitoring: Regular monitoring of liver function is essential during treatment with ambrisentan, as the drug has been associated with liver enzyme elevations. Patients may also undergo periodic blood tests to check for potential adverse effects. Contraindications and Precautions: AMBRISTAR 5 is contraindicated in patients with idiosyncratic reactions to ambrisentan, patients with moderate or severe hepatic impairment, and during pregnancy due to the risk of fetal harm. It is important to inform healthcare providers about all existing medical conditions and medications before starting ambrisentan. Side Effects: Common side effects include swelling of the ankles and legs (peripheral edema), nasal congestion, flushing, and headache. Serious side effects can include liver problems, anemia, and fluid retention. Pregnancy Category: Ambrisentan is contraindicated during pregnancy due to the potential for serious harm to the fetus. Female patients of childbearing potential are typically required to use reliable contraception during treatment and undergo regular pregnancy tests. As with any medication, it is crucial for patients to follow their healthcare provider's instructions, report any side effects promptly, and attend regular follow-up appointments for monitoring. This information is a general overview, and specific details may vary based on individual circumstances and prescribing practices. Steris Healthcare Pvt. Ltd. is a Leading Pharmaceutical Company in India. Established in the year of May 2018. We have 750+ Products & 16+ Super Specialty Segments. Every week we have a new product in our portfolio. In Last 4 years we are dealing in Chronic Therapy and in 4 years we grow by 200% Annually, because we deal in high quality medicine. Steris medicine manufactures at WHO-GMP Approved Plants & We have Legal manufacturing contracts with all leading manufacturers of India. Today we have 1000+ Business Franchise Partners in PAN India. Steris's medicine supply in India's Top or Reputed Hospitals, Pharmacy, Government use or Railway use. Grow with a similar pace with the STERIS. Be first to launch like us. For further information please contact: info@sterispharma.com order now: https://www.sterisonline.com/product/ambristar-5-134059